IHO1 and GYS1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid, two hybrid)

		IHO1	GYS1
Description		interactor of HORMAD1 1	glycogen synthase 1
Image		No pdb structure
GO Annotations	Cellular Component	Condensed Nuclear Chromosome Chromosome	Cytoplasm Cytosol Membrane Inclusion Body
	Molecular Function	Protein Binding	Catalytic Activity Alpha-1,4-glucan Glucosyltransferase (UDP-glucose Donor) Activity Protein Binding D-glucose Binding Transferase Activity Glycosyltransferase Activity Glycogen Synthase Activity, Transferring Glucose-1-phosphate
	Biological Process	DNA Recombination Homologous Chromosome Pairing At Meiosis Spermatogenesis Cell Differentiation Meiotic DNA Double-strand Break Formation Oogenesis Meiotic Cell Cycle Regulation Of Homologous Chromosome Segregation	Glycogen Metabolic Process Glycogen Biosynthetic Process Heart Development
Pathways			Glycogen synthesis Myoclonic epilepsy of Lafora Glycogen storage disease type XV (GYG1) Glycogen storage disease type 0 (muscle GYS1)
Drugs
Diseases			Glycogen storage diseases (GSD), including: von Gierke disease (GSD type Ia); Pompe disease (GSD type II); Cori disease, Forbe disease (GSD type III); Andersen disease (GSD type IV); McArdle disease (GSD type V); Hers disease (GSD type VI); Tarui disease (GSD type VII); Phosphorylase kinase deficiency (GSD type IX); Fanconi-Bickel syndrome (GSD type XI); Glycogen synthase deficiency (GSD type 0)
GWAS
Interacting Genes		78 interacting genes: ABI2 ABI3 ADAMTS12 AIRIM AQP1 ARHGEF9 ATP6V0D1 BCL6 BOLA2 BOLA2B CARD9 CCDC120 CCDC57 CDC23 CFAP206 COX5B DGCR6 DVL2 DYNLL1 DYNLL2 EAF2 EFHC1 EXOC8 FAM124A FAM124B FANCG FANCL FASLG FHL3 FKBP6 GEM GLRX3 GLYCTK GOLGA2 GRAP2 GYS1 HEXIM2 HINFP IQUB KANK2 KIF9 KIFC3 KLC3 KLHL11 LMO2 LNX1 LONRF1 MAGEB4 MAGOHB MAPK9 MID2 MRFAP1L1 MVP MYO15B NEK6 NFKBID NGB PICK1 POLR1C PRKAB2 PRR34 RABGEF1 RAD51D RHOBTB3 RUNX1T1 SDCBP SMARCB1 STK25 TNS2 TRIM14 TRIM42 TTC19 USP2 USP20 ZGPAT ZKSCAN3 ZNF417 ZNF688	43 interacting genes: AIMP2 APP BEND7 CCDC33 CDCA8 CLVS2 CRX CSNK2A1 EFHC2 FAM228A GSK3B GYG1 GYG2 HOXB6 HOXC8 IHO1 INCA1 KATNBL1 KLF1 KLF4 MAPKAPK5 MEOX1 NDUFB7 NHLRC1 PCYT1A PINX1 PLAGL2 PNMA5 PRKACA RBM48 SNIP1 SORBS3 SUMO2 TFAP2D TLE5 WASHC1 ZBTB33 ZNF212 ZNF326 ZNF474 ZNF552 ZNF620 ZNF774
Entrez ID		339834	2997
HPRD ID		14172	00721
Ensembl ID		ENSG00000173421	ENSG00000104812
Uniprot IDs		B4DZP6 Q8IYA8	P13807
PDB IDs			7Q0B 7Q0S 7Q12 7Q13 7ZBN 8CVX 8CVY 8CVZ
Enriched GO Terms of Interacting Partners?		Protein Binding Cytoplasm Identical Protein Binding [2Fe-2S] Cluster Assembly Iron-sulfur Cluster Assembly Complex Negative Regulation Of Mast Cell Cytokine Production Cytoskeleton Microtubule-based Process Regulation Of Cellular Senescence Microtubule Centrosome Iron-sulfur Cluster Assembly Intracellular Iron Ion Homeostasis	Nucleus Regulation Of Transcription By RNA Polymerase II Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of DNA-templated Transcription Regulation Of Primary Metabolic Process Regulation Of RNA Biosynthetic Process Glycogenin Glucosyltransferase Activity Regulation Of Macromolecule Metabolic Process DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Glycogen Biosynthetic Process Glycogen Metabolic Process Regulation Of RNA Metabolic Process DNA Binding Polysaccharide Biosynthetic Process Protein Binding Regulation Of Macromolecule Biosynthetic Process DNA-binding Transcription Factor Activity Energy Reserve Metabolic Process Polysaccharide Metabolic Process Regulation Of Metabolic Process Regulation Of Gene Expression Energy Derivation By Oxidation Of Organic Compounds Regulation Of Protein Ubiquitination Regulation Of Protein Metabolic Process Cellular Response To Endothelin Positive Regulation Of Apoptotic Process Regulation Of Post-translational Protein Modification Response To Endothelin Positive Regulation Of Programmed Cell Death Regulation Of Apoptotic Signaling Pathway Wnt Signaling Pathway RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Positive Regulation Of Neuron Apoptotic Process DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Positive Regulation Of Transcription By RNA Polymerase II Cellular Response To Laminar Fluid Shear Stress Regulation Of Cell Cycle Generation Of Precursor Metabolites And Energy Positive Regulation Of Protein Export From Nucleus
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?