DOCK8 and ZFC3H1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		DOCK8	ZFC3H1
Gene Name		dedicator of cytokinesis 8	zinc finger, C3H1-type containing
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Membrane Cell Leading Edge	Extracellular Space Intracellular
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding	Protein Binding Poly(A) RNA Binding Metal Ion Binding
	Biological Process	Immunological Synapse Formation Small GTPase Mediated Signal Transduction Blood Coagulation Dendritic Cell Migration Positive Regulation Of GTPase Activity Memory T Cell Proliferation Negative Regulation Of T Cell Apoptotic Process	RNA Processing
Pathways		Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS		Mean platelet volume ( 22139419) Obesity-related traits ( 23251661)
Protein-Protein Interactions		25 interactors: BYSL CARHSP1 CDC42 CHMP2A DGCR6 EXOSC5 FAM124A FAM161A FANCL FBXL12 HBZ KRT40 LRCH1 LRCH3 MED30 MEOX2 MRPL38 MTG1 RAC1 RHOJ RHOQ RTP5 SMAD2 ZFC3H1 ZNF581	14 interactors: APP CCDC57 CCDC85B CEP70 CSNK2A1 DOCK8 GOLGA2 HNRNPK KHDRBS2 MTUS2 NINL SPAG5 TRIM27 ZDHHC17
Entrez ID		81704	196441
HPRD ID		10920	14489
Ensembl ID		ENSG00000107099	ENSG00000133858
Uniprot IDs		E2J6M5 E2J6M6 Q8NF50	O60293
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Cell Morphogenesis Regulation Of Cell Projection Assembly Positive Regulation Of Phosphatidylinositol 3-kinase Activity Positive Regulation Of Substrate Adhesion-dependent Cell Spreading Positive Regulation Of Cell Morphogenesis Involved In Differentiation Regulation Of Substrate Adhesion-dependent Cell Spreading Anatomical Structure Morphogenesis Posttranscriptional Regulation Of Gene Expression Ribosome Biogenesis Regulation Of Cellular Component Organization Regulation Of Cytoskeleton Organization Regulation Of Organelle Organization Regulation Of Filopodium Assembly Regulation Of Phosphatidylinositol 3-kinase Activity Negative Regulation Of Centriole Elongation Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Lipid Kinase Activity Anatomical Structure Formation Involved In Morphogenesis Actin Cytoskeleton Organization Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of DNA Replication Small GTPase Mediated Signal Transduction Positive Regulation Of Cell Projection Organization Cell Projection Assembly Embryonic Olfactory Bulb Interneuron Precursor Migration Negative Regulation Of Interleukin-23 Production Positive Regulation Of Nodal Signaling Pathway Involved In Determination Of Lateral Mesoderm Left/right Asymmetry Positive Regulation Of Hair Follicle Cell Proliferation Actin Filament-based Process T Cell Costimulation Positive Regulation Of Cellular Component Biogenesis Ribonucleoprotein Complex Biogenesis Embryonic Pattern Specification Regulation Of Protein Complex Assembly Regulation Of Nodal Signaling Pathway Involved In Determination Of Lateral Mesoderm Left/right Asymmetry Engulfment Of Apoptotic Cell Submandibular Salivary Gland Formation Actin Filament Branching Zygotic Specification Of Dorsal/ventral Axis Regulation Of Small GTPase Mediated Signal Transduction Anatomical Structure Development Ephrin Receptor Signaling Pathway Intracellular Signal Transduction Vascular Endothelial Growth Factor Receptor Signaling Pathway Mast Cell Chemotaxis Regulation Of Hair Follicle Cell Proliferation Positive Regulation Of Synapse Structural Plasticity Palate Development Positive Regulation Of Cell-substrate Adhesion Regulation Of Mitotic Nuclear Division	Mitotic Cell Cycle Mitotic Cell Cycle Process Cell Cycle Memory T Cell Proliferation Regulation Of Chromosome Segregation Regulation Of Lipid Transport By Positive Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Interleukin-2 Secretion Synaptic Growth At Neuromuscular Junction Cell Cycle Process Collateral Sprouting In Absence Of Injury G2/M Transition Of Mitotic Cell Cycle Regulation Of Cellular Component Organization Cell Recognition
Tagcloud ?		akr1c4 anomalies apparently array balanced bases cdon cgh chrna7 confirming dd diagnoses gata3 id indistinguishable inherited intellectual karyotype karyotyping mb mca nr2f2 overlooked prenatal pws rearrangements spanning tier tp63
Tagcloud (Difference) ?		akr1c4 anomalies apparently array balanced bases cdon cgh chrna7 confirming dd diagnoses gata3 id indistinguishable inherited intellectual karyotype karyotyping mb mca nr2f2 overlooked prenatal pws rearrangements spanning tier tp63
Tagcloud (Intersection) ?