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TINF2 and PEX5
Number of citations of the paper that reports this interaction (PubMedID
21044950
)
82
Data Source:
BioGRID
(two hybrid)
TINF2
PEX5
Description
TERF1 interacting nuclear factor 2
peroxisomal biogenesis factor 5
Image
GO Annotations
Cellular Component
Chromosome, Telomeric Region
Nuclear Telomere Cap Complex
Nucleus
Nucleoplasm
Chromosome
Perinucleolar Chromocenter
Nuclear Matrix
Nuclear Body
Shelterin Complex
Cytoplasm
Mitochondrion
Peroxisome
Peroxisomal Membrane
Peroxisomal Matrix
Golgi Apparatus
Cytosol
Membrane
Protein-containing Complex
Molecular Function
DNA Binding
Protein Binding
Telomeric DNA Binding
Peroxisome Targeting Sequence Binding
Peroxisome Matrix Targeting Signal-1 Binding
Protein Binding
Enzyme Binding
Small GTPase Binding
Peroxisome Membrane Targeting Sequence Binding
Protein Carrier Chaperone
Biological Process
Telomere Capping
Telomere Assembly
Positive Regulation Of Telomere Maintenance
Negative Regulation Of Telomere Maintenance Via Telomerase
Negative Regulation Of Epithelial Cell Proliferation
Protein Localization To Chromosome, Telomeric Region
Regulation Of Telomere Maintenance Via Telomere Lengthening
Very Long-chain Fatty Acid Metabolic Process
Pexophagy
Neuron Migration
Protein Monoubiquitination
Protein Targeting To Peroxisome
Lipid Metabolic Process
Fatty Acid Beta-oxidation
Mitochondrion Organization
Mitochondrial Membrane Organization
Endoplasmic Reticulum Organization
Peroxisome Organization
Protein Transport
Protein Import Into Peroxisome Matrix
Protein Import Into Peroxisome Matrix, Docking
Protein Import Into Peroxisome Matrix, Translocation
Protein Import Into Peroxisome Matrix, Receptor Recycling
Cerebral Cortex Cell Migration
Cerebral Cortex Neuron Differentiation
Negative Regulation Of Protein-containing Complex Assembly
Cellular Response To Reactive Oxygen Species
Positive Regulation Of Multicellular Organism Growth
Protein Unfolding
Protein Import Into Peroxisome Matrix, Substrate Release
Protein Import Into Peroxisome Membrane
Cell Development
Neuromuscular Process
Protein Tetramerization
Pathways
Recognition and association of DNA glycosylase with site containing an affected pyrimidine
Cleavage of the damaged pyrimidine
Recognition and association of DNA glycosylase with site containing an affected purine
Recognition and association of DNA glycosylase with site containing an affected purine
Cleavage of the damaged purine
Cleavage of the damaged purine
Meiotic synapsis
Packaging Of Telomere Ends
Telomere Extension By Telomerase
Polymerase switching on the C-strand of the telomere
Processive synthesis on the C-strand of the telomere
Telomere C-strand (Lagging Strand) Synthesis
Telomere C-strand synthesis initiation
Removal of the Flap Intermediate from the C-strand
DNA Damage/Telomere Stress Induced Senescence
Inhibition of DNA recombination at telomere
Pexophagy
Drugs
Diseases
Revesz syndrome; Exudative retinopathy with bone marrow failure
Zellweger syndrome spectrum, including: Zellweger syndrome (ZS); Adrenoleukodystrophy, neonatal (NALD); Infantile Refsum disease (IRD)
GWAS
Leukocyte telomere length (
31171785
)
Platelet count (
29403010
)
IgG glycosylation (
23382691
)
Night sleep phenotypes (
27126917
)
Refractive error (
32231278
)
Interacting Genes
91 interacting genes:
ACD
ACOT7
ACTB
ADA
AFAP1L2
AIPL1
AK1
ANKMY2
ANXA4
ANXA5
ANXA8L1
APOBEC3F
APPL2
ARHGDIA
ARID3B
BAG3
BIN2
CALD1
CCDC43
CCDC9
CKB
CLK3
CPNE3
CRYGS
CSNK2A1
CTTN
DBN1
DCX
DHFR2
DPP3
EEF1D
EIF4B
ENO2
FAM131B
FERMT3
FKBP6
GAPDH
GNMT
HNMT
HOXA3
HSP90AB1
IPO5
KCTD17
LASP1
LDHA
LGALSL
LTA4H
MAP2K3
MTNR1B
NCDN
NOL3
NUDC
NUDCD2
OR2H1
PAGE2
PAK1IP1
PEX5
PFKP
PGM1
PGM2
PHPT1
PKM
PPP1R2
PPP6R3
PRKCB
REM2
RGS14
RPSA
SARS1
SCRN2
SIAH2
STUB1
SULT1C2
TAGLN
TBL1X
TERF1
TERF2
TFRC
TOMM34
TPP1
TRIM15
TRIM16
TRIP10
TUBB
TUBB4B
TXNDC17
UCHL1
VIPR1
YWHAG
ZFP36L1
ZNF790
77 interacting genes:
ACD
ACOT2
ACOT4
ACOT8
ACOX2
ACOX3
AGXT
AMACR
ANKRD50
ATM
BAAT
BRCA1
CAPRIN2
CCDC14
CROT
DAO
DDO
DECR2
DHRS4
ECI2
EP400P1
EPHX2
GDPD5
GLMN
GNPAT
GSTK1
HACL1
HAO1
HAO2
HMGCL
HNRNPH1
HOXA7
HSPA1A
IDE
IDH1
LDHB
LONP2
MKRN3
MLYCD
MPV17
NOS2
NUDT19
NUDT3
NUDT7
NUFIP2
PAOX
PDZK1
PEX1
PEX10
PEX12
PEX13
PEX14
PEX26
PEX6
PEX7
PIPOX
POT1
PRDX5
PRR13
PSAP
RPL14
S100A6
SCARB1
SCP2
SCRN2
SIRT3
SLC27A2
SNUPN
SSTR5
TIMMDC1
TINF2
TM6SF1
TOMM7
USP2
USP9X
ZFAND3
ZNF772
Entrez ID
26277
5830
HPRD ID
16056
02684
Ensembl ID
ENSG00000092330
ENSG00000139197
Uniprot IDs
B4DFJ1
Q9BSI4
A0A0S2Z480
A0A0S2Z4F3
A0A0S2Z4H1
B4DR50
B4E0T2
P50542
PDB IDs
3BQO
3BU8
5XYF
1FCH
2C0L
2C0M
2J9Q
2W84
3R9A
4BXU
4KXK
4KYO
7Z0K
9GAG
Enriched GO Terms of Interacting Partners
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Cytosol
Extracellular Exosome
Cytoplasm
ADP Metabolic Process
Purine Ribonucleotide Catabolic Process
Ribonucleoside Diphosphate Metabolic Process
Glycolytic Process
ADP Catabolic Process
Purine Nucleotide Catabolic Process
Nucleoside Phosphate Catabolic Process
Nucleoside Diphosphate Metabolic Process
Purine Ribonucleoside Diphosphate Catabolic Process
Ribonucleoside Diphosphate Catabolic Process
Nucleoside Diphosphate Catabolic Process
Cadherin Binding
Pyruvate Metabolic Process
Nucleotide Catabolic Process
Carbohydrate Catabolic Process
Shelterin Complex
Organophosphate Catabolic Process
Glucose Metabolic Process
RNA-templated DNA Biosynthetic Process
Nuclear Telomere Cap Complex
Glucose Catabolic Process
Nucleobase-containing Compound Catabolic Process
Protein Localization To Chromosome, Telomeric Region
ATP Metabolic Process
Hexose Metabolic Process
Negative Regulation Of Telomeric D-loop Disassembly
Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication
Telomere Capping
Nicotinamide Nucleotide Metabolic Process
Purine-containing Compound Metabolic Process
Generation Of Precursor Metabolites And Energy
Ficolin-1-rich Granule Lumen
Nucleobase-containing Small Molecule Metabolic Process
Monosaccharide Metabolic Process
Carbohydrate Derivative Catabolic Process
Phosphoglucomutase Activity
Nucleoside Metabolic Process
Protein Binding
Purine Ribonucleotide Metabolic Process
Calcium-dependent Phospholipid Binding
Cellular Response To Heat
Canonical Glycolysis
Negative Regulation Of Apoptotic Process
Negative Regulation Of Telomere Maintenance Via Telomerase
Ribonucleotide Metabolic Process
Glycolytic Process Through Glucose-6-phosphate
Glycolytic Process Through Fructose-6-phosphate
Peroxisome
Peroxisomal Matrix
Carboxylic Acid Catabolic Process
Establishment Of Protein Localization To Peroxisome
Protein Import Into Peroxisome Matrix
Fatty Acid Oxidation
Carboxylic Acid Metabolic Process
Fatty Acid Catabolic Process
Organic Acid Metabolic Process
Lipid Oxidation
Peroxisome Organization
Fatty Acid Metabolic Process
Monocarboxylic Acid Metabolic Process
Peroxisomal Membrane Transport
Peroxisomal Membrane
Lipid Modification
Protein Import Into Peroxisome Matrix, Receptor Recycling
Intracellular Protein Transmembrane Transport
Fatty Acid Beta-oxidation Using Acyl-CoA Oxidase
Small Molecule Metabolic Process
Lipid Metabolic Process
Protein Unfolding
Lipid Catabolic Process
Protein Transmembrane Transport
Catabolic Process
Fatty Acid Beta-oxidation
Receptor Recycling
Protein Targeting To Peroxisome
Cytosol
Establishment Of Protein Localization To Organelle
Receptor Metabolic Process
Sulfur Compound Metabolic Process
Acyl-CoA Metabolic Process
Bile Acid Biosynthetic Process
Carboxylic Acid Biosynthetic Process
Protein Import Into Peroxisome Matrix, Substrate Release
Bile Acid Metabolic Process
Fatty Acid Alpha-oxidation
Oxidoreductase Activity
Protein Localization To Organelle
Purine-containing Compound Metabolic Process
Small Molecule Biosynthetic Process
Peroxisomal Importomer Complex
Malonyl-CoA Catabolic Process
Protein Transmembrane Transporter Activity
Nucleoside Phosphate Metabolic Process
Nucleobase-containing Small Molecule Metabolic Process
Protein Import Into Peroxisome Matrix, Translocation
Telomere Assembly
Organophosphate Metabolic Process
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Tagcloud (Intersection)
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