IHO1 and ARHGEF9

Number of citations of the paper that reports this interaction (PubMedID 27107012)
72

Data Source:
BioGRID (two hybrid)

		IHO1	ARHGEF9
Description		interactor of HORMAD1 1	Cdc42 guanine nucleotide exchange factor 9
Image		No pdb structure
GO Annotations	Cellular Component	Condensed Nuclear Chromosome Chromosome	Cytoplasm Cytosol Postsynaptic Density Synapse GABA-ergic Synapse Postsynaptic Specialization
	Molecular Function	Protein Binding	Guanyl-nucleotide Exchange Factor Activity Protein Binding
	Biological Process	DNA Recombination Homologous Chromosome Pairing At Meiosis Spermatogenesis Cell Differentiation Meiotic DNA Double-strand Break Formation Oogenesis Meiotic Cell Cycle Regulation Of Homologous Chromosome Segregation	Regulation Of Small GTPase Mediated Signal Transduction Regulation Of Postsynaptic Specialization Assembly
Pathways			NRAGE signals death through JNK G alpha (12/13) signalling events CDC42 GTPase cycle RHOQ GTPase cycle GABA receptor activation GABA receptor activation
Drugs
Diseases			Hyperekplexia Early infantile epileptic encephalopathy; Ohtahara syndrome
GWAS			Male-pattern baldness ( 28196072)
Interacting Genes		78 interacting genes: ABI2 ABI3 ADAMTS12 AIRIM AQP1 ARHGEF9 ATP6V0D1 BCL6 BOLA2 BOLA2B CARD9 CCDC120 CCDC57 CDC23 CFAP206 COX5B DGCR6 DVL2 DYNLL1 DYNLL2 EAF2 EFHC1 EXOC8 FAM124A FAM124B FANCG FANCL FASLG FHL3 FKBP6 GEM GLRX3 GLYCTK GOLGA2 GRAP2 GYS1 HEXIM2 HINFP IQUB KANK2 KIF9 KIFC3 KLC3 KLHL11 LMO2 LNX1 LONRF1 MAGEB4 MAGOHB MAPK9 MID2 MRFAP1L1 MVP MYO15B NEK6 NFKBID NGB PICK1 POLR1C PRKAB2 PRR34 RABGEF1 RAD51D RHOBTB3 RUNX1T1 SDCBP SMARCB1 STK25 TNS2 TRIM14 TRIM42 TTC19 USP2 USP20 ZGPAT ZKSCAN3 ZNF417 ZNF688	12 interacting genes: BCL6 CDC42 CFTR FAM90A1 GPHN IHO1 KHDRBS1 PLEKHA5 SMURF1 TBC1D22B TFIP11 TSGA10IP
Entrez ID		339834	23229
HPRD ID		14172	02337
Ensembl ID		ENSG00000173421	ENSG00000131089
Uniprot IDs		B4DZP6 Q8IYA8	A0A1B0GWI5 A0A5F9ZHY9 A0A5F9ZI31 B1AMR3 O43307
PDB IDs			2YSQ
Enriched GO Terms of Interacting Partners?		Protein Binding Cytoplasm Identical Protein Binding [2Fe-2S] Cluster Assembly Iron-sulfur Cluster Assembly Complex Negative Regulation Of Mast Cell Cytokine Production Cytoskeleton Microtubule-based Process Regulation Of Cellular Senescence Microtubule Centrosome Iron-sulfur Cluster Assembly Intracellular Iron Ion Homeostasis
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