TXNDC11 and KRT18

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		TXNDC11	KRT18
Gene Name		thioredoxin domain containing 11	keratin 18, type I
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane	Nucleolus Cytoplasm Microtubule Organizing Center Intermediate Filament Centriolar Satellite Keratin Filament Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome Cell Periphery
	Molecular Function	Protein Disulfide Isomerase Activity Protein Binding	Structural Molecule Activity Protein Binding Poly(A) RNA Binding Scaffold Protein Binding
	Biological Process	Protein Folding Response To Endoplasmic Reticulum Stress Cell Redox Homeostasis	Cell Cycle Anatomical Structure Morphogenesis Viral Process Tumor Necrosis Factor-mediated Signaling Pathway Golgi To Plasma Membrane CFTR Protein Transport Negative Regulation Of Apoptotic Process Intermediate Filament Cytoskeleton Organization Extrinsic Apoptotic Signaling Pathway Hepatocyte Apoptotic Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		17 interactors: ACAA1 ATXN7 CDKN1A DUOX1 DUOX2 GFI1B HSP90B1 KRT15 KRT18 NOS3 ORC5 RACGAP1 RPS19 RPS6KA5 SOCS3 STAT5A TPO	73 interactors: BBS1 BBS2 BBS4 BBS7 CAMK2A CASP3 CASP6 CASP7 CASP8 CBL CCDC146 CCDC85B CCNI CDC5L CDK1 COL17A1 DEDD DNAJB6 EGFR EP300 EXOC8 FRAT1 GIT2 GOLGA2 GRN HAUS1 HGS HRAS HSPA1A HSPA4 HSPA5 IKBKG KPNA2 KRT15 KRT5 KRT72 KRT8 LDOC1 MAPK14 NME7 ORC5 PDE4DIP PIAS4 PKD1 PKP2 PKP3 PNN POT1 PRKCA PRKCE RAF1 RHPN2 RPS6KA3 SERPINE1 SHC1 SMARCD1 SUMO1 SVIL TCHP TNFRSF1B TRADD TUBG1 TUBGCP4 TXN2 TXNDC11 UPF2 USH2A YTHDC1 YWHAB YWHAE YWHAG YWHAH YWHAZ
Entrez ID		51061	3875
HPRD ID		07125	01020
Ensembl ID		ENSG00000153066	ENSG00000111057
Uniprot IDs		Q6PKC3	P05783
PDB IDs
Enriched GO Terms of Interacting Partners?		Thyroid Hormone Generation Hydrogen Peroxide Catabolic Process Thyroid Hormone Metabolic Process Cytokine-mediated Signaling Pathway Regulation Of Innate Immune Response Reactive Oxygen Species Metabolic Process Anatomical Structure Development Cuticle Development Cellular Response To Organic Substance Hydrogen Peroxide Metabolic Process Cellular Response To Cytokine Stimulus Developmental Process Immune System Process Response To Cytokine Hormone Biosynthetic Process Positive Regulation Of Innate Immune Response Response To Organonitrogen Compound Response To Organic Substance Regulation Of Immune Response Cellular Modified Amino Acid Metabolic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Phenol-containing Compound Metabolic Process Negative Regulation Of Cell Death Multicellular Organismal Development Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway JAK-STAT Cascade Involved In Growth Hormone Signaling Pathway Catabolic Process Growth Hormone Receptor Signaling Pathway System Development Response To Organophosphorus Cellular Response To Growth Hormone Stimulus Regulation Of Immune System Process Response To Stress Response To Purine-containing Compound Hormone Metabolic Process Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Immune System Process Regulation Of Apoptotic Process Regulation Of Phosphorus Metabolic Process Response To Growth Hormone Regulation Of Protein Metabolic Process Regulation Of Cell Death Organ Development JAK-STAT Cascade Cell Surface Receptor Signaling Pathway Organelle Organization Histone H2A-S1 Phosphorylation Cytokinesis, Initiation Of Separation Actomyosin Contractile Ring Assembly	Apoptotic Process Programmed Cell Death Cell Death Death Apoptotic Signaling Pathway Intrinsic Apoptotic Signaling Pathway Regulation Of Cell Death Regulation Of Protein Metabolic Process Cellular Response To Organic Substance Neurotrophin TRK Receptor Signaling Pathway Regulation Of Apoptotic Process Neurotrophin Signaling Pathway Regulation Of Cellular Protein Metabolic Process Response To Organic Substance Cellular Response To Growth Factor Stimulus Response To Growth Factor Cell Surface Receptor Signaling Pathway Epidermal Growth Factor Receptor Signaling Pathway Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway ERBB Signaling Pathway Cellular Component Assembly Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Cell Communication Positive Regulation Of Cellular Protein Metabolic Process Membrane Organization Signal Transduction Positive Regulation Of Signal Transduction Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Signaling Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Organelle Organization Innate Immune Response Fibroblast Growth Factor Receptor Signaling Pathway Regulation Of Signal Transduction Positive Regulation Of Protein Metabolic Process Positive Regulation Of Transport Anatomical Structure Development Mitotic Cell Cycle Regulation Of Cellular Component Organization Regulation Of Signaling Mitotic Cell Cycle Phase Transition Cellular Response To Fibroblast Growth Factor Stimulus Cell Cycle Phase Transition Enzyme Linked Receptor Protein Signaling Pathway Response To Fibroblast Growth Factor Developmental Process Defense Response Regulation Of Proteolysis Cellular Protein Localization Cellular Response To Stimulus
Tagcloud ?			actg2 adenomatous archived b4ganlt2 bank casp3 cdx1 cdx2 classifier cnn1 col1a1 custom ezr fsp1 genomelab hcellmarkerplex house hybridisation incorporates lgr5 ms4a12 muc2 mucin nox1 ntn1 polyp signatures slc9a2 vwf
Tagcloud (Difference) ?			actg2 adenomatous archived b4ganlt2 bank casp3 cdx1 cdx2 classifier cnn1 col1a1 custom ezr fsp1 genomelab hcellmarkerplex house hybridisation incorporates lgr5 ms4a12 muc2 mucin nox1 ntn1 polyp signatures slc9a2 vwf
Tagcloud (Intersection) ?