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CHMP2A and DOCK8
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
CHMP2A
DOCK8
Gene Name
charged multivesicular body protein 2A
dedicator of cytokinesis 8
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytosol
Membrane
Late Endosome Membrane
Extracellular Vesicular Exosome
Cytosol
Membrane
Cell Leading Edge
Molecular Function
Protein Binding
Protein Domain Specific Binding
Guanyl-nucleotide Exchange Factor Activity
Protein Binding
Biological Process
Cell Separation After Cytokinesis
Nucleus Organization
Vacuolar Transport
Mitotic Metaphase Plate Congression
Regulation Of Centrosome Duplication
Protein Transport
Viral Process
Endosomal Transport
Viral Life Cycle
Viral Budding Via Host ESCRT Complex
Establishment Of Protein Localization
Regulation Of Viral Process
Negative Regulation Of Cell Death
Membrane Organization
Regulation Of Mitotic Spindle Assembly
Positive Regulation Of Viral Release From Host Cell
Positive Regulation Of Exosomal Secretion
Negative Regulation Of Centriole Elongation
Immunological Synapse Formation
Small GTPase Mediated Signal Transduction
Blood Coagulation
Dendritic Cell Migration
Positive Regulation Of GTPase Activity
Memory T Cell Proliferation
Negative Regulation Of T Cell Apoptotic Process
Pathways
HIV Life Cycle
Budding and maturation of HIV virion
HIV Infection
Endosomal Sorting Complex Required For Transport (ESCRT)
Late Phase of HIV Life Cycle
Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS
Mean platelet volume (
22139419
)
Obesity-related traits (
23251661
)
Protein-Protein Interactions
12 interactors:
CHMP3
DOCK8
E2F4
EIF2B5
MITD1
NOL4
STAMBP
TGFB3
USP54
USP8
VPS4A
VPS4B
25 interactors:
BYSL
CARHSP1
CDC42
CHMP2A
DGCR6
EXOSC5
FAM124A
FAM161A
FANCL
FBXL12
HBZ
KRT40
LRCH1
LRCH3
MED30
MEOX2
MRPL38
MTG1
RAC1
RHOJ
RHOQ
RTP5
SMAD2
ZFC3H1
ZNF581
Entrez ID
27243
81704
HPRD ID
12520
10920
Ensembl ID
ENSG00000130724
ENSG00000107099
Uniprot IDs
O43633
E2J6M5
E2J6M6
Q8NF50
PDB IDs
Enriched GO Terms of Interacting Partners
?
Cell Separation After Cytokinesis
Cell Division
Cytokinesis
Mitotic Cell Cycle Process
Mitotic Cell Cycle
Mitotic Cytokinesis
Ubiquitin-independent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway
Cell Cycle Process
Viral Budding Via Host ESCRT Complex
Positive Regulation Of Viral Release From Host Cell
Viral Budding
Positive Regulation Of Exosomal Secretion
Regulation Of Exosomal Secretion
Cell Cycle
Regulation Of Viral Release From Host Cell
Virion Assembly
Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway
Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Mitotic Metaphase Plate Congression
Viral Life Cycle
Proteolysis Involved In Cellular Protein Catabolic Process
Cellular Protein Catabolic Process
Endosome Organization
Metaphase Plate Congression
Endosomal Transport
Protein Catabolic Process
Regulation Of Centrosome Duplication
Establishment Of Chromosome Localization
Regulation Of Cell Division
Regulation Of Centrosome Cycle
Proteolysis
Positive Regulation Of Exocytosis
Positive Regulation Of Secretion
Cellular Macromolecule Catabolic Process
Negative Regulation Of Exosomal Secretion
Memory T Cell Proliferation
Positive Regulation Of Centriole Elongation
Positive Regulation Of Viral Process
Mitotic Sister Chromatid Segregation
Membrane Budding
Sister Chromatid Segregation
Negative Regulation Of Cell Death
Positive Regulation Of Centriole Replication
Detection Of Hypoxia
Endosome To Lysosome Transport Via Multivesicular Body Sorting Pathway
Uterine Wall Breakdown
Ovulation Cycle Process
Vacuole Organization
Protein Deubiquitination
Regulation Of Cell Morphogenesis
Regulation Of Cell Projection Assembly
Positive Regulation Of Phosphatidylinositol 3-kinase Activity
Positive Regulation Of Substrate Adhesion-dependent Cell Spreading
Positive Regulation Of Cell Morphogenesis Involved In Differentiation
Regulation Of Substrate Adhesion-dependent Cell Spreading
Anatomical Structure Morphogenesis
Posttranscriptional Regulation Of Gene Expression
Ribosome Biogenesis
Regulation Of Cellular Component Organization
Regulation Of Cytoskeleton Organization
Regulation Of Organelle Organization
Regulation Of Filopodium Assembly
Regulation Of Phosphatidylinositol 3-kinase Activity
Negative Regulation Of Centriole Elongation
Positive Regulation Of Macromolecule Biosynthetic Process
Regulation Of Lipid Kinase Activity
Anatomical Structure Formation Involved In Morphogenesis
Actin Cytoskeleton Organization
Positive Regulation Of Cellular Biosynthetic Process
Positive Regulation Of DNA Replication
Small GTPase Mediated Signal Transduction
Positive Regulation Of Cell Projection Organization
Cell Projection Assembly
Embryonic Olfactory Bulb Interneuron Precursor Migration
Negative Regulation Of Interleukin-23 Production
Positive Regulation Of Nodal Signaling Pathway Involved In Determination Of Lateral Mesoderm Left/right Asymmetry
Positive Regulation Of Hair Follicle Cell Proliferation
Actin Filament-based Process
T Cell Costimulation
Positive Regulation Of Cellular Component Biogenesis
Ribonucleoprotein Complex Biogenesis
Embryonic Pattern Specification
Regulation Of Protein Complex Assembly
Regulation Of Nodal Signaling Pathway Involved In Determination Of Lateral Mesoderm Left/right Asymmetry
Engulfment Of Apoptotic Cell
Submandibular Salivary Gland Formation
Actin Filament Branching
Zygotic Specification Of Dorsal/ventral Axis
Regulation Of Small GTPase Mediated Signal Transduction
Anatomical Structure Development
Ephrin Receptor Signaling Pathway
Intracellular Signal Transduction
Vascular Endothelial Growth Factor Receptor Signaling Pathway
Mast Cell Chemotaxis
Regulation Of Hair Follicle Cell Proliferation
Positive Regulation Of Synapse Structural Plasticity
Palate Development
Positive Regulation Of Cell-substrate Adhesion
Regulation Of Mitotic Nuclear Division
Tagcloud
?
akr1c4
anomalies
apparently
array
balanced
bases
cdon
cgh
chrna7
confirming
dd
diagnoses
gata3
id
indistinguishable
inherited
intellectual
karyotype
karyotyping
mb
mca
nr2f2
overlooked
prenatal
pws
rearrangements
spanning
tier
tp63
Tagcloud (Difference)
?
akr1c4
anomalies
apparently
array
balanced
bases
cdon
cgh
chrna7
confirming
dd
diagnoses
gata3
id
indistinguishable
inherited
intellectual
karyotype
karyotyping
mb
mca
nr2f2
overlooked
prenatal
pws
rearrangements
spanning
tier
tp63
Tagcloud (Intersection)
?