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TINF2 and CKB
Number of citations of the paper that reports this interaction (PMID
21044950
)
9
Data Source:
BioGRID
(two hybrid)
TINF2
CKB
Gene Name
TERF1 (TRF1)-interacting nuclear factor 2
creatine kinase, brain
Image
Gene Ontology Annotations
Cellular Component
Chromosome, Telomeric Region
Nuclear Telomere Cap Complex
Nucleus
Nucleoplasm
Perinucleolar Chromocenter
Nuclear Matrix
Mitochondrion
Cytosol
Extracellular Vesicular Exosome
Molecular Function
DNA Binding
Protein Binding
Telomeric DNA Binding
Creatine Kinase Activity
Protein Binding
ATP Binding
Biological Process
Telomere Maintenance
Telomere Maintenance Via Telomere Lengthening
Negative Regulation Of Protein ADP-ribosylation
Telomere Assembly
Positive Regulation Of Telomere Maintenance
Negative Regulation Of Telomere Maintenance Via Telomerase
Protein Localization To Chromosome
Negative Regulation Of Epithelial Cell Proliferation
Protein Localization To Chromosome, Telomeric Region
Creatine Metabolic Process
Phosphorylation
Substantia Nigra Development
Cellular Chloride Ion Homeostasis
Cellular Nitrogen Compound Metabolic Process
Small Molecule Metabolic Process
Pathways
Telomere Maintenance
Packaging Of Telomere Ends
DNA Damage/Telomere Stress Induced Senescence
Chromosome Maintenance
Cellular Senescence
Meiotic synapsis
Metabolism of amino acids and derivatives
Creatine metabolism
Drugs
Creatine
Diseases
GWAS
Protein-Protein Interactions
88 interactors:
ACD
ACOT7
ACTB
ADA
AFAP1L2
AIPL1
AK1
ANKMY2
ANXA4
ANXA5
APOBEC3F
APPL2
ARHGDIA
ARID3B
BAG3
BIN2
CALD1
CCDC43
CCDC9
CKB
CLK3
CPNE3
CRYGS
CTTN
DBN1
DCX
DHFRL1
DPP3
EEF1D
EIF4B
ENO2
FAM131B
FERMT3
FKBP6
GAPDH
GNMT
HNMT
HOXA3
HSP90AB1
IPO5
KCTD17
LASP1
LDHA
LGALSL
LTA4H
MAP2K3
NCDN
NOL3
NUDC
NUDCD2
OR2H1
PAGE2
PAK1IP1
PEX5
PFKP
PGM1
PGM2
PHPT1
PKM
POT1
PPP1R2
PPP6R3
PRKCB
REM2
RGS14
RPSA
SARS
SCRN2
SIAH2
STUB1
SULT1C2
TAGLN
TBL1X
TERF1
TERF2
TOMM34
TPP1
TRIM15
TRIM16
TRIP10
TUBB
TUBB4B
TXNDC17
UCHL1
VIPR1
YWHAG
ZFP36L1
ZNF790
12 interactors:
ACD
ASB9
CKM
ILK
MLH1
POT1
PPP1CA
SERP2
TAB1
TERF1
TINF2
TRIM63
Entrez ID
26277
1152
HPRD ID
16056
00423
Ensembl ID
ENSG00000092330
ENSG00000166165
Uniprot IDs
B4DFJ1
Q9BSI4
P12277
PDB IDs
3BQO
3BU8
3B6R
3DRB
3DRE
Enriched GO Terms of Interacting Partners
?
Negative Regulation Of Telomere Maintenance
Telomere Capping
Negative Regulation Of Telomere Maintenance Via Telomerase
Regulation Of Telomere Maintenance
Regulation Of Telomere Maintenance Via Telomerase
Regulation Of Telomerase Activity
Glycolytic Process
Protection From Non-homologous End Joining At Telomere
Carbohydrate Catabolic Process
Negative Regulation Of DNA Replication
Telomere Assembly
Catabolic Process
Negative Regulation Of DNA Metabolic Process
Protein Localization To Chromosome, Telomeric Region
Negative Regulation Of Catalytic Activity
Positive Regulation Of Telomerase Activity
Pyruvate Metabolic Process
Telomere Maintenance
Telomere Maintenance Via Telomerase
Pathogenesis
Generation Of Precursor Metabolites And Energy
Glucose Metabolic Process
Positive Regulation Of Single-stranded Telomeric DNA Binding
Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication
Negative Regulation Of Chromosome Organization
Small Molecule Metabolic Process
Organic Acid Metabolic Process
Regulation Of DNA Biosynthetic Process
Regulation Of Catalytic Activity
Carboxylic Acid Metabolic Process
Age-dependent Telomere Shortening
Telomeric Loop Formation
Nervous System Development
Regulation Of Signaling
Positive Regulation Of DNA Biosynthetic Process
Glycogen Metabolic Process
RNA-dependent DNA Replication
Nucleoside Metabolic Process
Telomere Maintenance Via Telomere Shortening
Regulation Of Signal Transduction
Hexose Metabolic Process
Cellular Process
Regulation Of DNA Replication
Monocarboxylic Acid Metabolic Process
Cellular Carbohydrate Metabolic Process
Response To Stimulus
Protein Localization To Chromosome
Organelle Organization
Telomere Maintenance Via Telomere Lengthening
Polysaccharide Metabolic Process
Negative Regulation Of Telomere Maintenance Via Telomerase
Negative Regulation Of Telomere Maintenance
Regulation Of Telomere Maintenance Via Telomerase
Regulation Of Telomere Maintenance
Negative Regulation Of DNA Metabolic Process
Telomere Assembly
Negative Regulation Of DNA Replication
Telomere Maintenance
Regulation Of Telomerase Activity
Negative Regulation Of Chromosome Organization
Regulation Of DNA Replication
Telomere Maintenance Via Telomere Lengthening
Regulation Of DNA Biosynthetic Process
Regulation Of Chromosome Organization
Protein Localization To Chromosome, Telomeric Region
Telomere Capping
Positive Regulation Of Telomerase Activity
Telomere Maintenance Via Telomerase
Negative Regulation Of Telomerase Activity
Positive Regulation Of Telomere Maintenance
Positive Regulation Of DNA Biosynthetic Process
Positive Regulation Of DNA Metabolic Process
Regulation Of Organelle Organization
RNA-dependent DNA Replication
Negative Regulation Of DNA Biosynthetic Process
Chromosome Organization
Protein Localization To Chromosome
DNA Metabolic Process
Positive Regulation Of Transferase Activity
Cellular Component Assembly
Negative Regulation Of Cellular Metabolic Process
Regulation Of Metabolic Process
Negative Regulation Of Transferase Activity
Positive Regulation Of DNA Replication
Negative Regulation Of Protein ADP-ribosylation
Meiotic Metaphase I Plate Congression
Positive Regulation Of Single-stranded Telomeric DNA Binding
Positive Regulation Of DNA Strand Elongation
Meiotic Spindle Midzone Assembly
Phosphocreatine Biosynthetic Process
Cell Aging
Cellular Metabolic Process
Positive Regulation Of Organelle Organization
Regulation Of Protein ADP-ribosylation
Negative Regulation Of Mitotic Recombination
Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication
Telomere Formation Via Telomerase
Telomeric Loop Formation
Age-dependent Telomere Shortening
Regulation Of Cellular Component Organization
Tagcloud
?
acd
add
broader
clustered
clustering
convincingly
correction
cosegregated
ends
families
fisher
germline
inactivating
lod
logarithm
melanoma
nonsense
pot1
predispose
probands
q320x
r364x
shelterin
tailed
terf1
terf2
terf2ip
yates
Tagcloud (Difference)
?
acd
add
broader
clustered
clustering
convincingly
correction
cosegregated
ends
families
fisher
germline
inactivating
lod
logarithm
melanoma
nonsense
pot1
predispose
probands
q320x
r364x
shelterin
tailed
terf1
terf2
terf2ip
yates
Tagcloud (Intersection)
?