CHMP2A and USP54

Number of citations of the paper that reports this interaction (PMID 19302785)
6

Data Source:
BioGRID (pull down)

		CHMP2A	USP54
Gene Name		charged multivesicular body protein 2A	ubiquitin specific peptidase 54
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Membrane Late Endosome Membrane Extracellular Vesicular Exosome
	Molecular Function	Protein Binding Protein Domain Specific Binding	Protein Binding Ubiquitinyl Hydrolase Activity
	Biological Process	Cell Separation After Cytokinesis Nucleus Organization Vacuolar Transport Mitotic Metaphase Plate Congression Regulation Of Centrosome Duplication Protein Transport Viral Process Endosomal Transport Viral Life Cycle Viral Budding Via Host ESCRT Complex Establishment Of Protein Localization Regulation Of Viral Process Negative Regulation Of Cell Death Membrane Organization Regulation Of Mitotic Spindle Assembly Positive Regulation Of Viral Release From Host Cell Positive Regulation Of Exosomal Secretion Negative Regulation Of Centriole Elongation	Ubiquitin-dependent Protein Catabolic Process
Pathways		HIV Life Cycle Budding and maturation of HIV virion HIV Infection Endosomal Sorting Complex Required For Transport (ESCRT) Late Phase of HIV Life Cycle
Drugs
Diseases
GWAS
Protein-Protein Interactions		12 interactors: CHMP3 DOCK8 E2F4 EIF2B5 MITD1 NOL4 STAMBP TGFB3 USP54 USP8 VPS4A VPS4B	8 interactors: ATN1 ATXN1 CHMP1B CHMP2A CHMP2B CHMP4C EIF4E2 NXT2
Entrez ID		27243	159195
HPRD ID		12520	15641
Ensembl ID		ENSG00000130724	ENSG00000166348
Uniprot IDs		O43633	Q70EL1
PDB IDs
Enriched GO Terms of Interacting Partners?		Cell Separation After Cytokinesis Cell Division Cytokinesis Mitotic Cell Cycle Process Mitotic Cell Cycle Mitotic Cytokinesis Ubiquitin-independent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Cell Cycle Process Viral Budding Via Host ESCRT Complex Positive Regulation Of Viral Release From Host Cell Viral Budding Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Cell Cycle Regulation Of Viral Release From Host Cell Virion Assembly Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Mitotic Metaphase Plate Congression Viral Life Cycle Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Endosome Organization Metaphase Plate Congression Endosomal Transport Protein Catabolic Process Regulation Of Centrosome Duplication Establishment Of Chromosome Localization Regulation Of Cell Division Regulation Of Centrosome Cycle Proteolysis Positive Regulation Of Exocytosis Positive Regulation Of Secretion Cellular Macromolecule Catabolic Process Negative Regulation Of Exosomal Secretion Memory T Cell Proliferation Positive Regulation Of Centriole Elongation Positive Regulation Of Viral Process Mitotic Sister Chromatid Segregation Membrane Budding Sister Chromatid Segregation Negative Regulation Of Cell Death Positive Regulation Of Centriole Replication Detection Of Hypoxia Endosome To Lysosome Transport Via Multivesicular Body Sorting Pathway Uterine Wall Breakdown Ovulation Cycle Process Vacuole Organization Protein Deubiquitination	Regulation Of Mitotic Spindle Assembly Regulation Of Spindle Assembly Regulation Of Mitotic Spindle Organization Cell Separation After Cytokinesis Mitotic Metaphase Plate Congression Metaphase Plate Congression Regulation Of Centrosome Duplication Establishment Of Chromosome Localization Regulation Of Centrosome Cycle Vacuolar Transport Mitotic Sister Chromatid Segregation Sister Chromatid Segregation Nucleus Organization Regulation Of Mitotic Nuclear Division Regulation Of Microtubule Cytoskeleton Organization Regulation Of Microtubule-based Process Chromosome Segregation Regulation Of Cell Division Viral Budding Via Host ESCRT Complex Mitotic Nuclear Division Positive Regulation Of Viral Release From Host Cell Establishment Of Organelle Localization Regulation Of Protein Complex Assembly Viral Budding Regulation Of Mitotic Cell Cycle Organelle Localization Cell Division Regulation Of Cell Cycle Process Regulation Of Cytoskeleton Organization Regulation Of Viral Release From Host Cell Virion Assembly Viral Life Cycle Protein Transport Endosomal Transport Mitotic Cell Cycle Process Establishment Of Protein Localization Intracellular Transport Mitotic Cell Cycle Regulation Of Organelle Organization Regulation Of Cell Cycle Protein Localization Establishment Of Localization In Cell Chromosome Organization Cell Cycle Process Positive Regulation Of Viral Process Membrane Budding Negative Regulation Of Centriole Elongation Cellular Localization Cell Cycle Viral Process
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