DISC1 and XRN2

  • Number of citations of the paper that reports this interaction (PubMedID 17043677)
  • 96
  • Data Source:
  • BioGRID (two hybrid)

DISC1

XRN2

Description disrupted in schizophrenia 1 5-3 exoribonuclease 2
Image No pdb structure No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alzheimer's disease ( 19118814)
  • Amyotrophic lateral sclerosis ( 19451621)
  • Neuranatomic and neurocognitive phenotypes ( 21483430)
  • Response to antineoplastic agents ( 21659360)
  • Response to statin therapy ( 20339536)
Interacting Genes 113 interacting genes: ACTG1 ACTN2 AGTPBP1 AKAP6 AKAP9 ARIH2 ATF4 ATF5 ATF7IP BICD1 BZRAP1 C14orf166 CCDC136 CCDC141 CCDC24 CCDC88A CDC5L CDK5RAP3 CEP170 CEP57L1 CEP63 CIT CLU COL4A1 DCTN1 DCTN2 DMD DNAJC7 DPYSL2 DPYSL3 DST DYNC1H1 EEF2 EIF3H EXOC1 EXOC4 EXOC7 FBXO41 FEZ1 FRYL GNB1 GNPTAB GPRASP2 HERC2P2 IFT20 IMMT ITSN1 KALRN KANSL1 KCNQ5 KIAA1377 KIF3A KIF3C KIFAP3 MACF1 MAP1A MATR3 MEMO1 MLLT10 MPPED1 MVP MYO1A MYT1L NDE1 NDEL1 NEFM NUP160 OLFM1 PAFAH1B1 PCNT PCNXL4 PDE4B PGK1 PPM1E PPP4R1 PPP5C RABGAP1 RAD21 RANBP9 RASSF7 RBSN ROGDI SH3BP5 SMARCE1 SMC2 SMC3 SNX6 SPARCL1 SPTAN1 SPTBN1 SPTBN4 SRGAP2 SRGAP3 STX18 SYBU SYNE1 TFIP11 TIAM2 TNIK TNKS TRAF3IP1 TRIO TUBB TUBB2A UTRN XPNPEP1 XRN2 YWHAE YWHAG YWHAQ YWHAZ ZNF197 ZNF365 24 interacting genes: ALDH1B1 ATRN COMT CSNK2A1 CTSC DISC1 DXO EEF1A1 EIF3L EIF5A EIF6 ERG EXOSC10 EXOSC8 LSM3 MOCS3 MRPL4 MRPS10 PRAME PSMA3 TARDBP TIPARP TOLLIP UPF2
Entrez ID 27185 22803
HPRD ID 05553 10309
Ensembl ID ENSG00000162946 ENSG00000088930
Uniprot IDs C4P094 C4P096 C4P098 C4P0A4 C4P0A5 C4P0C4 C4P0C8 C4P0D0 C4P0D1 C4P0D2 C4P0D3 Q9NRI5 Q9H0D6
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?
accelerate  aggregated  allosteric  amplify  appropriated  assemblies  assembly  biochemically  capsid  catalytically  collections  commonality  conceptualized  continuum  crowded  exploit  governed  labile  machines  multimers  multiprotein  pathologically  prions  replicating  replicative  reprogrammed  reset  suited  transmissibility 
8s  arabidopsis  at1g52930  at3g15460  atbrx1  biogenesis  brx1  bypassed  ets  eukaryotes  export  implying  intermediates  its1  leaves  nucleolus  orthologs  plant  pointed  processing  rbfs  ribosomal  ribosome  rrna  spacer  steps  thaliana  transcribed  ubiquitously 
Tagcloud (Difference) ?
accelerate  aggregated  allosteric  amplify  appropriated  assemblies  assembly  biochemically  capsid  catalytically  collections  commonality  conceptualized  continuum  crowded  exploit  governed  labile  machines  multimers  multiprotein  pathologically  prions  replicating  replicative  reprogrammed  reset  suited  transmissibility 
8s  arabidopsis  at1g52930  at3g15460  atbrx1  biogenesis  brx1  bypassed  ets  eukaryotes  export  implying  intermediates  its1  leaves  nucleolus  orthologs  plant  pointed  processing  rbfs  ribosomal  ribosome  rrna  spacer  steps  thaliana  transcribed  ubiquitously 
Tagcloud (Intersection) ?