AP3D1 and SLC30A3

Number of citations of the paper that reports this interaction (PMID 14657250)
29

Data Source:
HPRD (in vitro)

		AP3D1	SLC30A3
Gene Name		adaptor-related protein complex 3, delta 1 subunit	solute carrier family 30 (zinc transporter), member 3
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Membrane Nucleoplasm Lysosomal Membrane Golgi Apparatus Endosome Membrane Membrane Membrane Coat Terminal Bouton	Cytoplasm Endosome Late Endosome Integral Component Of Plasma Membrane Synaptic Vesicle Membrane Cell Junction Synaptic Vesicle Membrane Neuron Projection
	Molecular Function	Transporter Activity	Zinc Transporting ATPase Activity
	Biological Process	Eye Pigment Biosynthetic Process Intracellular Protein Transport Anterograde Axon Cargo Transport Melanosome Organization Protein Localization To Organelle Endosome To Melanosome Transport Antigen Processing And Presentation, Exogenous Lipid Antigen Via MHC Class Ib Anterograde Synaptic Vesicle Transport Synaptic Vesicle Membrane Organization Positive Regulation Of NK T Cell Differentiation Regulation Of Sequestering Of Zinc Ion Protein Localization To Membrane	Transport Positive Regulation Of Transport Transmembrane Transport Regulation Of Sequestering Of Zinc Ion Zinc Ion Transmembrane Transport
Pathways			Metal ion SLC transporters Zinc efflux and compartmentalization by the SLC30 family Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds Zinc transporters SLC-mediated transmembrane transport
Drugs
Diseases
GWAS
Protein-Protein Interactions		9 interactors: AP3S1 AP3S2 ARF1 ARF6 CTGF RUFY1 SLC30A3 VAMP7 VPS41	4 interactors: AP3B1 AP3D1 AP3S1 NAALADL2
Entrez ID		8943	7781
HPRD ID		06260	11924
Ensembl ID		ENSG00000065000	ENSG00000115194
Uniprot IDs		O14617	F5H3B7 Q99726
PDB IDs		4AFI
Enriched GO Terms of Interacting Partners?		Protein Transport Vesicle-mediated Transport Establishment Of Protein Localization Regulation Of Vesicle-mediated Transport Protein Localization Transport Cellular Localization Regulation Of Cellular Component Organization Establishment Of Localization In Cell Anterograde Synaptic Vesicle Transport Regulation Of Endocytosis Anterograde Axon Cargo Transport Establishment Of Vesicle Localization Vesicle Localization Cellular Protein Localization Intracellular Transport Golgi Vesicle Transport Axon Cargo Transport Establishment Of Organelle Localization Intracellular Protein Transport Regulation Of Organelle Organization Regulation Of Actin Cytoskeleton Organization Organelle Fusion Regulation Of Actin Filament-based Process Regulation Of Protein Targeting To Vacuolar Membrane Vacuole Fusion, Non-autophagic Vacuolar Transport Organelle Localization Post-Golgi Vesicle-mediated Transport Regulation Of Cytoskeleton Organization Synaptic Vesicle Transport Organ Senescence Membrane Fusion Microtubule-based Transport Positive Regulation Of Histamine Secretion By Mast Cell Regulation Of Histamine Secretion By Mast Cell Triglyceride Transport Extracellular Matrix Constituent Secretion Eosinophil Degranulation Cytoskeleton-dependent Intracellular Transport Response To Anoxia Positive Regulation Of G0 To G1 Transition Movement Of Cell Or Subcellular Component Regulation Of Sequestering Of Zinc Ion Neutrophil Degranulation Positive Regulation Of Cardiac Muscle Contraction Positive Regulation Of Cytoskeleton Organization Vesicle Organization Myeloid Cell Apoptotic Process Regulation Of SNARE Complex Assembly	Anterograde Synaptic Vesicle Transport Anterograde Axon Cargo Transport Axon Cargo Transport Synaptic Vesicle Transport Positive Regulation Of NK T Cell Differentiation Antigen Processing And Presentation, Exogenous Lipid Antigen Via MHC Class Ib Microtubule-based Transport Cytoskeleton-dependent Intracellular Transport Establishment Of Vesicle Localization Vesicle Localization Melanosome Organization Microtubule-based Movement Pigment Granule Organization Establishment Of Organelle Localization Organelle Localization Positive Regulation Of Alpha-beta T Cell Differentiation Synaptic Transmission Cellular Pigmentation Microtubule-based Process Positive Regulation Of T Cell Differentiation Positive Regulation Of Lymphocyte Differentiation Cell-cell Signaling Intracellular Protein Transport Pigmentation Regulation Of T Cell Differentiation Regulation Of Lymphocyte Differentiation Cellular Protein Localization Protein Transport Vesicle Organization Positive Regulation Of T Cell Activation Vesicle-mediated Transport Synaptic Vesicle Membrane Organization Positive Regulation Of Homotypic Cell-cell Adhesion Establishment Of Protein Localization Movement Of Cell Or Subcellular Component Intracellular Transport Positive Regulation Of Cell-cell Adhesion Antigen Processing And Presentation Regulation Of T Cell Activation Eye Pigment Biosynthetic Process Positive Regulation Of Cell Activation Protein Localization Establishment Of Localization In Cell Regulation Of Sequestering Of Zinc Ion Regulation Of Cell-cell Adhesion Positive Regulation Of Cell Adhesion Eye Pigmentation Regulation Of Lymphocyte Activation Endosome To Melanosome Transport Pigment Granule Maturation
Tagcloud ?		18s actb bestkeeper c2c12 cdc40 csnk2a2 dystrophic dystrophin exceptionally fbxo38 fbxw2 gapdh genorm h2k2b4 h2ksf1 htatsf1 informative mef2c myoblasts myod myogenesis myogenic myogenin normalization normalizing normfinder packages pak1ip1 zfp91	absorption atomic carrier carriers cc concerning flame furnace graphite homozygotes kd micronutrient micronutrients modes mug polymorphisms rs11126936 rs561104 rs5854 rs5859 rs73924411 selenium selenoprotein sep15 solute spectrophotometry trace ultimately zinc
Tagcloud (Difference) ?		18s actb bestkeeper c2c12 cdc40 csnk2a2 dystrophic dystrophin exceptionally fbxo38 fbxw2 gapdh genorm h2k2b4 h2ksf1 htatsf1 informative mef2c myoblasts myod myogenesis myogenic myogenin normalization normalizing normfinder packages pak1ip1 zfp91	absorption atomic carrier carriers cc concerning flame furnace graphite homozygotes kd micronutrient micronutrients modes mug polymorphisms rs11126936 rs561104 rs5854 rs5859 rs73924411 selenium selenoprotein sep15 solute spectrophotometry trace ultimately zinc
Tagcloud (Intersection) ?