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TINF2 and FERMT3
Number of citations of the paper that reports this interaction (PubMedID
21044950
)
82
Data Source:
BioGRID
(two hybrid)
TINF2
FERMT3
Description
TERF1 interacting nuclear factor 2
FERM domain containing kindlin 3
Image
GO Annotations
Cellular Component
Chromosome, Telomeric Region
Nuclear Telomere Cap Complex
Nucleus
Nucleoplasm
Chromosome
Perinucleolar Chromocenter
Nuclear Matrix
Nuclear Body
Shelterin Complex
Podosome
Extracellular Region
Membrane
Cell-substrate Junction
Platelet Alpha Granule Lumen
Cell Projection
Extracellular Exosome
Anchoring Junction
Molecular Function
DNA Binding
Protein Binding
Telomeric DNA Binding
Integrin Binding
Protein Binding
Lipid Binding
Biological Process
Telomere Capping
Telomere Assembly
Positive Regulation Of Telomere Maintenance
Negative Regulation Of Telomere Maintenance Via Telomerase
Negative Regulation Of Epithelial Cell Proliferation
Protein Localization To Chromosome, Telomeric Region
Regulation Of Telomere Maintenance Via Telomere Lengthening
Cell Adhesion
Leukocyte Cell-cell Adhesion
Cell-matrix Adhesion
Integrin-mediated Signaling Pathway
Positive Regulation Of Cell Migration
Integrin Activation
Regulation Of Cell-cell Adhesion Mediated By Integrin
Substrate Adhesion-dependent Cell Spreading
Platelet Aggregation
Pathways
Recognition and association of DNA glycosylase with site containing an affected pyrimidine
Cleavage of the damaged pyrimidine
Recognition and association of DNA glycosylase with site containing an affected purine
Recognition and association of DNA glycosylase with site containing an affected purine
Cleavage of the damaged purine
Cleavage of the damaged purine
Meiotic synapsis
Packaging Of Telomere Ends
Telomere Extension By Telomerase
Polymerase switching on the C-strand of the telomere
Processive synthesis on the C-strand of the telomere
Telomere C-strand (Lagging Strand) Synthesis
Telomere C-strand synthesis initiation
Removal of the Flap Intermediate from the C-strand
DNA Damage/Telomere Stress Induced Senescence
Inhibition of DNA recombination at telomere
Platelet degranulation
Drugs
Diseases
Revesz syndrome; Exudative retinopathy with bone marrow failure
Leukocyte adhesion deficiency (LAD), including the following four diseases: Leukocyte adhesion deficiency (I); Leukocyte adhesion deficiency (II); Leukocyte adhesion deficiency (III); LAD with Rac2 deficiency
GWAS
Leukocyte telomere length (
31171785
)
Platelet count (
29403010
)
Attention deficit hyperactivity disorder (
21784300
)
Crohn's disease (
28067908
)
Fruit consumption (
32066663
)
High light scatter reticulocyte count (
27863252
32888494
)
High light scatter reticulocyte percentage of red cells (
27863252
32888494
)
Immature fraction of reticulocytes (
27863252
32888494
)
Mean platelet volume (
32888494
)
Medication use (agents acting on the renin-angiotensin system) (
31015401
)
Medication use (HMG CoA reductase inhibitors) (
31015401
)
Interacting Genes
91 interacting genes:
ACD
ACOT7
ACTB
ADA
AFAP1L2
AIPL1
AK1
ANKMY2
ANXA4
ANXA5
ANXA8L1
APOBEC3F
APPL2
ARHGDIA
ARID3B
BAG3
BIN2
CALD1
CCDC43
CCDC9
CKB
CLK3
CPNE3
CRYGS
CSNK2A1
CTTN
DBN1
DCX
DHFR2
DPP3
EEF1D
EIF4B
ENO2
FAM131B
FERMT3
FKBP6
GAPDH
GNMT
HNMT
HOXA3
HSP90AB1
IPO5
KCTD17
LASP1
LDHA
LGALSL
LTA4H
MAP2K3
MTNR1B
NCDN
NOL3
NUDC
NUDCD2
OR2H1
PAGE2
PAK1IP1
PEX5
PFKP
PGM1
PGM2
PHPT1
PKM
PPP1R2
PPP6R3
PRKCB
REM2
RGS14
RPSA
SARS1
SCRN2
SIAH2
STUB1
SULT1C2
TAGLN
TBL1X
TERF1
TERF2
TFRC
TOMM34
TPP1
TRIM15
TRIM16
TRIP10
TUBB
TUBB4B
TXNDC17
UCHL1
VIPR1
YWHAG
ZFP36L1
ZNF790
11 interacting genes:
ANKRD29
APP
EXOSC10
ILK
ITGB1
LIMS1
LSM8
PARVA
PRPF18
TINF2
TRIM15
Entrez ID
26277
83706
HPRD ID
16056
07440
Ensembl ID
ENSG00000092330
ENSG00000149781
Uniprot IDs
B4DFJ1
Q9BSI4
F5H3I6
Q86UX7
PDB IDs
3BQO
3BU8
5XYF
2YS3
6V97
6V9G
7C3M
Enriched GO Terms of Interacting Partners
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Cytosol
Extracellular Exosome
Cytoplasm
ADP Metabolic Process
Purine Ribonucleotide Catabolic Process
Ribonucleoside Diphosphate Metabolic Process
Glycolytic Process
ADP Catabolic Process
Purine Nucleotide Catabolic Process
Nucleoside Phosphate Catabolic Process
Nucleoside Diphosphate Metabolic Process
Purine Ribonucleoside Diphosphate Catabolic Process
Ribonucleoside Diphosphate Catabolic Process
Nucleoside Diphosphate Catabolic Process
Cadherin Binding
Pyruvate Metabolic Process
Nucleotide Catabolic Process
Carbohydrate Catabolic Process
Shelterin Complex
Organophosphate Catabolic Process
Glucose Metabolic Process
RNA-templated DNA Biosynthetic Process
Nuclear Telomere Cap Complex
Glucose Catabolic Process
Nucleobase-containing Compound Catabolic Process
Protein Localization To Chromosome, Telomeric Region
ATP Metabolic Process
Hexose Metabolic Process
Negative Regulation Of Telomeric D-loop Disassembly
Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication
Telomere Capping
Nicotinamide Nucleotide Metabolic Process
Purine-containing Compound Metabolic Process
Generation Of Precursor Metabolites And Energy
Ficolin-1-rich Granule Lumen
Nucleobase-containing Small Molecule Metabolic Process
Monosaccharide Metabolic Process
Carbohydrate Derivative Catabolic Process
Phosphoglucomutase Activity
Nucleoside Metabolic Process
Protein Binding
Purine Ribonucleotide Metabolic Process
Calcium-dependent Phospholipid Binding
Cellular Response To Heat
Canonical Glycolysis
Negative Regulation Of Apoptotic Process
Negative Regulation Of Telomere Maintenance Via Telomerase
Ribonucleotide Metabolic Process
Glycolytic Process Through Glucose-6-phosphate
Glycolytic Process Through Fructose-6-phosphate
Anchoring Junction
Focal Adhesion
Regulation Of Spontaneous Synaptic Transmission
Integrin Binding
Cell Adhesion
Regulation Of Neurotransmitter Uptake
Cell-substrate Adhesion
Negative Regulation Of Telomere Maintenance Via Telomerase
Negative Regulation Of DNA Biosynthetic Process
Negative Regulation Of Telomere Maintenance Via Telomere Lengthening
Cell-cell Adhesion
Heterotypic Cell-cell Adhesion
Amyloid-beta Complex
Growth Cone Lamellipodium
Regulation Of Response To Calcium Ion
Amylin Binding
Positive Regulation Of Toll Signaling Pathway
Visual Learning
Positive Regulation Of Intracellular Signal Transduction
Regulation Of Substrate Adhesion-dependent Cell Spreading
Tumor Necrosis Factor-mediated Signaling Pathway
Positive Regulation Of Substrate Adhesion-dependent Cell Spreading
Substrate Adhesion-dependent Cell Spreading
Myoblast Fate Specification
Integrin Alpha7-beta1 Complex
Regulation Of Telomere Maintenance Via Telomerase
Regulation Of Telomere Maintenance Via Telomere Lengthening
Negative Regulation Of Telomere Maintenance
Nuclear Polyadenylation-dependent Antisense Transcript Catabolic Process
U4/U6 X U5 Tri-snRNP Complex
U2-type Post-spliceosomal Complex
Visual Behavior
Glial Cell Development
Synaptic Membrane
Acetylcholine Receptor Activator Activity
Lipoprotein Particle
Positive Regulation Of Protein Import
Integrin Alpha6-beta1 Complex
Positive Regulation Of Glutamate Uptake Involved In Transmission Of Nerve Impulse
Integrin Alpha8-beta1 Complex
Integrin Alpha1-beta1 Complex
Integrin Alpha5-beta1 Complex
Integrin Alpha10-beta1 Complex
Integrin Alphav-beta1 Complex
Integrin Alpha11-beta1 Complex
Cardiac Cell Fate Specification
Integrin Alpha3-beta1 Complex
Integrin Alpha9-beta1 Complex
Nuclear Polyadenylation-dependent SnoRNA Catabolic Process
Nuclear Polyadenylation-dependent SnRNA Catabolic Process
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Tagcloud (Difference)
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Tagcloud (Intersection)
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