TXNDC11 and RACGAP1

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		TXNDC11	RACGAP1
Gene Name		thioredoxin domain containing 11	Rac GTPase activating protein 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane	Acrosomal Vesicle Nucleus Nucleoplasm Cytosol Microtubule Midbody Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane Cleavage Furrow Spindle Midzone Extracellular Vesicular Exosome Mitotic Spindle Centralspindlin Complex
	Molecular Function	Protein Disulfide Isomerase Activity Protein Binding	GTPase Activator Activity Protein Binding Phosphatidylinositol-3,4,5-trisphosphate Binding Microtubule Binding Protein Kinase Binding Alpha-tubulin Binding Gamma-tubulin Binding Metal Ion Binding Beta-tubulin Binding
	Biological Process	Protein Folding Response To Endoplasmic Reticulum Stress Cell Redox Homeostasis	Mitotic Cytokinesis Actomyosin Contractile Ring Assembly Microtubule-based Movement Cytokinesis, Initiation Of Separation Small GTPase Mediated Signal Transduction Spermatogenesis Neuroblast Proliferation Blood Coagulation Sulfate Transport Embryo Development Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Positive Regulation Of Cytokinesis Positive Regulation Of GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction Mitotic Spindle Midzone Assembly Regulation Of Attachment Of Spindle Microtubules To Kinetochore
Pathways			Rho GTPase cycle Signaling by Rho GTPases MHC class II antigen presentation Kinesins Factors involved in megakaryocyte development and platelet production Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		17 interactors: ACAA1 ATXN7 CDKN1A DUOX1 DUOX2 GFI1B HSP90B1 KRT15 KRT18 NOS3 ORC5 RACGAP1 RPS19 RPS6KA5 SOCS3 STAT5A TPO	26 interactors: AURKB CDK1 CHN2 ECT2 KIF23 MAP3K10 MAP3K4 MORF4L1 MPRIP NRAS PPP2CA PPP2R4 PPP2R5E PRC1 PRSS23 RND2 SH3RF1 SLC16A10 SLC26A8 TANK TUBA4A TUBG1 TXNDC11 VAV1 YWHAB YWHAG
Entrez ID		51061	29127
HPRD ID		07125	05402
Ensembl ID		ENSG00000153066	ENSG00000161800
Uniprot IDs		Q6PKC3	B2RE34 Q9H0H5
PDB IDs			2OVJ 4B6D
Enriched GO Terms of Interacting Partners?		Thyroid Hormone Generation Hydrogen Peroxide Catabolic Process Thyroid Hormone Metabolic Process Cytokine-mediated Signaling Pathway Regulation Of Innate Immune Response Reactive Oxygen Species Metabolic Process Anatomical Structure Development Cuticle Development Cellular Response To Organic Substance Hydrogen Peroxide Metabolic Process Cellular Response To Cytokine Stimulus Developmental Process Immune System Process Response To Cytokine Hormone Biosynthetic Process Positive Regulation Of Innate Immune Response Response To Organonitrogen Compound Response To Organic Substance Regulation Of Immune Response Cellular Modified Amino Acid Metabolic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Phenol-containing Compound Metabolic Process Negative Regulation Of Cell Death Multicellular Organismal Development Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway JAK-STAT Cascade Involved In Growth Hormone Signaling Pathway Catabolic Process Growth Hormone Receptor Signaling Pathway System Development Response To Organophosphorus Cellular Response To Growth Hormone Stimulus Regulation Of Immune System Process Response To Stress Response To Purine-containing Compound Hormone Metabolic Process Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Immune System Process Regulation Of Apoptotic Process Regulation Of Phosphorus Metabolic Process Response To Growth Hormone Regulation Of Protein Metabolic Process Regulation Of Cell Death Organ Development JAK-STAT Cascade Cell Surface Receptor Signaling Pathway Organelle Organization Histone H2A-S1 Phosphorylation Cytokinesis, Initiation Of Separation Actomyosin Contractile Ring Assembly	Activation Of MAPKK Activity Mitotic Cell Cycle Process Mitotic Cell Cycle Cell Cycle Cell Cycle Process Mitotic Spindle Elongation Intracellular Signal Transduction Mitotic Spindle Organization Regulation Of Catalytic Activity Spindle Organization Microtubule Cytoskeleton Organization Activation Of Protein Kinase Activity Positive Regulation Of Protein Kinase Activity Positive Regulation Of Kinase Activity Regulation Of Protein Kinase Activity Fibroblast Growth Factor Receptor Signaling Pathway Regulation Of Kinase Activity Regulation Of Apoptotic Process Regulation Of Phosphorus Metabolic Process Positive Regulation Of Transferase Activity Positive Regulation Of Catalytic Activity Cellular Response To Fibroblast Growth Factor Stimulus Response To Fibroblast Growth Factor Regulation Of Cell Death Regulation Of MAPK Cascade Small GTPase Mediated Signal Transduction Positive Regulation Of Protein Modification Process Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Cytokinesis MAPK Cascade Vascular Endothelial Growth Factor Receptor Signaling Pathway Regulation Of Phosphorylation Apoptotic Process Regulation Of Intracellular Signal Transduction Programmed Cell Death Protein Complex Assembly Positive Regulation Of Protein Phosphorylation Positive Regulation Of Cytokinesis Regulation Of Signal Transduction G2/M Transition Of Mitotic Cell Cycle Cell Death Death Regulation Of Protein Phosphorylation Microtubule-based Process Signal Transduction By Phosphorylation Positive Regulation Of Cellular Protein Metabolic Process Cytoskeleton Organization Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Protein Dephosphorylation
Tagcloud ?			anapc1 antagonizes canonical cd40l cdk6 chip combine consequence crosstalk dek ezh2 ikkalpha involves kappab2 lymphocytic microenvironment nemo nik p100 p21waf1 p52 polycomb psma5 rel rela relb retinoblastoma route senescent
Tagcloud (Difference) ?			anapc1 antagonizes canonical cd40l cdk6 chip combine consequence crosstalk dek ezh2 ikkalpha involves kappab2 lymphocytic microenvironment nemo nik p100 p21waf1 p52 polycomb psma5 rel rela relb retinoblastoma route senescent
Tagcloud (Intersection) ?