HSPA4 and PRSS23

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		HSPA4	PRSS23
Gene Name		heat shock 70kDa protein 4	protease, serine, 23
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrion Cytosol Extracellular Vesicular Exosome	Nucleus Extracellular Vesicular Exosome
	Molecular Function	ATP Binding	Serine-type Endopeptidase Activity
	Biological Process	Response To Unfolded Protein Protein Import Into Mitochondrial Outer Membrane Chaperone-mediated Protein Complex Assembly	Proteolysis
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		58 interactors: AGTRAP APPBP2 BAG1 BAG2 BAG5 BRMS1 CALM1 CD40 CDC73 CDKN2A CSNK1A1 CSNK2A1 DDIT4 DNAJB1 DUSP1 EGFR ESR1 FANCC FES FKBP4 GATA1 GRPEL2 GSK3B GZMA HAP1 HDAC3 HNRNPD HSPBP1 IKBKG KPNA2 KRT18 MAPT NFKB1 NR3C2 OLR1 PHLDA1 PPP1CA PRKCB PRKCD PRKCG PRSS23 PSMD10 RAF1 REL RELA SMAD3 SOD1 ST13 STIP1 STUB1 SUGT1 TERT TIMM44 TOMM40 TRAF6 TTC1 UBE2L3 UBE3A	25 interactors: ACTG1 APP B2M CHP1 EFNA3 FXR1 GRK6 HSPA4 MAPK8IP2 NCAPD3 NIPBL NOC4L ODF2L PDDC1 PDPK1 PHF23 PPIA RACGAP1 RECQL4 RPL4P5 SHMT1 SLC25A6 TCF12 TMEM222 TRAPPC4
Entrez ID		3308	11098
HPRD ID		09025	07149
Ensembl ID			ENSG00000150687
Uniprot IDs		P34932	B4E2J3 O95084
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Cell Death Regulation Of Apoptotic Process Regulation Of Protein Metabolic Process Positive Regulation Of Signal Transduction Regulation Of Cellular Protein Metabolic Process Cellular Response To Organic Substance Negative Regulation Of Cell Death Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Positive Regulation Of Protein Metabolic Process Response To Organic Substance Regulation Of Signal Transduction Neurotrophin TRK Receptor Signaling Pathway Cell Death Death Neurotrophin Signaling Pathway Positive Regulation Of Cellular Metabolic Process Regulation Of Signaling Negative Regulation Of Protein Metabolic Process Positive Regulation Of Metabolic Process Negative Regulation Of Cellular Metabolic Process Response To Stress Cellular Response To Growth Factor Stimulus Protein Metabolic Process Positive Regulation Of Cellular Protein Metabolic Process Apoptotic Process Response To Growth Factor Cellular Response To Stimulus Programmed Cell Death Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Protein Modification Process Negative Regulation Of Signal Transduction Cellular Metabolic Process Signaling Response To Stimulus Cell Communication Regulation Of Metabolic Process Negative Regulation Of Signaling Positive Regulation Of Cell Death Cellular Protein Metabolic Process Signal Transduction Regulation Of Protein Phosphorylation Immune System Process Regulation Of Catalytic Activity Positive Regulation Of Cellular Biosynthetic Process Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cell Surface Receptor Signaling Pathway Negative Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death	Platelet Activation Blood Coagulation Hemostasis Cell Differentiation Cellular Component Assembly Regulation Of Body Fluid Levels Organelle Organization Wound Healing Multicellular Organismal Development Generation Of Neurons Cell Activation Dendrite Development System Development Response To Stress Response To Wounding Neurogenesis Mating Behavior Nervous System Development Regulation Of Protein Localization Response To Stimulus Neuron Projection Development Cell Development Developmental Process Cytokinesis, Initiation Of Separation Actomyosin Contractile Ring Assembly Uncoating Of Virus Mating Anatomical Structure Development Neuron Development Retina Homeostasis Movement Of Cell Or Subcellular Component Cell Morphogenesis Involved In Neuron Differentiation Protein Targeting To Mitochondrion Protein Complex Assembly Regulation Of Cellular Localization Immune System Process Platelet Degranulation Negative Regulation Of Rho-dependent Protein Serine/threonine Kinase Activity Synaptic Growth At Neuromuscular Junction Active Induction Of Host Immune Response By Virus Mitotic Sister Chromatid Segregation Protein Localization To Mitochondrion Protein Folding Cognition Neuron Projection Morphogenesis Positive Regulation Of Cellular Protein Metabolic Process Neuron Differentiation Mitotic Nuclear Division Sister Chromatid Segregation Regulation Of Establishment Of Protein Localization
Tagcloud ?		competence cumulus damaged domestic fertility hfs2 hsf hsf1 hsp110 hsp40 hsp90a hsp90b hsph1 hsps machinery oocyte oocytes operational ovaries ovary pig preserve sows summer unexpectedly warm winter
Tagcloud (Difference) ?		competence cumulus damaged domestic fertility hfs2 hsf hsf1 hsp110 hsp40 hsp90a hsp90b hsph1 hsps machinery oocyte oocytes operational ovaries ovary pig preserve sows summer unexpectedly warm winter
Tagcloud (Intersection) ?