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CCDC36 and AQP1
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
CCDC36
AQP1
Gene Name
coiled-coil domain containing 36
aquaporin 1 (Colton blood group)
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Cytoplasm
Plasma Membrane
Integral Component Of Plasma Membrane
Brush Border
Basal Plasma Membrane
Basolateral Plasma Membrane
Apical Plasma Membrane
Symbiont-containing Vacuole
Symbiont-containing Vacuole Membrane
Brush Border Membrane
Nuclear Membrane
Sarcolemma
Axon Terminus
Apical Part Of Cell
Extracellular Vesicular Exosome
Molecular Function
Intracellular CGMP Activated Cation Channel Activity
Potassium Channel Activity
Water Transmembrane Transporter Activity
Protein Binding
Ammonium Transmembrane Transporter Activity
Potassium Ion Transmembrane Transporter Activity
Glycerol Transmembrane Transporter Activity
Water Channel Activity
Glycerol Channel Activity
Transmembrane Transporter Activity
Nitric Oxide Transmembrane Transporter Activity
Carbon Dioxide Transmembrane Transporter Activity
Ephrin Receptor Binding
Biological Process
Renal Water Homeostasis
Glomerular Filtration
Renal Water Transport
CGMP Biosynthetic Process
Potassium Ion Transport
Water Transport
Cell Volume Homeostasis
Cellular Water Homeostasis
Positive Regulation Of Lamellipodium Assembly
Positive Regulation Of Epithelial Cell Migration
Carbon Dioxide Transport
Ammonium Transport
Bicarbonate Transport
Glycerol Transport
Sensory Perception Of Pain
Cellular Homeostasis
Lateral Ventricle Development
Pancreatic Juice Secretion
Nitric Oxide Transport
Establishment Or Maintenance Of Actin Cytoskeleton Polarity
Cerebrospinal Fluid Secretion
Secretory Granule Organization
Cellular Response To Stress
Cellular Response To UV
Transepithelial Water Transport
Carbon Dioxide Transmembrane Transport
Wound Healing
Odontogenesis
Response To Drug
Hyperosmotic Salinity Response
Negative Regulation Of Apoptotic Process
Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Response To Estrogen
Lipid Digestion
Small Molecule Metabolic Process
Positive Regulation Of Angiogenesis
Positive Regulation Of Saliva Secretion
Positive Regulation Of Fibroblast Proliferation
Camera-type Eye Morphogenesis
Multicellular Organismal Water Homeostasis
Corticotropin Secretion
Transmembrane Transport
Renal Water Absorption
Cellular Response To Hydrogen Peroxide
Cellular Response To Inorganic Substance
Cellular Response To Mechanical Stimulus
Cellular Response To Copper Ion
Cellular Response To Mercury Ion
Cellular Response To Retinoic Acid
Cellular Response To CAMP
Cellular Response To Hypoxia
Cellular Response To Salt Stress
Cellular Hyperosmotic Response
Cellular Response To Dexamethasone Stimulus
Cellular Response To Nitric Oxide
Potassium Ion Transmembrane Transport
Metanephric Descending Thin Limb Development
Metanephric Proximal Straight Tubule Development
Metanephric Proximal Convoluted Tubule Segment 2 Development
Metanephric Glomerulus Vasculature Development
Ammonium Transmembrane Transport
Maintenance Of Symbiont-containing Vacuole By Host
Cation Transmembrane Transport
Pathways
O2/CO2 exchange in erythrocytes
Erythrocytes take up carbon dioxide and release oxygen
Vasopressin regulates renal water homeostasis via Aquaporins
Passive transport by Aquaporins
Erythrocytes take up oxygen and release carbon dioxide
Aquaporin-mediated transport
Drugs
Acetazolamide
Diseases
GWAS
Nephrolithiasis (
22396660
)
Protein-Protein Interactions
33 interactors:
ABI2
AQP1
C1orf109
CARD9
CDC23
COX5B
DGCR6
DYNLL1
DYNLL2
FAM124A
FANCL
FKBP6
GYS1
HEXIM2
IQUB
KANK2
KLC3
LMO2
LONRF1
MRFAP1L1
MVP
MYO15B
NEK6
NGB
POLR1C
PRKAB2
RUNX1T1
SDCBP
STK25
TRIM42
TTC19
USP2
USP20
42 interactors:
ADAMTSL4
CCDC136
CCDC36
CCDC57
CCDC85B
CEP44
CRTAC1
CSRNP1
EFEMP2
EPHB2
FOS
FSD2
IKZF2
IKZF3
KCTD17
KCTD9
KIAA1958
KRT31
KRT33B
KRT40
KRTAP10-3
KRTAP10-7
KRTAP4-12
KRTAP4-2
KRTAP9-2
MDFI
MID2
MTUS2
NBPF22P
NOTCH2NL
PICK1
RGS17
RGS20
RIMBP3
SIAH1
SPRY2
TCF4
TNK2
TRAF1
TRAF2
TRIM23
TRIP6
Entrez ID
339834
358
HPRD ID
14172
00140
Ensembl ID
ENSG00000173421
ENSG00000240583
Uniprot IDs
B4DZP6
Q8IYA8
B4DPF5
B4E3E3
P29972
PDB IDs
1FQY
1H6I
1IH5
Enriched GO Terms of Interacting Partners
?
Regulation Of Proteasomal Protein Catabolic Process
Apoptotic Process
Programmed Cell Death
Cell Death
Death
Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway
Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Positive Regulation Of Stress-activated MAPK Cascade
Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade
Regulation Of Organelle Organization
Organelle Organization
Regulation Of Cell Cycle
Regulation Of Phosphorylation
Regulation Of Protein Metabolic Process
Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Cell Cycle
Regulation Of Proteolysis
Regulation Of Protein Catabolic Process
Ammonium Transmembrane Transport
Positive Regulation Of Organelle Organization
Metanephric Descending Thin Limb Development
Metanephric Proximal Straight Tubule Development
Metanephric Proximal Convoluted Tubule Segment 2 Development
Maintenance Of Symbiont-containing Vacuole By Host
Transepithelial Water Transport
Synaptic Target Recognition
Regulation Of Mitotic Cell Cycle
Regulation Of Phosphorus Metabolic Process
Generation Of Precursor Metabolites And Energy
Regulation Of Stress-activated MAPK Cascade
Intrinsic Apoptotic Signaling Pathway
Regulation Of Cellular Component Organization
Regulation Of Cellular Protein Metabolic Process
Regulation Of Mitotic Metaphase/anaphase Transition
Regulation Of Metabolic Process
Negative Regulation Of Cell Cycle
Regulation Of Mitotic Cell Cycle Phase Transition
Positive Regulation Of Mitochondrion Organization
Cellular Response To Hydrogen Peroxide
Negative Regulation Of Cellular Metabolic Process
Negative Regulation Of Vitamin D Receptor Signaling Pathway
Carbon Dioxide Transmembrane Transport
Corticotropin Secretion
Intrinsic Apoptotic Signaling Pathway In Response To Hydrogen Peroxide
Establishment Or Maintenance Of Actin Cytoskeleton Polarity
Regulation Of Cell Cycle Phase Transition
Positive Regulation Of Signal Transduction
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Ammonium Transport
Proteasomal Protein Catabolic Process
Positive Regulation Of Intracellular Signal Transduction
Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Regulation Of Signaling
Positive Regulation Of Metabolic Process
Regulation Of Metabolic Process
Regulation Of Binding
Developmental Process
Regulation Of Gene Expression
Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway
Dendritic Spine Organization
Positive Regulation Of NF-kappaB Transcription Factor Activity
Positive Regulation Of Signal Transduction
Axonal Fasciculation
Embryonic Organ Morphogenesis
Regulation Of Signal Transduction
Signal Transduction
Regulation Of Protein Binding
Cell Differentiation
Regulation Of Cellular Process
Face Morphogenesis
Neuron Recognition
Regulation Of Apoptotic Process
Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway
Head Morphogenesis
Regulation Of Nitrogen Compound Metabolic Process
Signaling
Regulation Of Cell Death
Positive Regulation Of Cellular Metabolic Process
Regulation Of Extrinsic Apoptotic Signaling Pathway
Cell Communication
Negative Regulation Of Signaling
Face Development
Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Regulation Of Nucleocytoplasmic Transport
Cellular Response To Extracellular Stimulus
Embryonic Organ Development
I-kappaB Kinase/NF-kappaB Signaling
Negative Regulation Of Fat Cell Differentiation
Body Morphogenesis
DNA Methylation
TRIF-dependent Toll-like Receptor Signaling Pathway
Catenin Import Into Nucleus
Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition
Regulation Of Intracellular Signal Transduction
Termination Of G-protein Coupled Receptor Signaling Pathway
Positive Regulation Of Protein Binding
MyD88-independent Toll-like Receptor Signaling Pathway
Termination Of Signal Transduction
Toll-like Receptor 3 Signaling Pathway
Enzyme Linked Receptor Protein Signaling Pathway
Tagcloud
?
2cl
absorption
acclimation
bumetanide
circuit
cl
cotransporter
eel
exchanger
gn
governed
guanylin
hco3
intestine
isc
mi
ncc
nccbeta
nkcc
nkcc2beta
nullified
player
remainder
seawater
slc26a6
teleost
transporters
versa
vice
Tagcloud (Difference)
?
2cl
absorption
acclimation
bumetanide
circuit
cl
cotransporter
eel
exchanger
gn
governed
guanylin
hco3
intestine
isc
mi
ncc
nccbeta
nkcc
nkcc2beta
nullified
player
remainder
seawater
slc26a6
teleost
transporters
versa
vice
Tagcloud (Intersection)
?