IGF1R and IGF2

  • Number of citations of the paper that reports this interaction (PMID 9972281)
  • 25
  • Data Source:
  • HPRD (in vivo)

IGF1R

IGF2

Gene Name insulin-like growth factor 1 receptor insulin-like growth factor 2
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • DNA methylation (variation) ( 23725790)
  • Femoral neck bone geometry and menarche (age at onset) ( 23593202)
  • Prostate cancer ( 19767753)
Protein-Protein Interactions 59 interactors: AMY2A APP ARHGEF12 CAV1 CBL CRK CRKL CSK DOK4 DOK5 EEA1 EHD1 ESR1 FFAR2 GIPC1 GNAI1 GNAI2 GNB2L1 GRB10 GRB14 IGF1 IGF2 IGFBP3 INS INSR IRS1 IRS2 IRS4 ITGB1 JAK1 JAK2 KCNIP3 KL KRT27 MAP3K5 MDM2 NEDD4 PIK3R1 PIK3R2 PIK3R3 PRKCD PRKD1 PTPN1 PTPN11 RASA1 RPL11 SH2B1 SHC1 SOCS1 SOCS2 SOCS3 SRC STAT3 UBC VAV3 YWHAB YWHAE YWHAG YWHAZ 22 interactors: BAG6 FAF1 GPC3 IDE IGF1R IGF2R IGFBP1 IGFBP2 IGFBP3 IGFBP4 IGFBP5 IGFBP6 IGFBP7 INSR NMRK2 NOV PCSK4 PLG RBPMS TF VTN WISP2
Entrez ID 3480 3481
HPRD ID 00932 00939
Ensembl ID ENSG00000140443 ENSG00000167244
Uniprot IDs C9J5X1 P08069 P01344
PDB IDs 1IGR 1JQH 1K3A 1M7N 1P4O 2OJ9 2ZM3 3D94 3F5P 3I81 3LVP 3LW0 3NW5 3NW6 3NW7 3O23 3QQU 1GF2 1IGL 2L29 2V5P 3E4Z 3KR3
Enriched GO Terms of Interacting Partners?
Tagcloud ?
12q  12q21  14q31  15q25  16q23  18p  19q13  20p12  20pq  20q12  21q21  3p14  4pq  5p14  5q14  6p12  7p12  8q23  cardia  cdkn2  fist  gej  mlvi2  mts1  nrasl3  parentheses  ptpn1  rca1  xpq  xq25 
affects  biological  blast  carrying  cdna  cecum  crossed  deleted  disrupted  excess  exclusively  igf2r  involve  mannose  must  organ  organs  overexpressing  paternal  phenotypes  proteolytic  sdeltaigf2r  sigf2r  slow  solely  soluble  stomach  transgenics  transmembrane 
Tagcloud (Difference) ?
12q  12q21  14q31  15q25  16q23  18p  19q13  20p12  20pq  20q12  21q21  3p14  4pq  5p14  5q14  6p12  7p12  8q23  cardia  cdkn2  fist  gej  mlvi2  mts1  nrasl3  parentheses  ptpn1  rca1  xpq  xq25 
affects  biological  blast  carrying  cdna  cecum  crossed  deleted  disrupted  excess  exclusively  igf2r  involve  mannose  must  organ  organs  overexpressing  paternal  phenotypes  proteolytic  sdeltaigf2r  sigf2r  slow  solely  soluble  stomach  transgenics  transmembrane 
Tagcloud (Intersection) ?