ARF6 and RAB11FIP4

Number of citations of the paper that reports this interaction (PMID 16148947)
77

Data Source:
BioGRID (affinity chromatography technology, imaging technique, pull down)

		ARF6	RAB11FIP4
Gene Name		ADP-ribosylation factor 6	RAB11 family interacting protein 4 (class II)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Ruffle Endosome Early Endosome Golgi Apparatus Plasma Membrane Focal Adhesion Cell Cortex Membrane Endocytic Vesicle Midbody Filopodium Membrane Cleavage Furrow Recycling Endosome Membrane Extracellular Vesicular Exosome	Extracellular Space Endosome Endocytic Vesicle Midbody Cleavage Furrow Recycling Endosome Membrane
	Molecular Function	GTPase Activity Protein Binding GTP Binding Thioesterase Binding	Calcium Ion Binding Protein Binding Rab GTPase Binding ADP-ribosylation Factor Binding Protein Homodimerization Activity
	Biological Process	Liver Development Movement Of Cell Or Subcellular Component Cell Cycle Cell Adhesion Small GTPase Mediated Signal Transduction Metabolic Process Protein Transport Vesicle-mediated Transport Positive Regulation Of Actin Filament Polymerization Cortical Actin Cytoskeleton Organization Ruffle Organization Myeloid Cell Apoptotic Process Protein Localization To Cell Surface Regulation Of Rac Protein Signal Transduction Protein Localization To Endosome Negative Regulation Of Receptor-mediated Endocytosis Cell Division Regulation Of Filopodium Assembly Regulation Of Dendritic Spine Development Positive Regulation Of Establishment Of Protein Localization To Plasma Membrane Establishment Of Epithelial Cell Polarity Hepatocyte Apoptotic Process	Cytokinesis Transport Viral Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		28 interactors: AP1B1 AP3B1 AP3D1 AP3S2 APP ARFIP2 ARRB1 ARRB2 ASAP2 ASAP3 ATP6V0C CAPN1 CHRM3 CYTH1 CYTH2 EXOC5 EZR GGA1 IKBKG ITSN1 MPP5 PIP5K1A PIP5K1C PLD1 RAB11FIP3 RAB11FIP4 RAB11FIP5 ZNF709	7 interactors: ARF6 GFI1B KIAA0368 RAB11A RAB11FIP2 RAB11FIP3 RAB11FIP5
Entrez ID		382	84440
HPRD ID		02714	11466
Ensembl ID			ENSG00000131242
Uniprot IDs		P62330	Q86YS3
PDB IDs		1E0S 2A5D 2A5F 2A5G 2BAO 2BAU 2J5X 2W83 3LVQ 3LVR 3N5C 3PCR 4FME 4KAX
Enriched GO Terms of Interacting Partners?		Vesicle-mediated Transport Cellular Localization Protein Localization Establishment Of Localization In Cell Establishment Of Protein Localization Transport Establishment Of Vesicle Localization Vesicle Localization Synaptic Vesicle Transport Protein Transport Movement Of Cell Or Subcellular Component Axon Cargo Transport Endocytosis Establishment Of Organelle Localization Receptor Metabolic Process Regulation Of GTPase Activity Anterograde Synaptic Vesicle Transport Regulation Of ARF Protein Signal Transduction Intracellular Transport Chemotaxis Anterograde Axon Cargo Transport Regulation Of Ras Protein Signal Transduction Organelle Localization Cellular Protein Localization Positive Regulation Of GTPase Activity Positive Regulation Of Hydrolase Activity Regulation Of Small GTPase Mediated Signal Transduction Microtubule-based Transport Receptor Internalization Cytoskeleton-dependent Intracellular Transport Response To External Stimulus Antigen Processing And Presentation, Exogenous Lipid Antigen Via MHC Class Ib Positive Regulation Of NK T Cell Differentiation Positive Regulation Of Catalytic Activity Regulation Of Body Fluid Levels Synaptic Transmission Actin Cytoskeleton Organization Locomotion Cell-cell Signaling Platelet Activation Cytoskeletal Anchoring At Plasma Membrane Regulation Of Signaling Actin Filament-based Process Regulation Of Intracellular Signal Transduction G-protein Coupled Receptor Internalization Blood Coagulation Hemostasis Regulation Of Signal Transduction Post-Golgi Vesicle-mediated Transport Desensitization Of G-protein Coupled Receptor Protein Signaling Pathway	Insulin Secretion Involved In Cellular Response To Glucose Stimulus Vesicle-mediated Transport Renal Water Homeostasis Insulin Secretion Water Transport Fluid Transport Multicellular Organismal Water Homeostasis Exocytosis Regulated Secretory Pathway Cellular Response To Glucose Stimulus Water Homeostasis Peptide Hormone Secretion Peptide Secretion Cell Division Cellular Localization Cellular Glucose Homeostasis Cellular Response To Carbohydrate Stimulus Hormone Secretion Multivesicular Body Assembly Regulation Of Multivesicular Body Size Secretion By Cell Hormone Transport Peptide Transport Renal System Process Protein Transport Cytokinesis Establishment Of Protein Localization Establishment Of Cell Polarity Protein Secretion Multivesicular Body Organization Secretion Amide Transport Response To Glucose Regulation Of Endosome Size Exosomal Secretion Regulation Of Protein Localization Protein Localization Establishment Or Maintenance Of Cell Polarity Response To Carbohydrate Establishment Of Localization In Cell Chemical Homeostasis Glucose Homeostasis Endosomal Transport Myeloid Cell Apoptotic Process Cellular Response To Acidic PH Plasma Membrane To Endosome Transport Astral Microtubule Organization Regulation Of Hormone Levels Protein Localization To Endosome Regulation Of Cellular Component Size
Tagcloud ?		accessible cellubrevin cho colocalized compartment cryoimmunogold endocytic endosomal gdp gtpase horseradish hrp invaginations localize localizes morphologically pericentriolar perinuclear perturbs q67l recycling resembled ribosylation shortly t27n tracer uniquely vesicles
Tagcloud (Difference) ?		accessible cellubrevin cho colocalized compartment cryoimmunogold endocytic endosomal gdp gtpase horseradish hrp invaginations localize localizes morphologically pericentriolar perinuclear perturbs q67l recycling resembled ribosylation shortly t27n tracer uniquely vesicles
Tagcloud (Intersection) ?