AP3D1 and VPS41

Number of citations of the paper that reports this interaction (PMID 10559961)
36

Data Source:
HPRD (in vivo, in vitro)

		AP3D1	VPS41
Gene Name		adaptor-related protein complex 3, delta 1 subunit	vacuolar protein sorting 41 homolog (S. cerevisiae)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Membrane Nucleoplasm Lysosomal Membrane Golgi Apparatus Endosome Membrane Membrane Membrane Coat Terminal Bouton	Lysosomal Membrane Early Endosome Late Endosome Golgi-associated Vesicle Cytosol Microtubule Cytoskeleton Membrane HOPS Complex CORVET Complex
	Molecular Function	Transporter Activity	Molecular_function Protein Binding Microtubule Binding Zinc Ion Binding GTPase Binding
	Biological Process	Eye Pigment Biosynthetic Process Intracellular Protein Transport Anterograde Axon Cargo Transport Melanosome Organization Protein Localization To Organelle Endosome To Melanosome Transport Antigen Processing And Presentation, Exogenous Lipid Antigen Via MHC Class Ib Anterograde Synaptic Vesicle Transport Synaptic Vesicle Membrane Organization Positive Regulation Of NK T Cell Differentiation Regulation Of Sequestering Of Zinc Ion Protein Localization To Membrane	Protein Targeting To Vacuole Biological_process Vesicle-mediated Transport Regulation Of SNARE Complex Assembly Vacuole Fusion, Non-autophagic Golgi Vesicle Transport
Pathways
Drugs
Diseases
GWAS			Cognitive performance ( 19734545)
Protein-Protein Interactions		9 interactors: AP3S1 AP3S2 ARF1 ARF6 CTGF RUFY1 SLC30A3 VAMP7 VPS41	9 interactors: AKTIP AP3D1 APP HOOK1 HOOK2 HOOK3 MON1B UBE2U ZNF512B
Entrez ID		8943	27072
HPRD ID		06260	10402
Ensembl ID		ENSG00000065000	ENSG00000006715
Uniprot IDs		O14617	E9PF36 P49754
PDB IDs		4AFI
Enriched GO Terms of Interacting Partners?		Protein Transport Vesicle-mediated Transport Establishment Of Protein Localization Regulation Of Vesicle-mediated Transport Protein Localization Transport Cellular Localization Regulation Of Cellular Component Organization Establishment Of Localization In Cell Anterograde Synaptic Vesicle Transport Regulation Of Endocytosis Anterograde Axon Cargo Transport Establishment Of Vesicle Localization Vesicle Localization Cellular Protein Localization Intracellular Transport Golgi Vesicle Transport Axon Cargo Transport Establishment Of Organelle Localization Intracellular Protein Transport Regulation Of Organelle Organization Regulation Of Actin Cytoskeleton Organization Organelle Fusion Regulation Of Actin Filament-based Process Regulation Of Protein Targeting To Vacuolar Membrane Vacuole Fusion, Non-autophagic Vacuolar Transport Organelle Localization Post-Golgi Vesicle-mediated Transport Regulation Of Cytoskeleton Organization Synaptic Vesicle Transport Organ Senescence Membrane Fusion Microtubule-based Transport Positive Regulation Of Histamine Secretion By Mast Cell Regulation Of Histamine Secretion By Mast Cell Triglyceride Transport Extracellular Matrix Constituent Secretion Eosinophil Degranulation Cytoskeleton-dependent Intracellular Transport Response To Anoxia Positive Regulation Of G0 To G1 Transition Movement Of Cell Or Subcellular Component Regulation Of Sequestering Of Zinc Ion Neutrophil Degranulation Positive Regulation Of Cardiac Muscle Contraction Positive Regulation Of Cytoskeleton Organization Vesicle Organization Myeloid Cell Apoptotic Process Regulation Of SNARE Complex Assembly	Early Endosome To Late Endosome Transport Endosome To Lysosome Transport Endosome Organization Lysosomal Transport Lysosome Organization Endosomal Transport Vacuolar Transport Vacuole Organization Vesicle-mediated Transport Endomembrane System Organization Cytoplasmic Transport Intracellular Transport Establishment Of Localization In Cell Cellular Localization Protein Transport Establishment Of Protein Localization Axon Cargo Transport Organelle Organization Protein Localization Transport Synaptic Growth At Neuromuscular Junction Synaptic Vesicle Membrane Organization Microtubule-based Transport Collateral Sprouting In Absence Of Injury Cytoskeleton-dependent Intracellular Transport Regulation Of Protein Binding Eye Pigment Biosynthetic Process Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Regulation Of Sequestering Of Zinc Ion Microtubule-based Process Axon Choice Point Recognition Eye Pigmentation Antigen Processing And Presentation, Exogenous Lipid Antigen Via MHC Class Ib Positive Regulation Of NK T Cell Differentiation Pigment Granule Maturation Endosome To Melanosome Transport Neuron Remodeling Cellular Pigment Accumulation Regulation Of Binding Microtubule Anchoring At Centrosome Microtubule Anchoring At Microtubule Organizing Center Negative Regulation Of Neurogenesis Protein Localization To Centrosome Golgi Localization Microtubule-based Movement Negative Regulation Of Cell Development Cellular Copper Ion Homeostasis Interkinetic Nuclear Migration
Tagcloud ?		18s actb bestkeeper c2c12 cdc40 csnk2a2 dystrophic dystrophin exceptionally fbxo38 fbxw2 gapdh genorm h2k2b4 h2ksf1 htatsf1 informative mef2c myoblasts myod myogenesis myogenic myogenin normalization normalizing normfinder packages pak1ip1 zfp91
Tagcloud (Difference) ?		18s actb bestkeeper c2c12 cdc40 csnk2a2 dystrophic dystrophin exceptionally fbxo38 fbxw2 gapdh genorm h2k2b4 h2ksf1 htatsf1 informative mef2c myoblasts myod myogenesis myogenic myogenin normalization normalizing normfinder packages pak1ip1 zfp91
Tagcloud (Intersection) ?