CHMP2A and STAMBP

Number of citations of the paper that reports this interaction (PMID 16760479)
38

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, two hybrid)

		CHMP2A	STAMBP
Gene Name		charged multivesicular body protein 2A	STAM binding protein
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Membrane Late Endosome Membrane Extracellular Vesicular Exosome	Nucleus Nucleoplasm Cytoplasm Early Endosome Plasma Membrane Cleavage Furrow Extracellular Vesicular Exosome
	Molecular Function	Protein Binding Protein Domain Specific Binding	Ubiquitin-specific Protease Activity Protein Binding Metallopeptidase Activity Metal Ion Binding
	Biological Process	Cell Separation After Cytokinesis Nucleus Organization Vacuolar Transport Mitotic Metaphase Plate Congression Regulation Of Centrosome Duplication Protein Transport Viral Process Endosomal Transport Viral Life Cycle Viral Budding Via Host ESCRT Complex Establishment Of Protein Localization Regulation Of Viral Process Negative Regulation Of Cell Death Membrane Organization Regulation Of Mitotic Spindle Assembly Positive Regulation Of Viral Release From Host Cell Positive Regulation Of Exosomal Secretion Negative Regulation Of Centriole Elongation	Mitotic Cytokinesis Proteolysis JAK-STAT Cascade Positive Regulation Of Cell Proliferation Negative Regulation Of Phosphatidylinositol 3-kinase Signaling Protein Deubiquitination Negative Regulation Of Neuron Apoptotic Process Negative Regulation Of Ras Protein Signal Transduction
Pathways		HIV Life Cycle Budding and maturation of HIV virion HIV Infection Endosomal Sorting Complex Required For Transport (ESCRT) Late Phase of HIV Life Cycle
Drugs
Diseases
GWAS
Protein-Protein Interactions		12 interactors: CHMP3 DOCK8 E2F4 EIF2B5 MITD1 NOL4 STAMBP TGFB3 USP54 USP8 VPS4A VPS4B	39 interactors: ALAS1 AMN BMPR1B CASR CHMP1A CHMP1B CHMP2A CHMP3 CHMP4A CHMP4B CHMP4C CHMP5 CLTC CTNNBL1 CYP2C9 EPS15 GRAP2 GRB2 ITGA5 MAP2K5 MAP3K2 NTPCR PJA1 RECQL5 RNF11 SMAD2 SMAD6 SMAD7 SPG7 STAM STAM2 TNFRSF1A TRAF6 TRIP13 UACA UBC UBE2S USP21 USP28
Entrez ID		27243	10617
HPRD ID		12520	05877
Ensembl ID		ENSG00000130724	ENSG00000124356
Uniprot IDs		O43633	O95630
PDB IDs			2XZE 3RZU 3RZV
Enriched GO Terms of Interacting Partners?		Cell Separation After Cytokinesis Cell Division Cytokinesis Mitotic Cell Cycle Process Mitotic Cell Cycle Mitotic Cytokinesis Ubiquitin-independent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Cell Cycle Process Viral Budding Via Host ESCRT Complex Positive Regulation Of Viral Release From Host Cell Viral Budding Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Cell Cycle Regulation Of Viral Release From Host Cell Virion Assembly Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Mitotic Metaphase Plate Congression Viral Life Cycle Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Endosome Organization Metaphase Plate Congression Endosomal Transport Protein Catabolic Process Regulation Of Centrosome Duplication Establishment Of Chromosome Localization Regulation Of Cell Division Regulation Of Centrosome Cycle Proteolysis Positive Regulation Of Exocytosis Positive Regulation Of Secretion Cellular Macromolecule Catabolic Process Negative Regulation Of Exosomal Secretion Memory T Cell Proliferation Positive Regulation Of Centriole Elongation Positive Regulation Of Viral Process Mitotic Sister Chromatid Segregation Membrane Budding Sister Chromatid Segregation Negative Regulation Of Cell Death Positive Regulation Of Centriole Replication Detection Of Hypoxia Endosome To Lysosome Transport Via Multivesicular Body Sorting Pathway Uterine Wall Breakdown Ovulation Cycle Process Vacuole Organization Protein Deubiquitination	Cell Separation After Cytokinesis Regulation Of Mitotic Spindle Assembly Regulation Of Spindle Assembly Mitotic Metaphase Plate Congression Regulation Of Mitotic Spindle Organization Metaphase Plate Congression Vacuolar Transport Regulation Of Centrosome Duplication Establishment Of Chromosome Localization Endosomal Transport Regulation Of Centrosome Cycle Mitotic Sister Chromatid Segregation Mitotic Nuclear Division Sister Chromatid Segregation Chromosome Segregation Positive Regulation Of Viral Release From Host Cell Nucleus Organization Cell Division Regulation Of Microtubule Cytoskeleton Organization Cell Cycle Process Intracellular Transport Membrane Organization Mitotic Cell Cycle Process Regulation Of Microtubule-based Process Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Viral Process Negative Regulation Of ERBB Signaling Pathway Protein Transport Mitotic Cell Cycle Viral Life Cycle Establishment Of Localization In Cell Establishment Of Protein Localization Regulation Of Mitotic Nuclear Division Regulation Of Protein Complex Assembly Regulation Of Viral Release From Host Cell Cellular Localization Virion Assembly Cell Cycle Enzyme Linked Receptor Protein Signaling Pathway Protein Localization Viral Budding Via Host ESCRT Complex Regulation Of Cellular Component Organization Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of ERBB Signaling Pathway Regulation Of Signaling Viral Budding Intracellular Signal Transduction Establishment Of Organelle Localization Regulation Of Cell Cycle Process Regulation Of Cytoskeleton Organization
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