ARF6 and AP3S2

Number of citations of the paper that reports this interaction (PMID 11926829)
12

Data Source:
BioGRID (pull down)

		ARF6	AP3S2
Gene Name		ADP-ribosylation factor 6	adaptor-related protein complex 3, sigma 2 subunit
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Ruffle Endosome Early Endosome Golgi Apparatus Plasma Membrane Focal Adhesion Cell Cortex Membrane Endocytic Vesicle Midbody Filopodium Membrane Cleavage Furrow Recycling Endosome Membrane Extracellular Vesicular Exosome	Golgi Apparatus AP-3 Adaptor Complex Cytoplasmic Vesicle Membrane
	Molecular Function	GTPase Activity Protein Binding GTP Binding Thioesterase Binding	Protein Transporter Activity
	Biological Process	Liver Development Movement Of Cell Or Subcellular Component Cell Cycle Cell Adhesion Small GTPase Mediated Signal Transduction Metabolic Process Protein Transport Vesicle-mediated Transport Positive Regulation Of Actin Filament Polymerization Cortical Actin Cytoskeleton Organization Ruffle Organization Myeloid Cell Apoptotic Process Protein Localization To Cell Surface Regulation Of Rac Protein Signal Transduction Protein Localization To Endosome Negative Regulation Of Receptor-mediated Endocytosis Cell Division Regulation Of Filopodium Assembly Regulation Of Dendritic Spine Development Positive Regulation Of Establishment Of Protein Localization To Plasma Membrane Establishment Of Epithelial Cell Polarity Hepatocyte Apoptotic Process	Intracellular Protein Transport Anterograde Axon Cargo Transport Anterograde Synaptic Vesicle Transport
Pathways
Drugs
Diseases
GWAS			Type 2 diabetes ( 21874001)
Protein-Protein Interactions		28 interactors: AP1B1 AP3B1 AP3D1 AP3S2 APP ARFIP2 ARRB1 ARRB2 ASAP2 ASAP3 ATP6V0C CAPN1 CHRM3 CYTH1 CYTH2 EXOC5 EZR GGA1 IKBKG ITSN1 MPP5 PIP5K1A PIP5K1C PLD1 RAB11FIP3 RAB11FIP4 RAB11FIP5 ZNF709	6 interactors: AP3B1 AP3D1 AP3S1 ARF1 ARF6 E2F4
Entrez ID		382	10239
HPRD ID		02714	03880
Ensembl ID			ENSG00000157823
Uniprot IDs		P62330	P59780
PDB IDs		1E0S 2A5D 2A5F 2A5G 2BAO 2BAU 2J5X 2W83 3LVQ 3LVR 3N5C 3PCR 4FME 4KAX
Enriched GO Terms of Interacting Partners?		Vesicle-mediated Transport Cellular Localization Protein Localization Establishment Of Localization In Cell Establishment Of Protein Localization Transport Establishment Of Vesicle Localization Vesicle Localization Synaptic Vesicle Transport Protein Transport Movement Of Cell Or Subcellular Component Axon Cargo Transport Endocytosis Establishment Of Organelle Localization Receptor Metabolic Process Regulation Of GTPase Activity Anterograde Synaptic Vesicle Transport Regulation Of ARF Protein Signal Transduction Intracellular Transport Chemotaxis Anterograde Axon Cargo Transport Regulation Of Ras Protein Signal Transduction Organelle Localization Cellular Protein Localization Positive Regulation Of GTPase Activity Positive Regulation Of Hydrolase Activity Regulation Of Small GTPase Mediated Signal Transduction Microtubule-based Transport Receptor Internalization Cytoskeleton-dependent Intracellular Transport Response To External Stimulus Antigen Processing And Presentation, Exogenous Lipid Antigen Via MHC Class Ib Positive Regulation Of NK T Cell Differentiation Positive Regulation Of Catalytic Activity Regulation Of Body Fluid Levels Synaptic Transmission Actin Cytoskeleton Organization Locomotion Cell-cell Signaling Platelet Activation Cytoskeletal Anchoring At Plasma Membrane Regulation Of Signaling Actin Filament-based Process Regulation Of Intracellular Signal Transduction G-protein Coupled Receptor Internalization Blood Coagulation Hemostasis Regulation Of Signal Transduction Post-Golgi Vesicle-mediated Transport Desensitization Of G-protein Coupled Receptor Protein Signaling Pathway	Anterograde Synaptic Vesicle Transport Anterograde Axon Cargo Transport Establishment Of Vesicle Localization Vesicle Localization Axon Cargo Transport Establishment Of Organelle Localization Antigen Processing And Presentation, Exogenous Lipid Antigen Via MHC Class Ib Positive Regulation Of NK T Cell Differentiation Organelle Localization Synaptic Vesicle Transport Microtubule-based Transport Cytoskeleton-dependent Intracellular Transport Protein Transport Vesicle-mediated Transport Establishment Of Protein Localization Melanosome Organization Pigment Granule Organization Vesicle Organization Microtubule-based Process Protein Localization Antigen Processing And Presentation Microtubule-based Movement Positive Regulation Of Alpha-beta T Cell Differentiation Cellular Localization Cellular Pigmentation Cellular Protein Localization Signaling Positive Regulation Of T Cell Differentiation Protein Localization To Organelle Cell Communication Movement Of Cell Or Subcellular Component Organelle Organization Intracellular Transport Positive Regulation Of Lymphocyte Differentiation Synaptic Transmission Pigmentation Regulation Of T Cell Differentiation Synaptic Vesicle Membrane Organization Regulation Of Lymphocyte Differentiation Establishment Of Localization In Cell Regulation Of Endocytosis Eye Pigment Biosynthetic Process Cell-cell Signaling Intracellular Protein Transport Positive Regulation Of T Cell Activation Positive Regulation Of Homotypic Cell-cell Adhesion Regulation Of Sequestering Of Zinc Ion Multi-ciliated Epithelial Cell Differentiation Positive Regulation Of Cell-cell Adhesion Eye Pigmentation
Tagcloud ?		accessible cellubrevin cho colocalized compartment cryoimmunogold endocytic endosomal gdp gtpase horseradish hrp invaginations localize localizes morphologically pericentriolar perinuclear perturbs q67l recycling resembled ribosylation shortly t27n tracer uniquely vesicles
Tagcloud (Difference) ?		accessible cellubrevin cho colocalized compartment cryoimmunogold endocytic endosomal gdp gtpase horseradish hrp invaginations localize localizes morphologically pericentriolar perinuclear perturbs q67l recycling resembled ribosylation shortly t27n tracer uniquely vesicles
Tagcloud (Intersection) ?