CHMP2A and TGFB3

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		CHMP2A	TGFB3
Gene Name		charged multivesicular body protein 2A	transforming growth factor, beta 3
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Membrane Late Endosome Membrane Extracellular Vesicular Exosome	Extracellular Region Extracellular Space Nucleus Plasma Membrane Cell Surface T-tubule Extracellular Matrix Platelet Alpha Granule Lumen Neuronal Cell Body
	Molecular Function	Protein Binding Protein Domain Specific Binding	Type II Transforming Growth Factor Beta Receptor Binding Cytokine Activity Protein Binding Growth Factor Activity Type I Transforming Growth Factor Beta Receptor Binding Type III Transforming Growth Factor Beta Receptor Binding Identical Protein Binding Protein Heterodimerization Activity Transforming Growth Factor Beta Binding
	Biological Process	Cell Separation After Cytokinesis Nucleus Organization Vacuolar Transport Mitotic Metaphase Plate Congression Regulation Of Centrosome Duplication Protein Transport Viral Process Endosomal Transport Viral Life Cycle Viral Budding Via Host ESCRT Complex Establishment Of Protein Localization Regulation Of Viral Process Negative Regulation Of Cell Death Membrane Organization Regulation Of Mitotic Spindle Assembly Positive Regulation Of Viral Release From Host Cell Positive Regulation Of Exosomal Secretion Negative Regulation Of Centriole Elongation	Activation Of MAPK Activity Response To Hypoxia In Utero Embryonic Development Platelet Degranulation Transforming Growth Factor Beta Receptor Signaling Pathway SMAD Protein Import Into Nucleus Salivary Gland Morphogenesis Female Pregnancy Aging Blood Coagulation Negative Regulation Of DNA Replication Negative Regulation Of Cell Proliferation Positive Regulation Of Epithelial To Mesenchymal Transition Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Negative Regulation Of Macrophage Cytokine Production Cell Growth Platelet Activation Extracellular Matrix Organization Positive Regulation Of Bone Mineralization Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Mammary Gland Development Response To Progesterone Positive Regulation Of Collagen Biosynthetic Process Response To Laminar Fluid Shear Stress Regulation Of Cell Proliferation Odontogenesis Uterine Wall Breakdown Regulation Of Apoptotic Process Positive Regulation Of Apoptotic Process Regulation Of MAPK Cascade Negative Regulation Of Neuron Apoptotic Process Response To Estrogen Ossification Involved In Bone Remodeling Cell-cell Junction Organization Positive Regulation Of DNA Replication Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Lung Alveolus Development Digestive Tract Development Embryonic Neurocranium Morphogenesis Inner Ear Development Positive Regulation Of Protein Secretion Positive Regulation Of Filopodium Assembly Positive Regulation Of Cell Division Palate Development Face Morphogenesis Frontal Suture Morphogenesis Positive Regulation Of SMAD Protein Import Into Nucleus SMAD Protein Signal Transduction Detection Of Hypoxia
Pathways		HIV Life Cycle Budding and maturation of HIV virion HIV Infection Endosomal Sorting Complex Required For Transport (ESCRT) Late Phase of HIV Life Cycle	Molecules associated with elastic fibres Elastic fibre formation Response to elevated platelet cytosolic Ca2+ ECM proteoglycans Platelet degranulation Platelet activation, signaling and aggregation
Drugs
Diseases
GWAS
Protein-Protein Interactions		12 interactors: CHMP3 DOCK8 E2F4 EIF2B5 MITD1 NOL4 STAMBP TGFB3 USP54 USP8 VPS4A VPS4B	13 interactors: ACVRL1 CCL20 CHMP2A CTGF ENG FMOD LTBP3 SDC4 TGFB2 TGFBR1 TGFBR2 TGFBR3 VASN
Entrez ID		27243	7043
HPRD ID		12520	01829
Ensembl ID		ENSG00000130724
Uniprot IDs		O43633	A5YM40 B3KVH9 P10600
PDB IDs			1KTZ 1TGJ 1TGK 2PJY 3EO1
Enriched GO Terms of Interacting Partners?		Cell Separation After Cytokinesis Cell Division Cytokinesis Mitotic Cell Cycle Process Mitotic Cell Cycle Mitotic Cytokinesis Ubiquitin-independent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Cell Cycle Process Viral Budding Via Host ESCRT Complex Positive Regulation Of Viral Release From Host Cell Viral Budding Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Cell Cycle Regulation Of Viral Release From Host Cell Virion Assembly Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Mitotic Metaphase Plate Congression Viral Life Cycle Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Endosome Organization Metaphase Plate Congression Endosomal Transport Protein Catabolic Process Regulation Of Centrosome Duplication Establishment Of Chromosome Localization Regulation Of Cell Division Regulation Of Centrosome Cycle Proteolysis Positive Regulation Of Exocytosis Positive Regulation Of Secretion Cellular Macromolecule Catabolic Process Negative Regulation Of Exosomal Secretion Memory T Cell Proliferation Positive Regulation Of Centriole Elongation Positive Regulation Of Viral Process Mitotic Sister Chromatid Segregation Membrane Budding Sister Chromatid Segregation Negative Regulation Of Cell Death Positive Regulation Of Centriole Replication Detection Of Hypoxia Endosome To Lysosome Transport Via Multivesicular Body Sorting Pathway Uterine Wall Breakdown Ovulation Cycle Process Vacuole Organization Protein Deubiquitination	Transforming Growth Factor Beta Receptor Signaling Pathway Cellular Response To Transforming Growth Factor Beta Stimulus Response To Transforming Growth Factor Beta Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Cellular Response To Growth Factor Stimulus Response To Growth Factor Pathway-restricted SMAD Protein Phosphorylation Enzyme Linked Receptor Protein Signaling Pathway Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Extracellular Matrix Organization Extracellular Structure Organization Regulation Of Cartilage Development Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Cellular Response To Growth Factor Stimulus Cellular Response To Organic Substance Blood Vessel Development Vasculature Development Negative Regulation Of Epithelial Cell Proliferation Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Angiogenesis Regulation Of Pathway-restricted SMAD Protein Phosphorylation Regulation Of Epithelial To Mesenchymal Transition Regulation Of Cellular Component Movement Response To Wounding Tube Development Regulation Of Cellular Response To Growth Factor Stimulus Positive Regulation Of Protein Phosphorylation Response To Organic Substance Regulation Of Chondrocyte Differentiation Blood Vessel Morphogenesis Positive Regulation Of Protein Metabolic Process Cell Migration Response To Lipid Positive Regulation Of Phosphorylation Cardiovascular System Development Cell Motility Positive Regulation Of Protein Modification Process Regulation Of Cell Proliferation Skeletal System Morphogenesis Skeletal System Development Extracellular Matrix Constituent Secretion Regulation Of Epithelial Cell Proliferation Organ Morphogenesis Regulation Of Cell Migration Regulation Of Cell Differentiation Cardiac Epithelial To Mesenchymal Transition Wound Healing Anatomical Structure Formation Involved In Morphogenesis Regulation Of Protein Phosphorylation
Tagcloud ?			alleles bcl3 cleft clefts conditional covariates d19s178 definitive disequilibrium ethnic incorporated incorporating lip modestly modifiers odds offspring parent permitting probands proto stratification tdt tgfa thra1 transforming transmission trios utilizing
Tagcloud (Difference) ?			alleles bcl3 cleft clefts conditional covariates d19s178 definitive disequilibrium ethnic incorporated incorporating lip modestly modifiers odds offspring parent permitting probands proto stratification tdt tgfa thra1 transforming transmission trios utilizing
Tagcloud (Intersection) ?