DISC1 and SPTAN1

  • Number of citations of the paper that reports this interaction (PubMedID 17043677)
  • 96
  • Data Source:
  • BioGRID (two hybrid)

DISC1

SPTAN1

Description disrupted in schizophrenia 1 spectrin, alpha, non-erythrocytic 1
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alzheimer's disease ( 19118814)
  • Amyotrophic lateral sclerosis ( 19451621)
  • Neuranatomic and neurocognitive phenotypes ( 21483430)
  • Response to antineoplastic agents ( 21659360)
  • Response to statin therapy ( 20339536)
Interacting Genes 113 interacting genes: ACTG1 ACTN2 AGTPBP1 AKAP6 AKAP9 ARIH2 ATF4 ATF5 ATF7IP BICD1 BZRAP1 C14orf166 CCDC136 CCDC141 CCDC24 CCDC88A CDC5L CDK5RAP3 CEP170 CEP57L1 CEP63 CIT CLU COL4A1 DCTN1 DCTN2 DMD DNAJC7 DPYSL2 DPYSL3 DST DYNC1H1 EEF2 EIF3H EXOC1 EXOC4 EXOC7 FBXO41 FEZ1 FRYL GNB1 GNPTAB GPRASP2 HERC2P2 IFT20 IMMT ITSN1 KALRN KANSL1 KCNQ5 KIAA1377 KIF3A KIF3C KIFAP3 MACF1 MAP1A MATR3 MEMO1 MLLT10 MPPED1 MVP MYO1A MYT1L NDE1 NDEL1 NEFM NUP160 OLFM1 PAFAH1B1 PCNT PCNXL4 PDE4B PGK1 PPM1E PPP4R1 PPP5C RABGAP1 RAD21 RANBP9 RASSF7 RBSN ROGDI SH3BP5 SMARCE1 SMC2 SMC3 SNX6 SPARCL1 SPTAN1 SPTBN1 SPTBN4 SRGAP2 SRGAP3 STX18 SYBU SYNE1 TFIP11 TIAM2 TNIK TNKS TRAF3IP1 TRIO TUBB TUBB2A UTRN XPNPEP1 XRN2 YWHAE YWHAG YWHAQ YWHAZ ZNF197 ZNF365 48 interacting genes: ABI1 ABL1 ACP1 ACTA1 ACTB ADD1 ANK1 CAPN1 CASP3 CASP7 CEP63 CTNNA1 DDX24 DES DISC1 EPB41 EPB41L2 EPB42 ERCC4 EVL EXOC1 FANCA FANCC GAP43 GRIA2 GRIN1 GRIN2A GRIN2B GRIN2D MAPK6 NEFL PIN4 PLEC PLEKHA5 PRKCB PTOV1 SHANK1 SHANK3 SLC9A2 SOS1 SPTB SPTBN1 SRC STAT1 SYN1 TANC1 TES TSSC4
Entrez ID 27185 6709
HPRD ID 05553 01684
Ensembl ID ENSG00000162946 ENSG00000197694
Uniprot IDs C4P094 C4P096 C4P098 C4P0A4 C4P0A5 C4P0C4 C4P0C8 C4P0D0 C4P0D1 C4P0D2 C4P0D3 Q9NRI5 Q13813
PDB IDs 2FOT 3F31 3FB2
Enriched GO Terms of Interacting Partners?
Tagcloud ?
accelerate  aggregated  allosteric  amplify  appropriated  assemblies  assembly  biochemically  capsid  catalytically  collections  commonality  conceptualized  continuum  crowded  exploit  governed  labile  machines  multimers  multiprotein  pathologically  prions  replicating  replicative  reprogrammed  reset  suited  transmissibility 
adenocarcinomas  atxn2  biology  consistently  couple  deregulation  dhx9  driver  exome  hundreds  kras  mutations  myof  never  overlap  preferentially  ptpn13  recurrent  respective  rps6kb2  seq  sequenced  smokers  somatic  sp1  stratification  targetable  ten  thousands 
Tagcloud (Difference) ?
accelerate  aggregated  allosteric  amplify  appropriated  assemblies  assembly  biochemically  capsid  catalytically  collections  commonality  conceptualized  continuum  crowded  exploit  governed  labile  machines  multimers  multiprotein  pathologically  prions  replicating  replicative  reprogrammed  reset  suited  transmissibility 
adenocarcinomas  atxn2  biology  consistently  couple  deregulation  dhx9  driver  exome  hundreds  kras  mutations  myof  never  overlap  preferentially  ptpn13  recurrent  respective  rps6kb2  seq  sequenced  smokers  somatic  sp1  stratification  targetable  ten  thousands 
Tagcloud (Intersection) ?