BLNK and BTK

  • Number of citations of the paper that reports this interaction (PMID 10556826)
  • 52
  • Data Source:
  • HPRD (in vivo, in vitro)

BLNK

BTK

Gene Name B-cell linker Bruton agammaglobulinemia tyrosine kinase
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 20 interactors: BTK CBL CBLB CD72 CD79A CMTM3 CRKL ERBB2 GRAP2 GRB2 ITK LCP2 MAP4K1 NCK1 PLCG1 PLCG2 PTPN6 SH3KBP1 SYK VAV1 64 interactors: ABL1 APP ARHGAP17 ARID3A ARRB1 BCL2L11 BLNK BMX CAV1 CBL CD19 CMTM3 DAPP1 EWSR1 FAS FASLG FYN GNA12 GNAQ GNG2 GTF2I HCK IBTK IRAK1 ITK JAK1 KHDRBS1 KIT LYN MYD88 PIK3AP1 PIP4K2A PIP4K2B PIP4K2C PIP5K1A PIP5K1B PIP5K1C PLAU PLCG1 PLCG2 PRKCA PRKCB PRKCE PRKCQ PRKCZ PRKD1 RELA RPS6KB1 RPS6KB2 SH2B2 SH3BP5 STAT5A SYK TEC TIRAP TLR4 TLR6 TLR8 TLR9 TNFRSF10A TP53 VAV1 WAS WASF2
Entrez ID 29760 695
HPRD ID 05153 02248
Ensembl ID ENSG00000095585 ENSG00000010671
Uniprot IDs Q2MD54 Q2MD59 Q8WV28 Q06187 Q5JY90
PDB IDs 1AWW 1AWX 1B55 1BTK 1BWN 1K2P 1QLY 2GE9 2Z0P 3GEN 3K54 3OCS 3OCT 3P08 3PIX 3PIY 3PIZ 3PJ1 3PJ2 3PJ3
Enriched GO Terms of Interacting Partners?
Tagcloud ?
bcr  btk  card11  cll  connected  crosstalk  dlbcl  dys  emphasise  encouraging  fosfamatinib  gab1  ibrutinib  idelalisib  integrins  interconnected  intimately  leukaemia  lymphocytic  lymphomas  lyn  micrornas  phosphatases  physiology  shp  signalling  syk  tonic  underscored 
adhesion  allergic  appear  asthma  compares  contrasts  csf  degranulation  describes  emerging  eosinophil  eosinophils  exert  gm  granulocyte  hematopoiesis  heterodimer  jak  lyn  macrophage  paramount  propagates  raf  segregation  seminal  shp  stat  syk  transduction 
Tagcloud (Difference) ?
bcr  card11  cll  connected  crosstalk  dlbcl  dys  emphasise  encouraging  fosfamatinib  gab1  ibrutinib  idelalisib  integrins  interconnected  intimately  leukaemia  lymphocytic  lymphomas  micrornas  phosphatases  physiology  signalling  tonic  underscored 
adhesion  allergic  appear  asthma  compares  contrasts  csf  degranulation  describes  emerging  eosinophil  eosinophils  exert  gm  granulocyte  hematopoiesis  heterodimer  jak  macrophage  paramount  propagates  raf  segregation  seminal  stat  transduction 
Tagcloud (Intersection) ?
btk  lyn  shp  syk