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RPA4 and XPA
Number of citations of the paper that reports this interaction (PMID
7565690
)
52
Data Source:
HPRD
(two hybrid, in vitro)
RPA4
XPA
Gene Name
replication protein A4, 30kDa
xeroderma pigmentosum, complementation group A
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
DNA Replication Factor A Complex
Nucleus
Nucleoplasm
DNA Replication Factor A Complex
Cytoplasm
Golgi Apparatus
Intercellular Bridge
Molecular Function
Single-stranded DNA Binding
Damaged DNA Binding
Protein Binding
Protein Domain Specific Binding
Protein Homodimerization Activity
Metal Ion Binding
Biological Process
DNA Damage Checkpoint
G1/S Transition Of Mitotic Cell Cycle
Mitotic Cell Cycle
DNA Replication Initiation
Nucleotide-excision Repair
DNA Recombination
Nuclear DNA Replication
Nucleotide-excision Repair, DNA Damage Removal
DNA Repair
Nucleotide-excision Repair
Response To Oxidative Stress
Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage
Response To UV
Response To Toxic Substance
Multicellular Organism Growth
Pathways
G1/S Transition
Activation of the pre-replicative complex
DNA Replication Pre-Initiation
M/G1 Transition
Activation of the pre-replicative complex
Mitotic G1-G1/S phases
Cell Cycle, Mitotic
Nucleotide Excision Repair
Global Genomic NER (GG-NER)
Formation of incision complex in GG-NER
Dual incision reaction in GG-NER
Drugs
Diseases
GWAS
Obesity-related traits (
23251661
)
Thyroid cancer (Papillary, radiation-related) (
20350937
)
Protein-Protein Interactions
7 interactors:
APP
MSH2
MSH3
MUTYH
RPA1
RPA3
XPA
20 interactors:
ATM
ATR
DDB1
DDB2
ERCC1
ERCC6
GPN1
GTF2E2
GTF2H1
HERC2
MSH2
MSH3
NDEL1
PRKDC
RASSF1
RPA1
RPA2
RPA4
TRIM27
XAB2
Entrez ID
29935
7507
HPRD ID
06591
02045
Ensembl ID
ENSG00000204086
ENSG00000136936
Uniprot IDs
Q13156
P23025
PDB IDs
1D4U
1XPA
2JNW
Enriched GO Terms of Interacting Partners
?
Mismatch Repair
DNA Repair
Nucleotide-excision Repair, DNA Damage Removal
Cellular Response To DNA Damage Stimulus
DNA Catabolic Process
DNA Metabolic Process
Meiotic Mismatch Repair
DNA Recombination
Maintenance Of DNA Repeat Elements
Cellular Response To Stress
Base-excision Repair
DNA Recombinase Assembly
Positive Regulation Of Helicase Activity
Response To Stress
Nucleotide-excision Repair
Response To Abiotic Stimulus
Aromatic Compound Catabolic Process
Double-strand Break Repair
Nucleotide-excision Repair, DNA Gap Filling
Nucleobase-containing Compound Metabolic Process
Meiotic Nuclear Division
Telomere Maintenance Via Semi-conservative Replication
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Negative Regulation Of DNA Recombination
Nuclear DNA Replication
Telomere Maintenance Via Recombination
Cellular Nitrogen Compound Metabolic Process
Meiotic Cell Cycle
Mitotic Recombination
DNA Strand Elongation Involved In DNA Replication
Regulation Of Cellular Response To Heat
DNA Strand Elongation
Telomere Maintenance Via Telomere Lengthening
Nitrogen Compound Metabolic Process
Somatic Recombination Of Immunoglobulin Gene Segments
Somatic Diversification Of Immunoglobulins
Cellular Macromolecule Catabolic Process
Transcription-coupled Nucleotide-excision Repair
Response To Light Stimulus
Chromosome Organization
Reproduction
Cell Cycle Process
Cellular Response To Stimulus
Immunoglobulin Production
Cellular Response To Heat
Regulation Of DNA Recombination
Regulation Of Mitotic Cell Cycle
Telomere Maintenance
Response To Radiation
DNA Repair
Cellular Response To DNA Damage Stimulus
Nucleotide-excision Repair
DNA Metabolic Process
Cellular Response To Stress
Nucleotide-excision Repair, DNA Damage Removal
DNA Recombination
Transcription-coupled Nucleotide-excision Repair
Response To Stress
Double-strand Break Repair
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Response To UV
Cellular Aromatic Compound Metabolic Process
Response To Ionizing Radiation
Response To Radiation
DNA Catabolic Process
DNA Damage Checkpoint
Cellular Nitrogen Compound Metabolic Process
Cell Cycle Process
Response To Abiotic Stimulus
Double-strand Break Repair Via Homologous Recombination
Recombinational Repair
Nitrogen Compound Metabolic Process
Regulation Of Cellular Response To Heat
Somatic Recombination Of Immunoglobulin Gene Segments
Somatic Diversification Of Immunoglobulins
Cell Cycle Checkpoint
Cell Cycle
Chromosome Organization
Aromatic Compound Catabolic Process
Pyrimidine Dimer Repair
Response To Gamma Radiation
Mismatch Repair
Cellular Response To Stimulus
Immunoglobulin Production
Cellular Macromolecule Catabolic Process
Response To Light Stimulus
Cellular Response To Heat
Telomere Maintenance
Mitotic Cell Cycle Process
Reproduction
Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage
Mitotic DNA Damage Checkpoint
Organelle Organization
Negative Regulation Of DNA Metabolic Process
Mitotic DNA Integrity Checkpoint
Mitotic Cell Cycle
Response To X-ray
Mitotic Recombination
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Tagcloud (Difference)
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Tagcloud (Intersection)
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