IGF1R and IGF1

  • Number of citations of the paper that reports this interaction (PMID 1852007)
  • 19

IGF1R

IGF1

Gene Name insulin-like growth factor 1 receptor insulin-like growth factor 1 (somatomedin C)
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Fasting glucose-related traits ( 20081858)
  • Fasting insulin-related traits ( 20081858)
  • Fasting insulin-related traits (interaction with BMI) ( 22581228)
  • Height ( 19893584 20189936)
  • Thiazide-induced adverse metabolic effects in hypertensive patients ( 23400010)
Protein-Protein Interactions 59 interactors: AMY2A APP ARHGEF12 CAV1 CBL CRK CRKL CSK DOK4 DOK5 EEA1 EHD1 ESR1 FFAR2 GIPC1 GNAI1 GNAI2 GNB2L1 GRB10 GRB14 IGF1 IGF2 IGFBP3 INS INSR IRS1 IRS2 IRS4 ITGB1 JAK1 JAK2 KCNIP3 KL KRT27 MAP3K5 MDM2 NEDD4 PIK3R1 PIK3R2 PIK3R3 PRKCD PRKD1 PTPN1 PTPN11 RASA1 RPL11 SH2B1 SHC1 SOCS1 SOCS2 SOCS3 SRC STAT3 UBC VAV3 YWHAB YWHAE YWHAG YWHAZ 16 interactors: CTSB E2F1 IDE IGF1R IGFALS IGFBP1 IGFBP2 IGFBP3 IGFBP4 IGFBP5 IGFBP6 IGFBP7 IGSF1 NOV TF WISP2
Entrez ID 3480 3479
HPRD ID 00932 00936
Ensembl ID ENSG00000140443 ENSG00000017427
Uniprot IDs C9J5X1 P08069 P05019 Q13429 Q59GC5 Q5U743
PDB IDs 1IGR 1JQH 1K3A 1M7N 1P4O 2OJ9 2ZM3 3D94 3F5P 3I81 3LVP 3LW0 3NW5 3NW6 3NW7 3O23 3QQU 1B9G 1BQT 1GF1 1GZR 1GZY 1GZZ 1H02 1H59 1IMX 1PMX 1TGR 1WQJ 2DSP 2DSQ 2DSR 2GF1 3GF1 3LRI
Enriched GO Terms of Interacting Partners?
Tagcloud ?
12q  12q21  14q31  15q25  16q23  18p  19q13  20p12  20pq  20q12  21q21  3p14  4pq  5p14  5q14  6p12  7p12  8q23  cardia  cdkn2  fist  gej  mlvi2  mts1  nrasl3  parentheses  ptpn1  rca1  xpq  xq25 
alphair3  augmenting  blastocyst  blastocysts  cytoplasm  embryo  embryos  entirely  fallopian  immunocytochemistry  immunoreactive  implantation  inner  intense  ivf  lining  maternal  maternally  midcycle  mimicking  paracrine  preimplantation  reproductive  supplementation  transcripts  tubal  tube  uterus 
Tagcloud (Difference) ?
12q  12q21  14q31  15q25  16q23  18p  19q13  20p12  20pq  20q12  21q21  3p14  4pq  5p14  5q14  6p12  7p12  8q23  cardia  cdkn2  fist  gej  mlvi2  mts1  nrasl3  parentheses  ptpn1  rca1  xpq  xq25 
alphair3  augmenting  blastocyst  blastocysts  cytoplasm  embryo  embryos  entirely  fallopian  immunocytochemistry  immunoreactive  implantation  inner  intense  ivf  lining  maternal  maternally  midcycle  mimicking  paracrine  preimplantation  reproductive  supplementation  transcripts  tubal  tube  uterus 
Tagcloud (Intersection) ?