IGF1R and SHC1

  • Number of citations of the paper that reports this interaction (PMID 14764897)
  • 68
  • Data Source:
  • BioGRID (two hybrid, affinity chromatography technology, two hybrid, affinity chromatography technology, affinity chromatography technology)

IGF1R

SHC1

Gene Name insulin-like growth factor 1 receptor SHC (Src homology 2 domain containing) transforming protein 1
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 59 interactors: AMY2A APP ARHGEF12 CAV1 CBL CRK CRKL CSK DOK4 DOK5 EEA1 EHD1 ESR1 FFAR2 GIPC1 GNAI1 GNAI2 GNB2L1 GRB10 GRB14 IGF1 IGF2 IGFBP3 INS INSR IRS1 IRS2 IRS4 ITGB1 JAK1 JAK2 KCNIP3 KL KRT27 MAP3K5 MDM2 NEDD4 PIK3R1 PIK3R2 PIK3R3 PRKCD PRKD1 PTPN1 PTPN11 RASA1 RPL11 SH2B1 SHC1 SOCS1 SOCS2 SOCS3 SRC STAT3 UBC VAV3 YWHAB YWHAE YWHAG YWHAZ 134 interactors: ALK AP2A1 AP2A2 APP AXL BCL3 BCR C11orf58 CALCOCO2 CALD1 CBL CBLB CBLC CD22 CD247 CD3E CD81 CDH5 CEACAM1 CRK CRKL CSF1R CSF2RB CSF3R CSK DAG1 DDR1 DDR2 DOK1 DUSP23 EGFR EPHA2 EPOR EPS8 ERBB2 ERBB3 ERBB4 ESR1 FAM118B FCGR2A FCGR3A FGFR1 FLT1 FLT4 FYN GAB1 GAB2 GEMIN7 GH1 GHR GRAP GRAP2 GRB2 GRB7 HMOX2 IGF1R IL2 IL2RB IL2RG IL4R IL6ST ILK INPP5D INPPL1 INSR IRS1 IRS2 ITGB3 ITGB4 JAK2 KDR KRT18 LCK LCP2 LRP1 LTK LYN MAP4K1 MAPK1 MAPK14 MAPK6 MAPK8 MAPKAPK2 MET MME MPL MRPL44 MST1R NGFR NPM1 NTRK1 NTRK2 NTRK3 NUDT21 OSGEP PAG1 PAK1 PDGFRB PIK3C2B PIK3R1 PIK3R2 PLCG1 PLCG2 PLSCR1 PPAP2B PPP2R5A PRKCA PRKCD PRKRA PTK2 PTK2B PTPN11 PTPN12 PTPN2 PTPN6 RAPGEF1 RASA1 RET SH2B2 SHCBP1 SOS1 SOS2 SP1 SRC STAT5A STAT5B SUV39H2 SYK TEC TEK TPR VAV1 VAV3 ZAP70
Entrez ID 3480 6464
HPRD ID 00932 02780
Ensembl ID ENSG00000140443 ENSG00000160691
Uniprot IDs C9J5X1 P08069 P29353
PDB IDs 1IGR 1JQH 1K3A 1M7N 1P4O 2OJ9 2ZM3 3D94 3F5P 3I81 3LVP 3LW0 3NW5 3NW6 3NW7 3O23 3QQU 1MIL 1N3H 1OY2 1QG1 1SHC 1TCE 1WCP 2L1C
Enriched GO Terms of Interacting Partners?
Tagcloud ?
12q  12q21  14q31  15q25  16q23  18p  19q13  20p12  20pq  20q12  21q21  3p14  4pq  5p14  5q14  6p12  7p12  8q23  cardia  cdkn2  fist  gej  mlvi2  mts1  nrasl3  parentheses  ptpn1  rca1  xpq  xq25 
adaptors  assumptions  combinatorial  complexity  cooperativity  dealt  demodification  descriptions  disallow  hinders  hoc  lumped  modelling  obstacle  ode  odes  ordinary  pharmacology  phosphatases  plcgamma1  rasa1  reasonably  relaxed  retaining  shp2  simulate  subdomains  tyrosines  unphosphorylated 
Tagcloud (Difference) ?
12q  12q21  14q31  15q25  16q23  18p  19q13  20p12  20pq  20q12  21q21  3p14  4pq  5p14  5q14  6p12  7p12  8q23  cardia  cdkn2  fist  gej  mlvi2  mts1  nrasl3  parentheses  ptpn1  rca1  xpq  xq25 
adaptors  assumptions  combinatorial  complexity  cooperativity  dealt  demodification  descriptions  disallow  hinders  hoc  lumped  modelling  obstacle  ode  odes  ordinary  pharmacology  phosphatases  plcgamma1  rasa1  reasonably  relaxed  retaining  shp2  simulate  subdomains  tyrosines  unphosphorylated 
Tagcloud (Intersection) ?