APPBP2 and CIBAR1

Number of citations of the paper that reports this interaction (PubMedID 19060904)
32

Data Source:
BioGRID (two hybrid)

		APPBP2	CIBAR1
Description		amyloid beta precursor protein binding protein 2	CBY1 interacting BAR domain containing 1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytoskeleton Microtubule Microtubule Associated Complex Membrane Cytoplasmic Vesicle Membrane Cul2-RING Ubiquitin Ligase Complex	Nucleus Cytoplasm Mitochondrion Mitochondrial Inner Membrane Centriole Microtubule Organizing Center Cytoskeleton Cilium Membrane Mitochondrial Crista Motile Cilium Ciliary Transition Zone Ciliary Basal Body Cell Projection Sperm Annulus Ciliary Base
	Molecular Function	Microtubule Motor Activity Protein Binding Ubiquitin-like Ligase-substrate Adaptor Activity	Protein Binding Phospholipid Binding
	Biological Process	Intracellular Protein Transport Protein Transport Protein Ubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Intracellular Transport	Inner Mitochondrial Membrane Organization Spermatogenesis Cell Projection Organization Cell Differentiation Limb Morphogenesis Positive Regulation Of Smoothened Signaling Pathway Cilium Assembly Membrane Organization Membrane Tubulation
Pathways
Drugs
Diseases
GWAS		Interleukin-6 levels ( 33517400) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Waist-hip ratio ( 28552196)
Interacting Genes		122 interacting genes: - AADAC ACTN1 AHCY AIM2 AK3 ALDH1L1 ANKRD10 APP AR ARMCX5 ASCC3 ATP13A1 BCL7A BIN2 C1orf50 CALM3 CCDC167 CCDC85C CCNL1 CDK16 CHMP5 CIBAR1 CLCN1 CNTFR COL24A1 CORO2B CREB3 CSNK1G2 CST2 CTC1 CYBA DCD DHRS2 DHX16 DOLK DPEP1 DPYS EID3 ERO1A FAM107A FSTL1 FXYD7 GALNT3 GCSAM GP9 GPRC5C GSTP1 H2AC15 HGFAC HIPK4 HSD3B7 HSPA4 ITGB4 ITGB5 KHK KIF6 KLF11 KLHL35 LANCL2 LONRF3 LUC7L2 LUZP4 MAN2B2 MCOLN1 MGAT4B MLLT3 MMP28 MRPL28 MSH2 MSLN MUL1 MYLK NFYA NHERF1 NPRL3 PCSK5 PEX39 PI4KAP2 PNPLA5 PPIL6 PPP1R8 PRKAA2 PRKACB PSAP PTCH1 PYROXD2 RAB7B RASSF5 RHEB RILPL1 RNF128 RNF34 RNGTT RRS1 SELENOI SELENOV SLC22A6 SLC25A23 SLC33A2 SLC7A10 SNX5 SPDYE2 SPDYE2B ST8SIA5 SYNRG SYT11 TAF11 TAFA4 TBL3 TCF25 TNP2 TRMT2A UBE2R2 UGGT2 WAS WDR24 WFIKKN1 WNT5B ZC3H10 ZCCHC12 ZNF747	4 interacting genes: APPBP2 CBY1 CBY2 SHANK3
Entrez ID		10513	137392
HPRD ID		05616	14061
Ensembl ID		ENSG00000062725	ENSG00000188343
Uniprot IDs		Q92624	A1XBS5
PDB IDs		8JAL 8JAQ 8JAR 8JAS 8JAU 8JAV	8CEG
Enriched GO Terms of Interacting Partners?		Protein Binding	Ciliary Membrane Cytoplasmic Vesicle Membrane Wnt Signaling Pathway Cilium Organization Plasma Membrane Bounded Cell Projection Organization Cilium Assembly Cell Projection Floor Plate Development Cell Projection Organization Organelle Assembly Guanylate Kinase-associated Protein Clustering Vocal Learning Negative Regulation Of Cytoskeleton Organization Negative Regulation Of Cell Volume Positive Regulation Of Glutamate Receptor Signaling Pathway Neuron Spine Postsynaptic Density Assembly Positive Regulation Of Long-term Neuronal Synaptic Plasticity AMPA Glutamate Receptor Clustering Synaptic Receptor Adaptor Activity Regulation Of Synapse Structural Plasticity Positive Regulation Of Synapse Structural Plasticity NMDA Glutamate Receptor Clustering GABAergic Neuron Differentiation Neurotransmitter-gated Ion Channel Clustering Regulation Of Glutamate Receptor Signaling Pathway Observational Learning Striatal Medium Spiny Neuron Differentiation Postsynaptic Specialization Assembly Negative Regulation Of Centrosome Duplication MKS Complex Filamin Binding Plasma Membrane Bounded Cell Projection Assembly Auditory Behavior Cell Projection Assembly Regulation Of Long-term Synaptic Depression Mechanosensory Behavior Cul2-RING Ubiquitin Ligase Complex Dendritic Spine Morphogenesis Cytoskeleton Postsynaptic Density Organization Brain Morphogenesis Vocalization Behavior Positive Regulation Of Long-term Synaptic Potentiation Proteasomal Protein Catabolic Process Postsynaptic Specialization Organization Regulation Of Long-term Neuronal Synaptic Plasticity Intracellular Protein Localization Positive Regulation Of Excitatory Postsynaptic Potential Regulation Of Cytoskeleton Organization
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