IHO1 and ATP6V0D1

Number of citations of the paper that reports this interaction (PubMedID 27107012)
72

Data Source:
BioGRID (two hybrid)

		IHO1	ATP6V0D1
Description		interactor of HORMAD1 1	ATPase H+ transporting V0 subunit d1
Image		No pdb structure
GO Annotations	Cellular Component	Condensed Nuclear Chromosome Chromosome	Vacuolar Proton-transporting V-type ATPase, V0 Domain Lysosome Lysosomal Membrane Early Endosome Centrosome Synaptic Vesicle Endosome Membrane Membrane Apical Plasma Membrane Vacuolar Proton-transporting V-type ATPase Complex Clathrin-coated Vesicle Membrane Phagocytic Vesicle Membrane Synaptic Vesicle Membrane Cytoplasmic Vesicle Protein-containing Complex Proton-transporting V-type ATPase Complex Proton-transporting V-type ATPase, V0 Domain Plasma Membrane Proton-transporting V-type ATPase Complex Axon Terminus Extracellular Exosome
	Molecular Function	Protein Binding	Protein Binding Protein-containing Complex Binding Proton-transporting ATPase Activity, Rotational Mechanism
	Biological Process	DNA Recombination Homologous Chromosome Pairing At Meiosis Spermatogenesis Cell Differentiation Meiotic DNA Double-strand Break Formation Oogenesis Meiotic Cell Cycle Regulation Of Homologous Chromosome Segregation	Monoatomic Ion Transport Intracellular Iron Ion Homeostasis Vacuolar Transport Vacuolar Acidification Regulation Of Macroautophagy Cell Projection Organization Cellular Response To Increased Oxygen Levels Homeostatic Process Cilium Assembly Synaptic Vesicle Lumen Acidification Proton Transmembrane Transport
Pathways			ROS and RNS production in phagocytes XBP1(S) activates chaperone genes Insulin receptor recycling Transferrin endocytosis and recycling Amino acids regulate mTORC1 Ion channel transport Regulation of MITF-M-dependent genes involved in lysosome biogenesis and autophagy
Drugs			Tiludronic acid
Diseases
GWAS			Disease progression in age-related macular degeneration ( 29346644) Empathy quotient ( 29527006) Medication use (thyroid preparations) ( 31015401) Refractive error ( 32231278)
Interacting Genes		78 interacting genes: ABI2 ABI3 ADAMTS12 AIRIM AQP1 ARHGEF9 ATP6V0D1 BCL6 BOLA2 BOLA2B CARD9 CCDC120 CCDC57 CDC23 CFAP206 COX5B DGCR6 DVL2 DYNLL1 DYNLL2 EAF2 EFHC1 EXOC8 FAM124A FAM124B FANCG FANCL FASLG FHL3 FKBP6 GEM GLRX3 GLYCTK GOLGA2 GRAP2 GYS1 HEXIM2 HINFP IQUB KANK2 KIF9 KIFC3 KLC3 KLHL11 LMO2 LNX1 LONRF1 MAGEB4 MAGOHB MAPK9 MID2 MRFAP1L1 MVP MYO15B NEK6 NFKBID NGB PICK1 POLR1C PRKAB2 PRR34 RABGEF1 RAD51D RHOBTB3 RUNX1T1 SDCBP SMARCB1 STK25 TNS2 TRIM14 TRIM42 TTC19 USP2 USP20 ZGPAT ZKSCAN3 ZNF417 ZNF688	10 interacting genes: ADRB2 ATXN1 DMRT3 GATA1 IHO1 IKZF3 LIG4 RBPMS TLE5 TLX3
Entrez ID		339834	9114
HPRD ID		14172	06121
Ensembl ID		ENSG00000173421	ENSG00000159720
Uniprot IDs		B4DZP6 Q8IYA8	P61421
PDB IDs			6WLW 6WM2 6WM3 6WM4 7U4T 7UNF
Enriched GO Terms of Interacting Partners?		Protein Binding Cytoplasm Identical Protein Binding [2Fe-2S] Cluster Assembly Iron-sulfur Cluster Assembly Complex Negative Regulation Of Mast Cell Cytokine Production Cytoskeleton Microtubule-based Process Regulation Of Cellular Senescence Microtubule Centrosome Iron-sulfur Cluster Assembly Intracellular Iron Ion Homeostasis	Regulation Of DNA-templated Transcription Regulation Of RNA Metabolic Process Cell Differentiation Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Developmental Process Regulation Of Developmental Process Neuron Fate Specification Regulation Of Nucleobase-containing Compound Metabolic Process Cellular Developmental Process Regulation Of Macromolecule Biosynthetic Process Regulation Of Systemic Arterial Blood Pressure By Norepinephrine-epinephrine Regulation Of Primary Metabolic Process Regulation Of Bone Mineralization Nucleus Regulation Of Multicellular Organismal Development Nucleobase-containing Compound Biosynthetic Process Regulation Of Gene Expression Transcription By RNA Polymerase II Positive Regulation Of Mini Excitatory Postsynaptic Potential Beta2-adrenergic Receptor Activity Leukocyte Differentiation Basophil Differentiation Eosinophil Fate Commitment Regulation Of Cell Development Mononuclear Cell Differentiation DNA Binding Regulation Of Primitive Erythrocyte Differentiation Regulation Of Cell Differentiation Establishment Of Integrated Proviral Latency Establishment Of Viral Latency Adult Locomotory Behavior Cell Fate Specification Regulation Of Ossification DNA-templated Transcription Norepinephrine-epinephrine-mediated Vasodilation Involved In Regulation Of Systemic Arterial Blood Pressure Beta-adrenergic Receptor Activity Norepinephrine Binding Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Metabolic Process Identical Protein Binding System Development Sequence-specific DNA Binding Primitive Erythrocyte Differentiation Regulation Of Definitive Erythrocyte Differentiation DNA Ligase (ATP) Activity DNA Ligase IV Complex Pro-B Cell Differentiation T Cell Receptor V(D)J Recombination
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