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TINF2 and NUDCD2
Number of citations of the paper that reports this interaction (PubMedID
21044950
)
82
Data Source:
BioGRID
(two hybrid)
TINF2
NUDCD2
Description
TERF1 interacting nuclear factor 2
NudC domain containing 2
Image
No pdb structure
GO Annotations
Cellular Component
Chromosome, Telomeric Region
Nuclear Telomere Cap Complex
Nucleus
Nucleoplasm
Chromosome
Perinucleolar Chromocenter
Nuclear Matrix
Nuclear Body
Shelterin Complex
Chromosome, Centromeric Region
Kinetochore
Spindle Pole
Chromosome
Cytoplasm
Centrosome
Cytosol
Cytoskeleton
Microtubule Cytoskeleton
Intercellular Bridge
Mitotic Spindle
Molecular Function
DNA Binding
Protein Binding
Telomeric DNA Binding
Protein Binding
Unfolded Protein Binding
Biological Process
Telomere Capping
Telomere Assembly
Positive Regulation Of Telomere Maintenance
Negative Regulation Of Telomere Maintenance Via Telomerase
Negative Regulation Of Epithelial Cell Proliferation
Protein Localization To Chromosome, Telomeric Region
Regulation Of Telomere Maintenance Via Telomere Lengthening
Protein Folding
Pathways
Recognition and association of DNA glycosylase with site containing an affected pyrimidine
Cleavage of the damaged pyrimidine
Recognition and association of DNA glycosylase with site containing an affected purine
Recognition and association of DNA glycosylase with site containing an affected purine
Cleavage of the damaged purine
Cleavage of the damaged purine
Meiotic synapsis
Packaging Of Telomere Ends
Telomere Extension By Telomerase
Polymerase switching on the C-strand of the telomere
Processive synthesis on the C-strand of the telomere
Telomere C-strand (Lagging Strand) Synthesis
Telomere C-strand synthesis initiation
Removal of the Flap Intermediate from the C-strand
DNA Damage/Telomere Stress Induced Senescence
Inhibition of DNA recombination at telomere
Drugs
Diseases
Revesz syndrome; Exudative retinopathy with bone marrow failure
GWAS
Leukocyte telomere length (
31171785
)
Platelet count (
29403010
)
Interacting Genes
91 interacting genes:
ACD
ACOT7
ACTB
ADA
AFAP1L2
AIPL1
AK1
ANKMY2
ANXA4
ANXA5
ANXA8L1
APOBEC3F
APPL2
ARHGDIA
ARID3B
BAG3
BIN2
CALD1
CCDC43
CCDC9
CKB
CLK3
CPNE3
CRYGS
CSNK2A1
CTTN
DBN1
DCX
DHFR2
DPP3
EEF1D
EIF4B
ENO2
FAM131B
FERMT3
FKBP6
GAPDH
GNMT
HNMT
HOXA3
HSP90AB1
IPO5
KCTD17
LASP1
LDHA
LGALSL
LTA4H
MAP2K3
MTNR1B
NCDN
NOL3
NUDC
NUDCD2
OR2H1
PAGE2
PAK1IP1
PEX5
PFKP
PGM1
PGM2
PHPT1
PKM
PPP1R2
PPP6R3
PRKCB
REM2
RGS14
RPSA
SARS1
SCRN2
SIAH2
STUB1
SULT1C2
TAGLN
TBL1X
TERF1
TERF2
TFRC
TOMM34
TPP1
TRIM15
TRIM16
TRIP10
TUBB
TUBB4B
TXNDC17
UCHL1
VIPR1
YWHAG
ZFP36L1
ZNF790
5 interacting genes:
ACD
MYH9
POT1
TERF1
TINF2
Entrez ID
26277
134492
HPRD ID
16056
14058
Ensembl ID
ENSG00000092330
ENSG00000170584
Uniprot IDs
B4DFJ1
Q9BSI4
Q8WVJ2
PDB IDs
3BQO
3BU8
5XYF
Enriched GO Terms of Interacting Partners
?
Cytosol
Extracellular Exosome
Cytoplasm
ADP Metabolic Process
Purine Ribonucleotide Catabolic Process
Ribonucleoside Diphosphate Metabolic Process
Glycolytic Process
ADP Catabolic Process
Purine Nucleotide Catabolic Process
Nucleoside Phosphate Catabolic Process
Nucleoside Diphosphate Metabolic Process
Purine Ribonucleoside Diphosphate Catabolic Process
Ribonucleoside Diphosphate Catabolic Process
Nucleoside Diphosphate Catabolic Process
Cadherin Binding
Pyruvate Metabolic Process
Nucleotide Catabolic Process
Carbohydrate Catabolic Process
Shelterin Complex
Organophosphate Catabolic Process
Glucose Metabolic Process
RNA-templated DNA Biosynthetic Process
Nuclear Telomere Cap Complex
Glucose Catabolic Process
Nucleobase-containing Compound Catabolic Process
Protein Localization To Chromosome, Telomeric Region
ATP Metabolic Process
Hexose Metabolic Process
Negative Regulation Of Telomeric D-loop Disassembly
Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication
Telomere Capping
Nicotinamide Nucleotide Metabolic Process
Purine-containing Compound Metabolic Process
Generation Of Precursor Metabolites And Energy
Ficolin-1-rich Granule Lumen
Nucleobase-containing Small Molecule Metabolic Process
Monosaccharide Metabolic Process
Carbohydrate Derivative Catabolic Process
Phosphoglucomutase Activity
Nucleoside Metabolic Process
Protein Binding
Purine Ribonucleotide Metabolic Process
Calcium-dependent Phospholipid Binding
Cellular Response To Heat
Canonical Glycolysis
Negative Regulation Of Apoptotic Process
Negative Regulation Of Telomere Maintenance Via Telomerase
Ribonucleotide Metabolic Process
Glycolytic Process Through Glucose-6-phosphate
Glycolytic Process Through Fructose-6-phosphate
Shelterin Complex
Nuclear Telomere Cap Complex
Telomere Capping
Negative Regulation Of Telomere Maintenance Via Telomerase
Telomeric DNA Binding
Negative Regulation Of DNA Biosynthetic Process
Negative Regulation Of Telomere Maintenance Via Telomere Lengthening
Telomere Assembly
Negative Regulation Of Telomere Maintenance
Regulation Of Telomere Maintenance Via Telomerase
Regulation Of Telomere Maintenance Via Telomere Lengthening
Positive Regulation Of Telomere Maintenance
Negative Regulation Of Chromosome Organization
Regulation Of DNA Biosynthetic Process
Telomere Maintenance
Positive Regulation Of Chromosome Organization
Regulation Of Telomere Maintenance
Telomere Organization
Negative Regulation Of DNA Metabolic Process
Telomere Maintenance Via Telomerase
RNA-templated DNA Biosynthetic Process
Telomere Maintenance Via Telomere Lengthening
Chromosome, Telomeric Region
Regulation Of Chromosome Organization
Positive Regulation Of DNA Metabolic Process
Chromosome Organization
Nuclear Body
Regulation Of Establishment Of Protein Localization To Telomere
Regulation Of Establishment Of Protein Localization To Chromosome
DNA Biosynthetic Process
Telomerase Inhibitor Activity
Establishment Of Protein Localization To Telomere
Telomeric D-loop Disassembly
G-rich Strand Telomeric DNA Binding
Regulation Of DNA Metabolic Process
Telomeric Loop Disassembly
Positive Regulation Of Organelle Organization
Protein Localization To Chromosome, Telomeric Region
Chromosome
Negative Regulation Of Cellular Component Organization
DNA Metabolic Process
Regulation Of Cellular Component Organization
Organelle Organization
Positive Regulation Of Cellular Component Organization
Regulation Of Organelle Organization
Positive Regulation Of Macromolecule Metabolic Process
Cortical Granule Exocytosis
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Negative Regulation Of Establishment Of Protein Localization To Telomere
Negative Regulation Of Establishment Of Protein-containing Complex Localization To Telomere
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