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ANXA5 and TINF2
Number of citations of the paper that reports this interaction (PubMedID
21044950
)
82
Data Source:
BioGRID
(two hybrid)
ANXA5
TINF2
Description
annexin A5
TERF1 interacting nuclear factor 2
Image
GO Annotations
Cellular Component
Extracellular Region
Cytoplasm
Cytosol
Focal Adhesion
External Side Of Plasma Membrane
Vesicle Membrane
Membrane
Extracellular Matrix
Sarcolemma
Extracellular Exosome
Endothelial Microparticle
Chromosome, Telomeric Region
Nuclear Telomere Cap Complex
Nucleus
Nucleoplasm
Chromosome
Perinucleolar Chromocenter
Nuclear Matrix
Nuclear Body
Shelterin Complex
Molecular Function
Phosphatidylserine Binding
Phospholipase Inhibitor Activity
Calcium Ion Binding
Protein Binding
Phospholipid Binding
Calcium-dependent Phospholipid Binding
DNA Binding
Protein Binding
Telomeric DNA Binding
Biological Process
Signal Transduction
Blood Coagulation
Hemostasis
Negative Regulation Of Apoptotic Process
Negative Regulation Of Coagulation
Telomere Capping
Telomere Assembly
Positive Regulation Of Telomere Maintenance
Negative Regulation Of Telomere Maintenance Via Telomerase
Negative Regulation Of Epithelial Cell Proliferation
Protein Localization To Chromosome, Telomeric Region
Regulation Of Telomere Maintenance Via Telomere Lengthening
Pathways
Platelet degranulation
Recognition and association of DNA glycosylase with site containing an affected pyrimidine
Cleavage of the damaged pyrimidine
Recognition and association of DNA glycosylase with site containing an affected purine
Recognition and association of DNA glycosylase with site containing an affected purine
Cleavage of the damaged purine
Cleavage of the damaged purine
Meiotic synapsis
Packaging Of Telomere Ends
Telomere Extension By Telomerase
Polymerase switching on the C-strand of the telomere
Processive synthesis on the C-strand of the telomere
Telomere C-strand (Lagging Strand) Synthesis
Telomere C-strand synthesis initiation
Removal of the Flap Intermediate from the C-strand
DNA Damage/Telomere Stress Induced Senescence
Inhibition of DNA recombination at telomere
Drugs
Fluocinolone acetonide
L-Alpha-Glycerophosphorylserine
L-thioproline
K201 free base
sn-glycero-3-phosphoethanolamine
1,4-Dideoxy-O2-Sulfo-Glucuronic Acid
N,O6-Disulfo-Glucosamine
1,4-Dideoxy-5-Dehydro-O2-Sulfo-Glucuronic Acid
Copper
Diseases
Revesz syndrome; Exudative retinopathy with bone marrow failure
GWAS
A body shape index (
34021172
)
Age at smoking initiation in chronic obstructive pulmonary disease (
21685187
)
Age-related cognitive decline (language) (slope of z-scores) (
30954325
)
Resting-state electroencephalogram vigilance (
29703947
)
Waist-hip index (
34021172
)
Waist-to-hip ratio adjusted for BMI (
34021172
)
Leukocyte telomere length (
31171785
)
Platelet count (
29403010
)
Interacting Genes
20 interacting genes:
ACTG1
APP
CEBPA
COL10A1
COL2A1
EED
EIF4G1
FDFT1
GSC2
IFNGR2
ITGB5
KDR
LAMC3
LINC01554
PPP2R1B
SUPT4H1
TERF1
TERF2
TERF2IP
TINF2
91 interacting genes:
ACD
ACOT7
ACTB
ADA
AFAP1L2
AIPL1
AK1
ANKMY2
ANXA4
ANXA5
ANXA8L1
APOBEC3F
APPL2
ARHGDIA
ARID3B
BAG3
BIN2
CALD1
CCDC43
CCDC9
CKB
CLK3
CPNE3
CRYGS
CSNK2A1
CTTN
DBN1
DCX
DHFR2
DPP3
EEF1D
EIF4B
ENO2
FAM131B
FERMT3
FKBP6
GAPDH
GNMT
HNMT
HOXA3
HSP90AB1
IPO5
KCTD17
LASP1
LDHA
LGALSL
LTA4H
MAP2K3
MTNR1B
NCDN
NOL3
NUDC
NUDCD2
OR2H1
PAGE2
PAK1IP1
PEX5
PFKP
PGM1
PGM2
PHPT1
PKM
PPP1R2
PPP6R3
PRKCB
REM2
RGS14
RPSA
SARS1
SCRN2
SIAH2
STUB1
SULT1C2
TAGLN
TBL1X
TERF1
TERF2
TFRC
TOMM34
TPP1
TRIM15
TRIM16
TRIP10
TUBB
TUBB4B
TXNDC17
UCHL1
VIPR1
YWHAG
ZFP36L1
ZNF790
Entrez ID
308
26277
HPRD ID
00568
16056
Ensembl ID
ENSG00000164111
ENSG00000092330
Uniprot IDs
P08758
V9HWE0
B4DFJ1
Q9BSI4
PDB IDs
1ANW
1ANX
1AVH
1AVR
1HAK
1HVD
1HVE
1HVF
1HVG
1SAV
2XO2
2XO3
6K22
6K25
8GYC
8H0J
8H9Z
3BQO
3BU8
5XYF
Enriched GO Terms of Interacting Partners
?
Shelterin Complex
Nuclear Telomere Cap Complex
Telomere Capping
Telomeric DNA Binding
Negative Regulation Of Chromosome Organization
Negative Regulation Of Telomere Maintenance
Positive Regulation Of Chromosome Organization
G-rich Strand Telomeric DNA Binding
Protein Localization To Chromosome, Telomeric Region
Negative Regulation Of Telomeric D-loop Disassembly
Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication
Negative Regulation Of DNA Recombination At Telomere
Positive Regulation Of Telomere Maintenance
Negative Regulation Of Telomere Maintenance Via Telomerase
RNA-templated DNA Biosynthetic Process
Negative Regulation Of Telomere Maintenance Via Telomere Lengthening
Telomere Maintenance
Negative Regulation Of DNA Biosynthetic Process
Regulation Of Telomere Maintenance
Regulation Of Chromosome Organization
Telomere Organization
Regulation Of Telomere Maintenance Via Telomerase
Negative Regulation Of DNA Metabolic Process
Positive Regulation Of Organelle Organization
Telomerase Activity
Protection From Non-homologous End Joining At Telomere
Regulation Of Telomere Maintenance Via Telomere Lengthening
Positive Regulation Of Cellular Component Organization
Telomeric D-loop Disassembly
Double-stranded Telomeric DNA Binding
Chromosome Organization
Chromosome, Telomeric Region
Telomeric Loop Disassembly
Telomere Maintenance In Response To DNA Damage
Chromosome
Regulation Of DNA Biosynthetic Process
DNA Biosynthetic Process
Multicellular Organismal-level Homeostasis
Regulation Of Cell Junction Assembly
Telomere Maintenance Via Telomerase
Protein Localization To Chromosome
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Positive Regulation Of DNA Metabolic Process
Epithelial Cell Maturation
Regulation Of Organelle Organization
Regulation Of Presynapse Organization
Regulation Of Presynapse Assembly
Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Mitotic Cell Cycle
Negative Regulation Of Macromolecule Metabolic Process
Cytosol
Extracellular Exosome
Cytoplasm
ADP Metabolic Process
Purine Ribonucleotide Catabolic Process
Ribonucleoside Diphosphate Metabolic Process
Glycolytic Process
ADP Catabolic Process
Purine Nucleotide Catabolic Process
Nucleoside Phosphate Catabolic Process
Nucleoside Diphosphate Metabolic Process
Purine Ribonucleoside Diphosphate Catabolic Process
Ribonucleoside Diphosphate Catabolic Process
Nucleoside Diphosphate Catabolic Process
Cadherin Binding
Pyruvate Metabolic Process
Nucleotide Catabolic Process
Carbohydrate Catabolic Process
Shelterin Complex
Organophosphate Catabolic Process
Glucose Metabolic Process
RNA-templated DNA Biosynthetic Process
Nuclear Telomere Cap Complex
Glucose Catabolic Process
Nucleobase-containing Compound Catabolic Process
Protein Localization To Chromosome, Telomeric Region
ATP Metabolic Process
Hexose Metabolic Process
Negative Regulation Of Telomeric D-loop Disassembly
Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication
Telomere Capping
Nicotinamide Nucleotide Metabolic Process
Purine-containing Compound Metabolic Process
Generation Of Precursor Metabolites And Energy
Ficolin-1-rich Granule Lumen
Nucleobase-containing Small Molecule Metabolic Process
Monosaccharide Metabolic Process
Carbohydrate Derivative Catabolic Process
Phosphoglucomutase Activity
Nucleoside Metabolic Process
Protein Binding
Purine Ribonucleotide Metabolic Process
Calcium-dependent Phospholipid Binding
Cellular Response To Heat
Canonical Glycolysis
Negative Regulation Of Apoptotic Process
Negative Regulation Of Telomere Maintenance Via Telomerase
Ribonucleotide Metabolic Process
Glycolytic Process Through Glucose-6-phosphate
Glycolytic Process Through Fructose-6-phosphate
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