GEM and PDLIM7

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
HPRD (two hybrid)

		GEM	PDLIM7
Gene Name		GTP binding protein overexpressed in skeletal muscle	PDZ and LIM domain 7 (enigma)
Image
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasmic Side Of Plasma Membrane Midbody Spindle Midzone Mitotic Spindle	Stress Fiber Ruffle Nucleus Cytoplasm Focal Adhesion Actin Cytoskeleton
	Molecular Function	Magnesium Ion Binding GTPase Activity Protein Binding Calmodulin Binding GTP Binding GDP Binding	Protein Binding Zinc Ion Binding
	Biological Process	Immune Response Mitotic Nuclear Division Signal Transduction Cell Surface Receptor Signaling Pathway Small GTPase Mediated Signal Transduction Chromosome Organization Metaphase Plate Congression	Ossification Receptor-mediated Endocytosis Multicellular Organismal Development Actin Cytoskeleton Organization Cell Differentiation Positive Regulation Of Osteoblast Differentiation
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		40 interactors: A2M AHCYL1 APOH BLZF1 BMP1 CCDC102B CCDC67 CLDN15 CLEC4G COG8 CTSL GMIP GOLGA2 IKZF3 INO80E KCTD9 KLC3 KRT31 KRT40 KRTAP10-3 KRTAP10-7 LZTS2 NDUFAF3 NDUFS8 NOTCH2NL PDLIM7 PNMA1 RNF7 RUNDC3A SDHB SSX2IP TCF4 TFIP11 TRAF1 TRIM23 TRIM27 TRIM54 VTN YBEY YWHAB	34 interactors: AP5B1 BSG C20orf195 CCDC185 DGCR6 ENKD1 GEM GFAP HNRNPD IQGAP1 MDM2 PAK7 PCBP1 PHF1 PRKCA PRKCB PRKCZ PRKD2 PSMF1 RET SH2B2 SH3BP2 SMURF1 SPP1 TP53 TPM2 TRAF2 TRAF3 TSG101 UBE2I UBQLN4 WWP2 ZMYND11 ZNF165
Entrez ID		2669	9260
HPRD ID		11553	10436
Ensembl ID		ENSG00000164949	ENSG00000196923
Uniprot IDs		P55040	Q9NR12
PDB IDs		2CJW 2G3Y 2HT6	2Q3G
Enriched GO Terms of Interacting Partners?		Cellular Component Assembly Mitochondrial Respiratory Chain Complex I Assembly Mitochondrial Respiratory Chain Complex I Biogenesis Blood Coagulation, Intrinsic Pathway Extracellular Matrix Disassembly Protein Complex Assembly Mitochondrial Respiratory Chain Complex Assembly Regulation Of Complement Activation Intracellular Transport Regulation Of Protein Binding Spliceosomal Complex Disassembly Establishment Of Localization In Cell Small GTPase Mediated Signal Transduction Extracellular Matrix Organization Extracellular Structure Organization	Regulation Of Signaling Regulation Of Signal Transduction Positive Regulation Of Cellular Protein Metabolic Process Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Intracellular Signal Transduction Positive Regulation Of Protein Metabolic Process Positive Regulation Of Signal Transduction Cell Death Death Response To Organic Substance Immune System Process Regulation Of Protein Metabolic Process Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cellular Response To Organic Substance Histone H3-T6 Phosphorylation Apoptotic Process Regulation Of Cellular Protein Metabolic Process Programmed Cell Death Regulation Of Nitrogen Compound Metabolic Process Viral Process Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Protein Ubiquitination Regulation Of Metabolic Process Negative Regulation Of Signal Transduction Positive Regulation Of Cell Adhesion Cellular Response To Growth Factor Stimulus Regulation Of Apoptotic Process Protein Modification By Small Protein Conjugation Vascular Endothelial Growth Factor Receptor Signaling Pathway Response To Growth Factor Protein Catabolic Process Cell Surface Receptor Signaling Pathway Negative Regulation Of Signaling Positive Regulation Of Protein Modification Process Negative Regulation Of Apoptotic Process Positive Regulation Of NF-kappaB Transcription Factor Activity Regulation Of Cell Death Blood Coagulation Cellular Protein Modification Process Negative Regulation Of Programmed Cell Death Hemostasis Regulation Of Cellular Process Regulation Of Establishment Of Protein Localization Cellular Response To Stimulus Regulation Of Transcription, DNA-templated Negative Regulation Of Insulin Receptor Signaling Pathway Mitotic Cell Cycle Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process
Tagcloud ?		annotation centralized clinvar coherent compilation consortium curates curation das elect empowering exome expandable freestanding gbrowse guid https informs interrogation lsdb mseqdr mtdna phenotyping prioritize secure shareholders suite tracks void
Tagcloud (Difference) ?		annotation centralized clinvar coherent compilation consortium curates curation das elect empowering exome expandable freestanding gbrowse guid https informs interrogation lsdb mseqdr mtdna phenotyping prioritize secure shareholders suite tracks void
Tagcloud (Intersection) ?