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CHMP2A and EIF2B5
Number of citations of the paper that reports this interaction (PMID
16730941
)
46
Data Source:
HPRD
(two hybrid)
CHMP2A
EIF2B5
Gene Name
charged multivesicular body protein 2A
eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytosol
Membrane
Late Endosome Membrane
Extracellular Vesicular Exosome
Nucleus
Cytoplasm
Cytosol
Eukaryotic Translation Initiation Factor 2B Complex
Molecular Function
Protein Binding
Protein Domain Specific Binding
Translation Initiation Factor Activity
Guanyl-nucleotide Exchange Factor Activity
Protein Binding
Translation Initiation Factor Binding
Biological Process
Cell Separation After Cytokinesis
Nucleus Organization
Vacuolar Transport
Mitotic Metaphase Plate Congression
Regulation Of Centrosome Duplication
Protein Transport
Viral Process
Endosomal Transport
Viral Life Cycle
Viral Budding Via Host ESCRT Complex
Establishment Of Protein Localization
Regulation Of Viral Process
Negative Regulation Of Cell Death
Membrane Organization
Regulation Of Mitotic Spindle Assembly
Positive Regulation Of Viral Release From Host Cell
Positive Regulation Of Exosomal Secretion
Negative Regulation Of Centriole Elongation
Ovarian Follicle Development
Translation
Translational Initiation
Response To Heat
Response To Glucose
Gene Expression
Astrocyte Development
Oligodendrocyte Development
Negative Regulation Of Translational Initiation In Response To Stress
Response To Endoplasmic Reticulum Stress
Cellular Response To Drug
Myelination
Response To Peptide Hormone
Positive Regulation Of GTPase Activity
Cellular Protein Metabolic Process
Positive Regulation Of Translational Initiation
Astrocyte Differentiation
Pathways
HIV Life Cycle
Budding and maturation of HIV virion
HIV Infection
Endosomal Sorting Complex Required For Transport (ESCRT)
Late Phase of HIV Life Cycle
Recycling of eIF2:GDP
Translation
Eukaryotic Translation Initiation
Cap-dependent Translation Initiation
Drugs
Diseases
GWAS
Major depressive disorder (
22472876
)
Protein-Protein Interactions
12 interactors:
CHMP3
DOCK8
E2F4
EIF2B5
MITD1
NOL4
STAMBP
TGFB3
USP54
USP8
VPS4A
VPS4B
11 interactors:
APP
CHMP2A
CSNK1A1
CSNK2A1
CSNK2A2
EIF2B1
EIF2B2
EIF2B4
EIF2S2
GSK3A
GSK3B
Entrez ID
27243
8893
HPRD ID
12520
04898
Ensembl ID
ENSG00000130724
ENSG00000145191
Uniprot IDs
O43633
Q13144
PDB IDs
3JUI
Enriched GO Terms of Interacting Partners
?
Cell Separation After Cytokinesis
Cell Division
Cytokinesis
Mitotic Cell Cycle Process
Mitotic Cell Cycle
Mitotic Cytokinesis
Ubiquitin-independent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway
Cell Cycle Process
Viral Budding Via Host ESCRT Complex
Positive Regulation Of Viral Release From Host Cell
Viral Budding
Positive Regulation Of Exosomal Secretion
Regulation Of Exosomal Secretion
Cell Cycle
Regulation Of Viral Release From Host Cell
Virion Assembly
Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway
Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Mitotic Metaphase Plate Congression
Viral Life Cycle
Proteolysis Involved In Cellular Protein Catabolic Process
Cellular Protein Catabolic Process
Endosome Organization
Metaphase Plate Congression
Endosomal Transport
Protein Catabolic Process
Regulation Of Centrosome Duplication
Establishment Of Chromosome Localization
Regulation Of Cell Division
Regulation Of Centrosome Cycle
Proteolysis
Positive Regulation Of Exocytosis
Positive Regulation Of Secretion
Cellular Macromolecule Catabolic Process
Negative Regulation Of Exosomal Secretion
Memory T Cell Proliferation
Positive Regulation Of Centriole Elongation
Positive Regulation Of Viral Process
Mitotic Sister Chromatid Segregation
Membrane Budding
Sister Chromatid Segregation
Negative Regulation Of Cell Death
Positive Regulation Of Centriole Replication
Detection Of Hypoxia
Endosome To Lysosome Transport Via Multivesicular Body Sorting Pathway
Uterine Wall Breakdown
Ovulation Cycle Process
Vacuole Organization
Protein Deubiquitination
Wnt Signaling Pathway
Response To Heat
Negative Regulation Of Type B Pancreatic Cell Development
Regulation Of Cellular Protein Metabolic Process
Cellular Protein Metabolic Process
Negative Regulation Of Cellular Protein Metabolic Process
Regulation Of Protein Metabolic Process
Oligodendrocyte Development
Nervous System Development
Hypermethylation Of CpG Island
Negative Regulation Of Protein Metabolic Process
Response To Temperature Stimulus
Cellular Response To Interleukin-3
Neurogenesis
Negative Regulation Of Translational Initiation In Response To Stress
Positive Regulation Of Hydrolase Activity
Translational Initiation
Negative Regulation Of Glycogen (starch) Synthase Activity
Cell Development
Protein Metabolic Process
Regulation Of Translational Initiation
Regulation Of Translation
Negative Regulation Of Translation In Response To Stress
Oligodendrocyte Differentiation
System Development
Regulation Of Wnt Signaling Pathway
Rhythmic Process
Negative Regulation Of Cardiac Muscle Hypertrophy
Negative Regulation Of Cellular Metabolic Process
Protein Phosphorylation
Negative Regulation Of Glycogen Biosynthetic Process
Regulation Of Translational Initiation In Response To Stress
Negative Regulation Of Muscle Hypertrophy
Regulation Of Glycogen (starch) Synthase Activity
Glial Cell Development
Multicellular Organismal Development
Regulation Of Type B Pancreatic Cell Development
Regulation Of Protein Catabolic Process
Axon Guidance
Regulation Of Mitotic Nuclear Division
Positive Regulation Of Peptidyl-threonine Phosphorylation
Regulation Of Translation In Response To Stress
Regulation Of Catalytic Activity
Positive Regulation Of Catalytic Activity
Anatomical Structure Development
Regulation Of Mitotic Cell Cycle
Response To Glucose
Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Regulation Of Organelle Organization
Negative Regulation Of Translational Initiation
Tagcloud
?
1223t
3days
4months
584g
antenatal
ataxia
cach
cle
cree
deterioration
exome
hypomyelination
i408t
infantile
lethargy
leukoencephalopathy
optic
patch
poliovirus
r195h
resembling
resides
spasticity
vanishing
vomiting
vwm
Tagcloud (Difference)
?
1223t
3days
4months
584g
antenatal
ataxia
cach
cle
cree
deterioration
exome
hypomyelination
i408t
infantile
lethargy
leukoencephalopathy
optic
patch
poliovirus
r195h
resembling
resides
spasticity
vanishing
vomiting
vwm
Tagcloud (Intersection)
?