TXNDC11 and RAB2B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TXNDC11	RAB2B
Description		thioredoxin domain containing 11	RAB2B, member RAS oncogene family
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane	Golgi Membrane Autophagosome Membrane Acrosomal Vesicle Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Plasma Membrane Membrane Cytoplasmic Vesicle Extracellular Exosome
	Molecular Function	Protein Binding	Nucleotide Binding GTPase Activity Protein Binding GTP Binding Hydrolase Activity Metal Ion Binding
	Biological Process		Golgi Organization Protein Transport Vesicle-mediated Transport Macroautophagy Positive Regulation Of Type I Interferon Production Innate Immune Response Positive Regulation Of Exocytosis Defense Response To Virus
Pathways		Thyroxine biosynthesis	RAB geranylgeranylation
Drugs
Diseases
GWAS		Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Plasma renin activity levels ( 29650764) Red cell distribution width ( 32888494) Rheumatoid arthritis ( 24390342 30423114) Serum alkaline phosphatase levels ( 33547301) Triglyceride levels ( 32203549) Weight ( 28552196)	Height ( 31562340)
Interacting Genes		22 interacting genes: ACAA1 ATXN7 CDKN1A DUOX1 DUOX2 GFI1B HSP90B1 KLHL38 KRT15 KRT18 MKRN3 NOS3 NRIP1 ORC5 RAB2B RACGAP1 RPS19 RPS6KA5 SOCS3 STAT5A TPO ZNF417	20 interacting genes: ADAMTSL4 APP BLZF1 CRK FAM114A1 FAM114A2 GARIN4 GARIN6 GOLGA2 ICA1 MEOX2 NOP2 SGSM2 SMAD1 SMAD4 SRSF11 STAMBPL1 TBX19 TXNDC11 VRTN
Entrez ID		51061	84932
HPRD ID		07125	06312
Ensembl ID		ENSG00000153066	ENSG00000129472
Uniprot IDs		Q6PKC3	B4DUD4 Q8WUD1
PDB IDs			2A5J
Enriched GO Terms of Interacting Partners?		Superoxide-generating NAD(P)H Oxidase Activity Thyroid Hormone Generation Hydrogen Peroxide Catabolic Process Cellular Oxidant Detoxification Thyroid Hormone Metabolic Process Cuticle Development Reactive Oxygen Species Metabolic Process Peroxidase Activity Hydrogen Peroxide Metabolic Process Cytokine-mediated Signaling Pathway Cellular Detoxification Heme Binding Hormone Biosynthetic Process Ovulation Cycle Process Superoxide Metabolic Process Hydrogen Peroxide Biosynthetic Process Scaffold Protein Binding NAD(P)H Oxidase H2O2-forming Activity Erythrocyte Differentiation Ovulation Phenol-containing Compound Metabolic Process Reactive Oxygen Species Biosynthetic Process NADPH Oxidase Complex Superoxide Anion Generation Nuclear Matrix Regulation Of Wound Healing Lipid Storage Response To Purine-containing Compound Acetate CoA-transferase Activity Phenylacetate Catabolic Process NADP Binding Modified Amino Acid Metabolic Process Iodide Peroxidase Activity Ovarian Follicle Rupture Histone H2AS1 Kinase Activity Regulation Of Response To Wounding Protein Kinase Inhibitor Activity Tissue Morphogenesis Catabolic Process Cytosol Cellular Response To Cytokine Stimulus Hormone Metabolic Process	Heteromeric SMAD Protein Complex Embryonic Pattern Specification SMAD Protein Complex Regulation Of MiRNA Transcription Regulation Of MiRNA Metabolic Process Response To Yeast I-SMAD Binding Cardiac Conduction System Development Cellular Response To Growth Factor Stimulus Golgi Organization SMAD Protein Signal Transduction
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