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XRN2
Gene Name
5-3 exoribonuclease 2
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleolus
Membrane
Aggresome
Molecular Function
Transcription Termination Site Sequence-specific DNA Binding
Nuclease Activity
5'-3' Exoribonuclease Activity
Zinc Ion Binding
5'-3' Exonuclease Activity
Poly(A) RNA Binding
Biological Process
DNA Catabolic Process, Exonucleolytic
DNA-templated Transcription, Termination
Regulation Of Transcription, DNA-templated
RNA Processing
MRNA Processing
RNA Catabolic Process
Spermatogenesis
Cell Growth
RNA Metabolic Process
RNA Phosphodiester Bond Hydrolysis, Exonucleolytic
Pathways
Protein folding
Chaperonin-mediated protein folding
Association of TriC/CCT with target proteins during biosynthesis
Drugs
Diseases
GWAS
Protein-protein Interactions
24 interactors:
ALDH1B1
ATRN
COMT
CSNK2A1
CTSC
DISC1
DXO
EEF1A1
EIF3L
EIF5A
EIF6
ERG
EXOSC10
EXOSC8
LSM3
MOCS3
MRPL4
MRPS10
PRAME
PSMA3
TARDBP
TIPARP
TOLLIP
UPF2
Entrez ID
22803
HPRD ID
10309
Ensembl ID
ENSG00000088930
Uniprot IDs
Q9H0D6
PDB IDs
Enriched GO Terms of Interacting Partners
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Gene Expression
Nuclear-transcribed MRNA Catabolic Process
MRNA Catabolic Process
RNA Catabolic Process
Positive Regulation Of Protein Catabolic Process
Aromatic Compound Catabolic Process
MRNA Metabolic Process
Nuclear MRNA Surveillance
Translational Elongation
RNA Surveillance
Catabolic Process
Regulation Of Protein Catabolic Process
Translation
Cellular Metabolic Process
Translational Initiation
RNA Metabolic Process
Positive Regulation Of Protein Metabolic Process
Cellular Macromolecule Catabolic Process
Nitrogen Compound Metabolic Process
Biosynthetic Process
Nuclear Export
Ribonucleoprotein Complex Biogenesis
Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay
Cellular Macromolecule Biosynthetic Process
Metabolic Process
Estrogen Metabolic Process
Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic
Macromolecule Biosynthetic Process
Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process
RNA Localization
Positive Regulation Of Cellular Protein Catabolic Process
Positive Regulation Of Wnt Signaling Pathway
Ribosome Biogenesis
Regulation Of Protein Metabolic Process
Cellular Aromatic Compound Metabolic Process
Posttranscriptional Regulation Of Gene Expression
Positive Regulation Of Homocysteine Metabolic Process
TRNA Wobble Position Uridine Thiolation
Enzyme Active Site Formation Via L-cysteine Persulfide
Cellular Response To Phosphate Starvation
Negative Regulation Of Potassium Ion Export
Nuclear Retention Of Unspliced Pre-mRNA At The Site Of Transcription
Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay
Cellular Nitrogen Compound Metabolic Process
Regulation Of Metabolic Process
Regulation Of RNA Stability
Cellular Protein Metabolic Process
Regulation Of Homocysteine Metabolic Process
Protein Adenylylation
Regulation Of Heart Rate By Hormone
Tagcloud
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8s
arabidopsis
at1g52930
at3g15460
atbrx1
biogenesis
brx1
bypassed
ets
eukaryotes
export
implying
intermediates
its1
leaves
nucleolus
orthologs
plant
pointed
processing
rbfs
ribosomal
ribosome
rrna
spacer
steps
thaliana
transcribed
ubiquitously