HSPA4 and APPBP2

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		HSPA4	APPBP2
Gene Name		heat shock 70kDa protein 4	amyloid beta precursor protein (cytoplasmic tail) binding protein 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrion Cytosol Extracellular Vesicular Exosome	Nucleus Cytoplasm Microtubule Microtubule Associated Complex Cytoplasmic Vesicle Membrane
	Molecular Function	ATP Binding	Microtubule Motor Activity Protein Binding
	Biological Process	Response To Unfolded Protein Protein Import Into Mitochondrial Outer Membrane Chaperone-mediated Protein Complex Assembly	Intracellular Protein Transport Metabolic Process Intracellular Transport
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		58 interactors: AGTRAP APPBP2 BAG1 BAG2 BAG5 BRMS1 CALM1 CD40 CDC73 CDKN2A CSNK1A1 CSNK2A1 DDIT4 DNAJB1 DUSP1 EGFR ESR1 FANCC FES FKBP4 GATA1 GRPEL2 GSK3B GZMA HAP1 HDAC3 HNRNPD HSPBP1 IKBKG KPNA2 KRT18 MAPT NFKB1 NR3C2 OLR1 PHLDA1 PPP1CA PRKCB PRKCD PRKCG PRSS23 PSMD10 RAF1 REL RELA SMAD3 SOD1 ST13 STIP1 STUB1 SUGT1 TERT TIMM44 TOMM40 TRAF6 TTC1 UBE2L3 UBE3A	79 interactors: AHCY AIM2 AK3 ANKRD10 APP AR ARMCX5 C1orf50 C6orf226 CALM3 CCDC85C CCNL1 CDK16 CHMP5 CLCN1 CNTFR COL24A1 CORO2B CREB3 CSNK1G2 CTC1 DCD DHRS2 DPEP1 EID3 EPT1 ERO1L FAM19A4 FAM92A1 FSTL1 FXYD7 GALNT3 GCSAM GP9 GSTP1 HIPK4 HIST1H2AK HSPA4 KIF6 KLF11 KLHL35 LANCL2 LONRF3 LUC7L2 LUZP4 MFSD3 MGC34796 MLLT3 MUL1 NFYA NPRL3 PCSK5 PI4KAP2 PPP1R8 PRKAA2 PRKACB PYROXD2 RASSF5 RNF128 RNF34 RRS1 SELV SLC22A6 SLC25A23 SNX5 ST8SIA5 SYNRG SYT11 TAF11 TBL3 TCF25 UBE2R2 UGGT2 WAS WDR24 WNT5B ZC3H10 ZCCHC12 ZNF747
Entrez ID		3308	10513
HPRD ID		09025	05616
Ensembl ID			ENSG00000062725
Uniprot IDs		P34932	Q92624
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Cell Death Regulation Of Apoptotic Process Regulation Of Protein Metabolic Process Positive Regulation Of Signal Transduction Regulation Of Cellular Protein Metabolic Process Cellular Response To Organic Substance Negative Regulation Of Cell Death Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Positive Regulation Of Protein Metabolic Process Response To Organic Substance Regulation Of Signal Transduction Neurotrophin TRK Receptor Signaling Pathway Cell Death Death Neurotrophin Signaling Pathway Positive Regulation Of Cellular Metabolic Process Regulation Of Signaling Negative Regulation Of Protein Metabolic Process Positive Regulation Of Metabolic Process Negative Regulation Of Cellular Metabolic Process Response To Stress Cellular Response To Growth Factor Stimulus Protein Metabolic Process Positive Regulation Of Cellular Protein Metabolic Process Apoptotic Process Response To Growth Factor Cellular Response To Stimulus Programmed Cell Death Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Protein Modification Process Negative Regulation Of Signal Transduction Cellular Metabolic Process Signaling Response To Stimulus Cell Communication Regulation Of Metabolic Process Negative Regulation Of Signaling Positive Regulation Of Cell Death Cellular Protein Metabolic Process Signal Transduction Regulation Of Protein Phosphorylation Immune System Process Regulation Of Catalytic Activity Positive Regulation Of Cellular Biosynthetic Process Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cell Surface Receptor Signaling Pathway Negative Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death	Regulation Of Defense Response To Virus By Host Response To Stress Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Homocysteine Metabolic Process Cellular Response To Organic Substance
Tagcloud ?		competence cumulus damaged domestic fertility hfs2 hsf hsf1 hsp110 hsp40 hsp90a hsp90b hsph1 hsps machinery oocyte oocytes operational ovaries ovary pig preserve sows summer unexpectedly warm winter	10kb arhgap32 bcas3 breakpoints ccdc49 coamplification col14a1 coregulator ddx5 depdc6 deptor enpp2 hoxb9 lasp1 leukaemias nrip1 oprd1 painting pcgf2 phf20l1 plec1 skap1 taok1 tiam1 timm23 trps1 unamplified usp32 zmym4
Tagcloud (Difference) ?		competence cumulus damaged domestic fertility hfs2 hsf hsf1 hsp110 hsp40 hsp90a hsp90b hsph1 hsps machinery oocyte oocytes operational ovaries ovary pig preserve sows summer unexpectedly warm winter	10kb arhgap32 bcas3 breakpoints ccdc49 coamplification col14a1 coregulator ddx5 depdc6 deptor enpp2 hoxb9 lasp1 leukaemias nrip1 oprd1 painting pcgf2 phf20l1 plec1 skap1 taok1 tiam1 timm23 trps1 unamplified usp32 zmym4
Tagcloud (Intersection) ?