CHMP2A and CHMP3

Number of citations of the paper that reports this interaction (PMID 16730941)
46

Data Source:
BioGRID (affinity chromatography technology, two hybrid)
HPRD (two hybrid)

		CHMP2A	CHMP3
Gene Name		charged multivesicular body protein 2A	charged multivesicular body protein 3
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Membrane Late Endosome Membrane Extracellular Vesicular Exosome	Cytosol Late Endosome Membrane Extracellular Vesicular Exosome
	Molecular Function	Protein Binding Protein Domain Specific Binding	Protein Binding
	Biological Process	Cell Separation After Cytokinesis Nucleus Organization Vacuolar Transport Mitotic Metaphase Plate Congression Regulation Of Centrosome Duplication Protein Transport Viral Process Endosomal Transport Viral Life Cycle Viral Budding Via Host ESCRT Complex Establishment Of Protein Localization Regulation Of Viral Process Negative Regulation Of Cell Death Membrane Organization Regulation Of Mitotic Spindle Assembly Positive Regulation Of Viral Release From Host Cell Positive Regulation Of Exosomal Secretion Negative Regulation Of Centriole Elongation	Cell Separation After Cytokinesis Apoptotic Process Nucleus Organization Vacuolar Transport Mitotic Metaphase Plate Congression Regulation Of Centrosome Duplication Protein Transport Viral Process Endosomal Transport Viral Life Cycle Regulation Of Viral Process Membrane Organization Regulation Of Mitotic Spindle Assembly Positive Regulation Of Viral Release From Host Cell Regulation Of Exosomal Secretion
Pathways		HIV Life Cycle Budding and maturation of HIV virion HIV Infection Endosomal Sorting Complex Required For Transport (ESCRT) Late Phase of HIV Life Cycle	HIV Life Cycle Budding and maturation of HIV virion HIV Infection Endosomal Sorting Complex Required For Transport (ESCRT) Late Phase of HIV Life Cycle
Drugs
Diseases
GWAS
Protein-Protein Interactions		12 interactors: CHMP3 DOCK8 E2F4 EIF2B5 MITD1 NOL4 STAMBP TGFB3 USP54 USP8 VPS4A VPS4B	12 interactors: APP CHMP2A CHMP2B CHMP4A CHMP4B IGFBP7 RAB11A SMAD1 SMAD5 STAMBP TNPO3 VAV2
Entrez ID		27243	51652
HPRD ID		12520	15650
Ensembl ID		ENSG00000130724	ENSG00000115561
Uniprot IDs		O43633	Q9Y3E7
PDB IDs			2GD5 2XZE 3FRT 3FRV
Enriched GO Terms of Interacting Partners?		Cell Separation After Cytokinesis Cell Division Cytokinesis Mitotic Cell Cycle Process Mitotic Cell Cycle Mitotic Cytokinesis Ubiquitin-independent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Cell Cycle Process Viral Budding Via Host ESCRT Complex Positive Regulation Of Viral Release From Host Cell Viral Budding Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Cell Cycle Regulation Of Viral Release From Host Cell Virion Assembly Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Mitotic Metaphase Plate Congression Viral Life Cycle Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Endosome Organization Metaphase Plate Congression Endosomal Transport Protein Catabolic Process Regulation Of Centrosome Duplication Establishment Of Chromosome Localization Regulation Of Cell Division Regulation Of Centrosome Cycle Proteolysis Positive Regulation Of Exocytosis Positive Regulation Of Secretion Cellular Macromolecule Catabolic Process Negative Regulation Of Exosomal Secretion Memory T Cell Proliferation Positive Regulation Of Centriole Elongation Positive Regulation Of Viral Process Mitotic Sister Chromatid Segregation Membrane Budding Sister Chromatid Segregation Negative Regulation Of Cell Death Positive Regulation Of Centriole Replication Detection Of Hypoxia Endosome To Lysosome Transport Via Multivesicular Body Sorting Pathway Uterine Wall Breakdown Ovulation Cycle Process Vacuole Organization Protein Deubiquitination	Viral Budding Via Host ESCRT Complex Mitotic Metaphase Plate Congression Metaphase Plate Congression Viral Budding Establishment Of Chromosome Localization Cell Separation After Cytokinesis Mitotic Sister Chromatid Segregation Virion Assembly Sister Chromatid Segregation Regulation Of Mitotic Spindle Assembly Regulation Of Spindle Assembly Cell Division Regulation Of Mitotic Spindle Organization Endosomal Transport Vacuolar Transport Membrane Budding Chromosome Segregation Mitotic Nuclear Division Nucleus Organization Establishment Of Organelle Localization Mitotic Cell Cycle Process Negative Regulation Of Autophagic Vacuole Assembly Mitotic Cell Cycle Regulation Of Mitotic Cell Cycle Regulation Of Centrosome Duplication Organelle Localization Regulation Of Centrosome Cycle Vesicle-mediated Transport Viral Life Cycle Osteoblast Fate Commitment Regulation Of Cell Cycle Process Intracellular Transport Vesicle Organization Cell Cycle Process Posttranslational Protein Targeting To Membrane Positive Regulation Of Viral Release From Host Cell Regulation Of Cellular Component Organization Establishment Of Localization In Cell Negative Regulation Of Macroautophagy Establishment Of Protein Localization To Organelle Cell Cycle Regulation Of Autophagic Vacuole Assembly Protein Transport Regulation Of Mitotic Nuclear Division Establishment Of Protein Localization Regulation Of Vacuole Organization Membrane Organization Cellular Response To BMP Stimulus Regulation Of Microtubule Cytoskeleton Organization Regulation Of Cell Death
Tagcloud ?			degradative depletion dramatic eap30 egfrs endocytic endocytosed endosomal endosomes equally escrt golgi internalization intraluminal lysosomes m6prs machinery multivesicular mves recycling redistribution reflecting sorting stam tgn trafficking tsg101 vps22 vps24
Tagcloud (Difference) ?			degradative depletion dramatic eap30 egfrs endocytic endocytosed endosomal endosomes equally escrt golgi internalization intraluminal lysosomes m6prs machinery multivesicular mves recycling redistribution reflecting sorting stam tgn trafficking tsg101 vps22 vps24
Tagcloud (Intersection) ?