ANXA5 and COL10A1

Number of citations of the paper that reports this interaction (PubMedID 1397263)
0

Data Source:
BioGRID (pull down)
HPRD (in vitro)

		ANXA5	COL10A1
Description		annexin A5	collagen type X alpha 1 chain
Image
GO Annotations	Cellular Component	Extracellular Region Cytoplasm Cytosol Focal Adhesion External Side Of Plasma Membrane Vesicle Membrane Membrane Extracellular Matrix Sarcolemma Extracellular Exosome Endothelial Microparticle	Extracellular Region Collagen Trimer Collagen Type X Trimer Endoplasmic Reticulum Lumen Extracellular Matrix
	Molecular Function	Phosphatidylserine Binding Phospholipase Inhibitor Activity Calcium Ion Binding Protein Binding Phospholipid Binding Calcium-dependent Phospholipid Binding	Protein Binding Extracellular Matrix Structural Constituent Conferring Tensile Strength Metal Ion Binding
	Biological Process	Signal Transduction Blood Coagulation Hemostasis Negative Regulation Of Apoptotic Process Negative Regulation Of Coagulation	Skeletal System Development
Pathways		Platelet degranulation	Collagen degradation Collagen degradation Collagen biosynthesis and modifying enzymes Assembly of collagen fibrils and other multimeric structures Integrin cell surface interactions Non-integrin membrane-ECM interactions Collagen chain trimerization
Drugs		Fluocinolone acetonide L-Alpha-Glycerophosphorylserine L-thioproline K201 free base sn-glycero-3-phosphoethanolamine 1,4-Dideoxy-O2-Sulfo-Glucuronic Acid N,O6-Disulfo-Glucosamine 1,4-Dideoxy-5-Dehydro-O2-Sulfo-Glucuronic Acid Copper
Diseases			Metaphyseal dysplasias, including: Metaphyseal dysplasia, Schmid type; Metaphyseal dysplasia, McKusik type; Metaphyseal dysplasia, Jansen type; Shwachman-Bodian-Diamond syndrome (SBDS); Metaphyseal anadysplasia (MAD)
GWAS		A body shape index ( 34021172) Age at smoking initiation in chronic obstructive pulmonary disease ( 21685187) Age-related cognitive decline (language) (slope of z-scores) ( 30954325) Resting-state electroencephalogram vigilance ( 29703947) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)	Age-related macular degeneration ( 21665990 23455636) Gemcitabine-induced early high-grade neutropenia in pancreatic cancer ( 30889042) Myopia ( 27182965) Refractive error ( 32231278) Spherical equivalent or myopia (age of diagnosis) ( 29808027)
Interacting Genes		20 interacting genes: ACTG1 APP CEBPA COL10A1 COL2A1 EED EIF4G1 FDFT1 GSC2 IFNGR2 ITGB5 KDR LAMC3 LINC01554 PPP2R1B SUPT4H1 TERF1 TERF2 TERF2IP TINF2	10 interacting genes: ANXA5 BANP CIDEB MESD NRF1 P4HB SGTB UBQLN1 UBQLN2 VSNL1
Entrez ID		308	1300
HPRD ID		00568	00357
Ensembl ID		ENSG00000164111	ENSG00000123500
Uniprot IDs		P08758 V9HWE0	A0A650AXN9 Q03692
PDB IDs		1ANW 1ANX 1AVH 1AVR 1HAK 1HVD 1HVE 1HVF 1HVG 1SAV 2XO2 2XO3 6K22 6K25 8GYC 8H0J 8H9Z	1GR3
Enriched GO Terms of Interacting Partners?		Shelterin Complex Nuclear Telomere Cap Complex Telomere Capping Telomeric DNA Binding Negative Regulation Of Chromosome Organization Negative Regulation Of Telomere Maintenance Positive Regulation Of Chromosome Organization G-rich Strand Telomeric DNA Binding Protein Localization To Chromosome, Telomeric Region Negative Regulation Of Telomeric D-loop Disassembly Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Negative Regulation Of DNA Recombination At Telomere Positive Regulation Of Telomere Maintenance Negative Regulation Of Telomere Maintenance Via Telomerase RNA-templated DNA Biosynthetic Process Negative Regulation Of Telomere Maintenance Via Telomere Lengthening Telomere Maintenance Negative Regulation Of DNA Biosynthetic Process Regulation Of Telomere Maintenance Regulation Of Chromosome Organization Telomere Organization Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of DNA Metabolic Process Positive Regulation Of Organelle Organization Telomerase Activity Protection From Non-homologous End Joining At Telomere Regulation Of Telomere Maintenance Via Telomere Lengthening Positive Regulation Of Cellular Component Organization Telomeric D-loop Disassembly Double-stranded Telomeric DNA Binding Chromosome Organization Chromosome, Telomeric Region Telomeric Loop Disassembly Telomere Maintenance In Response To DNA Damage Chromosome Regulation Of DNA Biosynthetic Process DNA Biosynthetic Process Multicellular Organismal-level Homeostasis Regulation Of Cell Junction Assembly Telomere Maintenance Via Telomerase Protein Localization To Chromosome Negative Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of DNA Metabolic Process Epithelial Cell Maturation Regulation Of Organelle Organization Regulation Of Presynapse Organization Regulation Of Presynapse Assembly Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Mitotic Cell Cycle Negative Regulation Of Macromolecule Metabolic Process	Response To Endoplasmic Reticulum Stress Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Identical Protein Binding Positive Regulation Of ERAD Pathway Polyubiquitin Modification-dependent Protein Binding Positive Regulation Of Response To Endoplasmic Reticulum Stress Regulation Of ERAD Pathway Negative Regulation Of Store-operated Calcium Channel Activity Endothelial Microparticle Peptidyl-proline Hydroxylation To 4-hydroxy-L-proline Procollagen-proline 4-dioxygenase Complex Autophagosome Regulation Of Response To Endoplasmic Reticulum Stress Autophagosome Assembly ERAD Pathway Negative Regulation Of G Protein-coupled Receptor Internalization TRC Complex Negative Regulation Of Transport Autophagosome Organization Negative Regulation Of Toll-like Receptor 3 Signaling Pathway Positive Regulation Of Proteasomal Protein Catabolic Process Peptidyl-proline Hydroxylation Negative Regulation Of Clathrin-dependent Endocytosis Procollagen-proline 4-dioxygenase Activity Cellular Response To Hypoxia Lipid Droplet Fusion Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Cellular Response To Decreased Oxygen Levels
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?