IHO1 and GLRX3

Number of citations of the paper that reports this interaction (PubMedID 27107012)
72

Data Source:
BioGRID (two hybrid)

		IHO1	GLRX3
Description		interactor of HORMAD1 1	glutaredoxin 3
Image		No pdb structure
GO Annotations	Cellular Component	Condensed Nuclear Chromosome Chromosome	Nucleus Cytoplasm Cytosol Cell Cortex Z Disc Dendrite Iron-sulfur Cluster Assembly Complex
	Molecular Function	Protein Binding	RNA Binding Protein Kinase C Binding Protein Binding Identical Protein Binding Metal Ion Binding Iron-sulfur Cluster Binding
	Biological Process	DNA Recombination Homologous Chromosome Pairing At Meiosis Spermatogenesis Cell Differentiation Meiotic DNA Double-strand Break Formation Oogenesis Meiotic Cell Cycle Regulation Of Homologous Chromosome Segregation	Regulation Of The Force Of Heart Contraction Intracellular Iron Ion Homeostasis Negative Regulation Of Cardiac Muscle Hypertrophy Iron-sulfur Cluster Assembly [2Fe-2S] Cluster Assembly Cell Redox Homeostasis
Pathways			Iron uptake and transport
Drugs
Diseases
GWAS			Alcohol dependence ( 26365420) Colorectal cancer ( 34062886) Copper levels ( 26025379) Epstein-Barr virus copy number in lymphoblastoid cell lines ( 28654678) HIV-1 susceptibility ( 21160409) Mean corpuscular volume ( 32888494) Response to (pegylated) interferon in HBeAg-negative hepatitis B ( 30715261) Sleep end time ( 33075057) Triglyceride levels x short total sleep time interaction (1df test) ( 31719535) Triglyceride levels x short total sleep time interaction (2df test) ( 31719535)
Interacting Genes		78 interacting genes: ABI2 ABI3 ADAMTS12 AIRIM AQP1 ARHGEF9 ATP6V0D1 BCL6 BOLA2 BOLA2B CARD9 CCDC120 CCDC57 CDC23 CFAP206 COX5B DGCR6 DVL2 DYNLL1 DYNLL2 EAF2 EFHC1 EXOC8 FAM124A FAM124B FANCG FANCL FASLG FHL3 FKBP6 GEM GLRX3 GLYCTK GOLGA2 GRAP2 GYS1 HEXIM2 HINFP IQUB KANK2 KIF9 KIFC3 KLC3 KLHL11 LMO2 LNX1 LONRF1 MAGEB4 MAGOHB MAPK9 MID2 MRFAP1L1 MVP MYO15B NEK6 NFKBID NGB PICK1 POLR1C PRKAB2 PRR34 RABGEF1 RAD51D RHOBTB3 RUNX1T1 SDCBP SMARCB1 STK25 TNS2 TRIM14 TRIM42 TTC19 USP2 USP20 ZGPAT ZKSCAN3 ZNF417 ZNF688	99 interacting genes: ADAMTSL3 ADAMTSL4 ALKBH3 BCL6 BOLA2 BOLA2B BOLA3 CA9 CBLB CCHCR1 CEBPA CERCAM CGGBP1 CIAPIN1 COL8A1 DANCR EFEMP2 ERBB2 FAM118A FRA10AC1 GATA1 GMCL1 GNG13 GRN HEXD HSD3B7 IHO1 IKZF1 IL10 IRX6 KLHDC9 KRT31 KRT38 KRTAP1-3 KRTAP10-1 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-8 KRTAP10-9 KRTAP12-3 KRTAP13-1 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP4-7 KRTAP5-11 KRTAP5-3 KRTAP5-6 KRTAP5-9 KRTAP9-2 KRTAP9-3 KRTAP9-8 LCE2D LNX1 LNX2 LRIG1 MAP3K3 MAPK6 MAPKBP1 MDFI METAP1 MOXD1 NADK NOTCH2NLA NTF4 OLFM3 PCSK5 PFDN5 PLEKHG4B PLSCR1 PRKCQ PRKCZ RCOR3 RECK RGS20 SMARCC1 SOX7 STAU1 STRA6 TCF4 TCL1B TLE5 TMEM25 TRAF1 TRIM36 TRIM42 UGP2 ZBTB44 ZNF124 ZNF148 ZNF23 ZNF426 ZNF490 ZNF512B ZNF544 ZNF774
Entrez ID		339834	10539
HPRD ID		14172	10153
Ensembl ID		ENSG00000173421	ENSG00000108010
Uniprot IDs		B4DZP6 Q8IYA8	A0A140VJK1 O76003
PDB IDs			2DIY 2WZ9 2YAN 3ZYW
Enriched GO Terms of Interacting Partners?		Protein Binding Cytoplasm Identical Protein Binding [2Fe-2S] Cluster Assembly Iron-sulfur Cluster Assembly Complex Negative Regulation Of Mast Cell Cytokine Production Cytoskeleton Microtubule-based Process Regulation Of Cellular Senescence Microtubule Centrosome Iron-sulfur Cluster Assembly Intracellular Iron Ion Homeostasis	Intermediate Filament Keratin Filament Hair Cycle Iron-sulfur Cluster Assembly Protein Binding Iron-sulfur Cluster Assembly Complex Identical Protein Binding
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