IGF1R and MAP3K5

  • Number of citations of the paper that reports this interaction (PMID 12556535)
  • 12
  • Data Source:
  • HPRD (in vitro, in vivo)

IGF1R

MAP3K5

Gene Name insulin-like growth factor 1 receptor mitogen-activated protein kinase kinase kinase 5
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 59 interactors: AMY2A APP ARHGEF12 CAV1 CBL CRK CRKL CSK DOK4 DOK5 EEA1 EHD1 ESR1 FFAR2 GIPC1 GNAI1 GNAI2 GNB2L1 GRB10 GRB14 IGF1 IGF2 IGFBP3 INS INSR IRS1 IRS2 IRS4 ITGB1 JAK1 JAK2 KCNIP3 KL KRT27 MAP3K5 MDM2 NEDD4 PIK3R1 PIK3R2 PIK3R3 PRKCD PRKD1 PTPN1 PTPN11 RASA1 RPL11 SH2B1 SHC1 SOCS1 SOCS2 SOCS3 SRC STAT3 UBC VAV3 YWHAB YWHAE YWHAG YWHAZ 50 interactors: AKT1 AKT2 ARRB1 ARRB2 CDC25A CDKN1A CREBBP DAB2IP DAXX DMD DUSP19 EIF2AK2 EP300 ERN1 GADD45B GEMIN5 GLRX GSTM1 HSPA1A IGF1R JAK2 MAP2K4 MAP2K6 MAP2K7 MAP3K2 MAP3K3 MAP3K6 MAP3K7 MAPK8IP3 MBP NEDD4 NEDD4L PDCD6 PPP3R1 PPP5C PTPN11 QARS RAF1 SFN TNNT2 TPD52L1 TRAF2 TRAF5 TRAF6 TXN USP9X YWHAE YWHAH YWHAQ YWHAZ
Entrez ID 3480 4217
HPRD ID 00932 03904
Ensembl ID ENSG00000140443 ENSG00000197442
Uniprot IDs C9J5X1 P08069 Q99683
PDB IDs 1IGR 1JQH 1K3A 1M7N 1P4O 2OJ9 2ZM3 3D94 3F5P 3I81 3LVP 3LW0 3NW5 3NW6 3NW7 3O23 3QQU 2CLQ 3VW6 4BF2 4BHN 4BIB 4BIC 4BID 4BIE
Enriched GO Terms of Interacting Partners?
Tagcloud ?
12q  12q21  14q31  15q25  16q23  18p  19q13  20p12  20pq  20q12  21q21  3p14  4pq  5p14  5q14  6p12  7p12  8q23  cardia  cdkn2  fist  gej  mlvi2  mts1  nrasl3  parentheses  ptpn1  rca1  xpq  xq25 
199a2  angptl2  awry  chondrosarcoma  cmet  discovering  dnm3  evenly  fibrosarcoma  flt1  flt4  foxl1  genetics  gli1  hif1alpha  hmga2  kdr  liposarcoma  mdk  med12  muc4  mycn  osteocytes  pcsk1  relentless  sarcoma  tek  tie1  yeats4 
Tagcloud (Difference) ?
12q  12q21  14q31  15q25  16q23  18p  19q13  20p12  20pq  20q12  21q21  3p14  4pq  5p14  5q14  6p12  7p12  8q23  cardia  cdkn2  fist  gej  mlvi2  mts1  nrasl3  parentheses  ptpn1  rca1  xpq  xq25 
199a2  angptl2  awry  chondrosarcoma  cmet  discovering  dnm3  evenly  fibrosarcoma  flt1  flt4  foxl1  genetics  gli1  hif1alpha  hmga2  kdr  liposarcoma  mdk  med12  muc4  mycn  osteocytes  pcsk1  relentless  sarcoma  tek  tie1  yeats4 
Tagcloud (Intersection) ?