IGF1R and PIK3R3

  • Number of citations of the paper that reports this interaction (PMID 9524259)
  • 11
  • Data Source:
  • HPRD (in vivo, two hybrid, in vitro)

IGF1R

PIK3R3

Gene Name insulin-like growth factor 1 receptor phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 59 interactors: AMY2A APP ARHGEF12 CAV1 CBL CRK CRKL CSK DOK4 DOK5 EEA1 EHD1 ESR1 FFAR2 GIPC1 GNAI1 GNAI2 GNB2L1 GRB10 GRB14 IGF1 IGF2 IGFBP3 INS INSR IRS1 IRS2 IRS4 ITGB1 JAK1 JAK2 KCNIP3 KL KRT27 MAP3K5 MDM2 NEDD4 PIK3R1 PIK3R2 PIK3R3 PRKCD PRKD1 PTPN1 PTPN11 RASA1 RPL11 SH2B1 SHC1 SOCS1 SOCS2 SOCS3 SRC STAT3 UBC VAV3 YWHAB YWHAE YWHAG YWHAZ 38 interactors: ABCB6 AMBP AXL DARS DRAP1 DSN1 EGFR ERBB2 ERBB3 ESR1 FBN3 FGB FSD2 GC IGF1R INSR IRS1 IRS2 KARS KHDRBS1 KIAA1377 KLC2 L3MBTL3 LUC7L2 MBIP MICAL1 ORM1 PDGFRB PIK3CA PSME1 QARS RB1 RING1 SERF1A TEC TRIM54 TRMT2A VBP1
Entrez ID 3480 8503
HPRD ID 00932 05831
Ensembl ID ENSG00000140443 ENSG00000117461
Uniprot IDs C9J5X1 P08069 F6TDL0 Q8N381 Q92569
PDB IDs 1IGR 1JQH 1K3A 1M7N 1P4O 2OJ9 2ZM3 3D94 3F5P 3I81 3LVP 3LW0 3NW5 3NW6 3NW7 3O23 3QQU
Enriched GO Terms of Interacting Partners?
Tagcloud ?
12q  12q21  14q31  15q25  16q23  18p  19q13  20p12  20pq  20q12  21q21  3p14  4pq  5p14  5q14  6p12  7p12  8q23  cardia  cdkn2  fist  gej  mlvi2  mts1  nrasl3  parentheses  ptpn1  rca1  xpq  xq25 
akt  carcinogenesis  diagnostic  downregulated  elucidating  hcc  hepatocellular  insights  invasion  inversely  investigations  lead  malignancy  markedly  micrornas  migration  mir  mirnas  mtor  negatively  phosphoinositide  regulating  repressing  strategies  suppressed  suppression  taken  tissues  underlying 
Tagcloud (Difference) ?
12q  12q21  14q31  15q25  16q23  18p  19q13  20p12  20pq  20q12  21q21  3p14  4pq  5p14  5q14  6p12  7p12  8q23  cardia  cdkn2  fist  gej  mlvi2  mts1  nrasl3  parentheses  ptpn1  rca1  xpq  xq25 
akt  carcinogenesis  diagnostic  downregulated  elucidating  hcc  hepatocellular  insights  invasion  inversely  investigations  lead  malignancy  markedly  micrornas  migration  mir  mirnas  mtor  negatively  phosphoinositide  regulating  repressing  strategies  suppressed  suppression  taken  tissues  underlying 
Tagcloud (Intersection) ?