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RGS2 and KIAA1377
Number of citations of the paper that reports this interaction (PMID
21900206
)
27
Data Source:
BioGRID
(two hybrid)
RGS2
KIAA1377
Gene Name
regulator of G-protein signaling 2
KIAA1377
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleolus
Cytoplasm
Mitochondrion
Cytosol
Plasma Membrane
Cytoplasmic Side Of Plasma Membrane
Neuron Projection
Cytoplasm
Centrosome
Midbody
Ciliary Base
Molecular Function
GTPase Activator Activity
Protein Binding
Calmodulin Binding
Beta-tubulin Binding
Protein Binding
Biological Process
Regulation Of Translation
Cell Cycle
Spermatogenesis
Regulation Of G-protein Coupled Receptor Protein Signaling Pathway
Negative Regulation Of Phospholipase Activity
Negative Regulation Of Cardiac Muscle Hypertrophy
Positive Regulation Of Microtubule Polymerization
Termination Of G-protein Coupled Receptor Signaling Pathway
Negative Regulation Of MAP Kinase Activity
Positive Regulation Of GTPase Activity
Negative Regulation Of CAMP-mediated Signaling
Negative Regulation Of G-protein Coupled Receptor Protein Signaling Pathway
Brown Fat Cell Differentiation
Relaxation Of Cardiac Muscle
Relaxation Of Vascular Smooth Muscle
Positive Regulation Of Cardiac Muscle Contraction
Regulation Of Adrenergic Receptor Signaling Pathway
Mitotic Spindle Organization
Cytoplasmic Microtubule Organization
Cilium Assembly
Pathways
G alpha (q) signalling events
G alpha (q) signalling events
Signaling by GPCR
GPCR downstream signaling
Gastrin-CREB signalling pathway via PKC and MAPK
Drugs
Diseases
GWAS
Protein-Protein Interactions
58 interactors:
ADCY5
ADRA1A
ADRB2
ARFGAP1
BBS10
CALM1
CHD3
CLTA
COMT
COPB1
COPB2
CRMP1
CTSB
DDR1
DUSP21
DYNLL1
EIF3L
FZD5
GDE1
GIT1
GNA15
GNAI3
GNAQ
GNAS
HAUS5
HSPA8
IER3IP1
KIAA1377
KLK8
LIG1
LRFN1
METTL18
MON1A
MTUS2
NINL
NIPSNAP1
PARK2
PPP1R9B
PRKCA
PRKCB
PRKCG
PRKCSH
PRKG1
RAB2A
RABAC1
RAP1B
REEP5
RIN3
SCN5A
TSPAN15
TUBB2B
UBC
VPS29
WDR74
XRCC6
ZBTB48
ZNF579
ZYX
86 interactors:
AIMP2
AKTIP
ARIH2
ATP6V1F
ATRX
BMI1
BRD1
C11orf58
CDKN2B
CRCT1
CSTF2
DGCR6
DISC1
DLEU1
DNM1
DUSP12
DUSP23
EIF2S2
EIF6
EPN1
FAM118B
FAM134A
FEZ1
FGFR3
FXR1
GEMIN7
GET4
GIT1
GOLGB1
GPRASP2
GSTO1
HMOX2
HTT
ING5
KAT5
KAT7
KIF15
KLHL20
LAMTOR5
LPL
LRRC1
LUC7L2
MAD2L1BP
MAPK9
MRPS6
NAP1L5
NAT9
NPM3
NSF
NUDT21
ODF2L
OFD1
PBK
PDCD5
PFDN1
PIK3R3
PMF1
POLD1
POLR2M
PPP1CA
PPP1CC
PRKRA
PTPRS
RAB27A
RAN
RBM23
RGS2
RIF1
ROGDI
RPA2
RUVBL1
SAT1
SNRPG
SPDL1
STAU2
TFG
TNFRSF14
TNFSF11
TOMM20
TTR
TXNDC9
VIM
YAE1D1
YWHAZ
ZBED8
ZNF24
Entrez ID
5997
57562
HPRD ID
02917
17212
Ensembl ID
ENSG00000116741
ENSG00000110318
Uniprot IDs
P41220
Q9P2H0
PDB IDs
2AF0
2V4Z
4EKC
4EKD
Enriched GO Terms of Interacting Partners
?
Activation Of Phospholipase C Activity
Positive Regulation Of Phospholipase C Activity
Positive Regulation Of Phospholipase Activity
Platelet Activation
Regulation Of Phospholipase Activity
Positive Regulation Of Lipase Activity
Regulation Of Catalytic Activity
Regulation Of Body Fluid Levels
Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway
Response To Wounding
Blood Coagulation
G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger
Hemostasis
Wound Healing
Cell-cell Signaling
Regulation Of Phosphorus Metabolic Process
Regulation Of Adenylate Cyclase Activity
Nervous System Development
Regulation Of Cyclase Activity
Activation Of Adenylate Cyclase Activity
Signaling
Response To Stress
Neurotrophin Signaling Pathway
Cell Communication
Regulation Of Phosphorylation
Dopamine Receptor Signaling Pathway
Positive Regulation Of Catalytic Activity
Developmental Process
Positive Regulation Of Adenylate Cyclase Activity
Regulation Of Kinase Activity
Response To Organic Substance
Cellular Response To Stimulus
Regulation Of Muscle Contraction
Anatomical Structure Development
Regulation Of CAMP Biosynthetic Process
Epidermal Growth Factor Receptor Signaling Pathway
ERBB Signaling Pathway
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
COPI-coated Vesicle Budding
COPI Coating Of Golgi Vesicle
Positive Regulation Of Hydrolase Activity
Cell Activation
Membrane Organization
Regulation Of CAMP Metabolic Process
Regulation Of Protein Phosphorylation
System Development
Positive Regulation Of Lyase Activity
Enzyme Linked Receptor Protein Signaling Pathway
Golgi Vesicle Budding
Adrenergic Receptor Signaling Pathway
Organelle Organization
Cell Cycle
Mitotic Cell Cycle
Histone Acetylation
Internal Peptidyl-lysine Acetylation
Peptidyl-lysine Acetylation
Internal Protein Amino Acid Acetylation
Protein Acetylation
Cellular Metabolic Process
Mitotic Cell Cycle Process
Cellular Process
Response To Light Stimulus
Response To Radiation
Triglyceride Catabolic Process
Gene Expression
Positive Regulation Of Apoptotic Signaling Pathway
Organelle Localization
Acylglycerol Catabolic Process
Endomembrane System Organization
Establishment Of Organelle Localization
Cell Cycle Process
Positive Regulation Of Signal Transduction
Peptidyl-lysine Modification
Endosome Organization
Protein Localization To Organelle
Positive Regulation Of Metabolic Process
Anatomical Structure Development
System Development
Regulation Of Signal Transduction
Termination Of RNA Polymerase II Transcription
Cytoplasmic Transport
Programmed Cell Death
Chromosome Organization
Cell Division
Ribosomal Subunit Export From Nucleus
Cell Death
Regulation Of Signaling
Cellular Response To Stimulus
Death
Histone H3 Acetylation
Enzyme Linked Receptor Protein Signaling Pathway
Regulation Of Protein Ubiquitination
Mitotic Nuclear Division
Ribonucleoprotein Complex Biogenesis
Response To Abiotic Stimulus
Positive Regulation Of Striated Muscle Contraction
Cellular Response To Organic Substance
RNA Metabolic Process
Organ Development
Neurotransmitter Uptake
Tagcloud
?
3t3
adipocyte
already
arrested
beginning
cloned
clones
differentially
earliest
ebpalpha
hif
hsp105
inducers
l1
master
mrnas
nih
nineteen
place
ppargamma2
preadipocyte
proliferating
regulators
rho
seemed
steps
takes
tc10
vdr
Tagcloud (Difference)
?
3t3
adipocyte
already
arrested
beginning
cloned
clones
differentially
earliest
ebpalpha
hif
hsp105
inducers
l1
master
mrnas
nih
nineteen
place
ppargamma2
preadipocyte
proliferating
regulators
rho
seemed
steps
takes
tc10
vdr
Tagcloud (Intersection)
?