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PDLIM7 and PRKD2
Number of citations of the paper that reports this interaction (PMID
15231748
)
65
Data Source:
BioGRID
(two hybrid)
PDLIM7
PRKD2
Gene Name
PDZ and LIM domain 7 (enigma)
protein kinase D2
Image
Gene Ontology Annotations
Cellular Component
Stress Fiber
Ruffle
Nucleus
Cytoplasm
Focal Adhesion
Actin Cytoskeleton
Nucleus
Nucleoplasm
Cytoplasm
Golgi Apparatus
Plasma Membrane
Molecular Function
Protein Binding
Zinc Ion Binding
Protein Kinase Activity
Protein Serine/threonine Kinase Activity
Protein Kinase C Activity
Protein Binding
ATP Binding
Metal Ion Binding
Biological Process
Ossification
Receptor-mediated Endocytosis
Multicellular Organismal Development
Actin Cytoskeleton Organization
Cell Differentiation
Positive Regulation Of Osteoblast Differentiation
Angiogenesis
Positive Regulation Of Endothelial Cell Proliferation
Protein Phosphorylation
Cell Adhesion
Cell Death
Positive Regulation Of Endothelial Cell Migration
Peptidyl-serine Phosphorylation
Positive Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway
Positive Regulation Of Interleukin-2 Production
Positive Regulation Of Interleukin-8 Production
Positive Regulation Of CREB Transcription Factor Activity
Positive Regulation Of Peptidyl-serine Phosphorylation
Intracellular Signal Transduction
Cellular Response To Vascular Endothelial Growth Factor Stimulus
Positive Regulation Of Endothelial Cell Chemotaxis By VEGF-activated Vascular Endothelial Growth Factor Receptor Signaling Pathway
Positive Regulation Of Blood Vessel Endothelial Cell Migration
Positive Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway
Positive Regulation Of Angiogenesis
Positive Regulation Of Cell Adhesion
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Protein Autophosphorylation
Vascular Endothelial Growth Factor Receptor Signaling Pathway
T Cell Receptor Signaling Pathway
Positive Regulation Of T Cell Receptor Signaling Pathway
Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Positive Regulation Of NF-kappaB Transcription Factor Activity
Endothelial Tube Morphogenesis
Positive Regulation Of ERK1 And ERK2 Cascade
Protein Kinase D Signaling
Positive Regulation Of Histone Deacetylase Activity
Positive Regulation Of Intracellular Signal Transduction
Positive Regulation Of DNA Biosynthetic Process
Positive Regulation Of Endothelial Cell Chemotaxis
Pathways
Drugs
Diseases
GWAS
Chronic lymphocytic leukemia (
18758461
)
Protein-Protein Interactions
34 interactors:
AP5B1
BSG
C20orf195
CCDC185
DGCR6
ENKD1
GEM
GFAP
HNRNPD
IQGAP1
MDM2
PAK7
PCBP1
PHF1
PRKCA
PRKCB
PRKCZ
PRKD2
PSMF1
RET
SH2B2
SH3BP2
SMURF1
SPP1
TP53
TPM2
TRAF2
TRAF3
TSG101
UBE2I
UBQLN4
WWP2
ZMYND11
ZNF165
17 interactors:
CASK
DST
GLRX3
GORASP1
GRIP1
HDAC7
HEY1
IFNAR1
MTF2
PDLIM7
PFDN1
PSG3
RARB
RRBP1
RXRA
SNRNP70
TGOLN2
Entrez ID
9260
25865
HPRD ID
10436
09523
Ensembl ID
ENSG00000196923
ENSG00000105287
Uniprot IDs
Q9NR12
M0QZW1
M0R2R2
Q8NCK8
Q9BZL6
PDB IDs
2Q3G
2COA
3BGM
Enriched GO Terms of Interacting Partners
?
Regulation Of Signaling
Regulation Of Signal Transduction
Positive Regulation Of Cellular Protein Metabolic Process
Enzyme Linked Receptor Protein Signaling Pathway
Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Intracellular Signal Transduction
Positive Regulation Of Protein Metabolic Process
Positive Regulation Of Signal Transduction
Cell Death
Death
Response To Organic Substance
Immune System Process
Regulation Of Protein Metabolic Process
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Cellular Response To Organic Substance
Histone H3-T6 Phosphorylation
Apoptotic Process
Regulation Of Cellular Protein Metabolic Process
Programmed Cell Death
Regulation Of Nitrogen Compound Metabolic Process
Viral Process
Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Protein Ubiquitination
Regulation Of Metabolic Process
Negative Regulation Of Signal Transduction
Positive Regulation Of Cell Adhesion
Cellular Response To Growth Factor Stimulus
Regulation Of Apoptotic Process
Protein Modification By Small Protein Conjugation
Vascular Endothelial Growth Factor Receptor Signaling Pathway
Response To Growth Factor
Protein Catabolic Process
Cell Surface Receptor Signaling Pathway
Negative Regulation Of Signaling
Positive Regulation Of Protein Modification Process
Negative Regulation Of Apoptotic Process
Positive Regulation Of NF-kappaB Transcription Factor Activity
Regulation Of Cell Death
Blood Coagulation
Cellular Protein Modification Process
Negative Regulation Of Programmed Cell Death
Hemostasis
Regulation Of Cellular Process
Regulation Of Establishment Of Protein Localization
Cellular Response To Stimulus
Regulation Of Transcription, DNA-templated
Negative Regulation Of Insulin Receptor Signaling Pathway
Mitotic Cell Cycle Process
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Positive Regulation Of Gene Expression
Regulation Of Osteoblast Differentiation
Cell Differentiation
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Cardiac Chamber Development
Developmental Process
Positive Regulation Of Transcription, DNA-templated
Retinoic Acid Receptor Signaling Pathway
Ventricular Cardiac Muscle Cell Differentiation
Cellular Response To Steroid Hormone Stimulus
Multicellular Organismal Development
Cardiac Muscle Tissue Development
Positive Regulation Of Macromolecule Biosynthetic Process
Regulation Of Ossification
Intracellular Receptor Signaling Pathway
Heart Development
Regulation Of Cell Differentiation
Positive Regulation Of Cellular Biosynthetic Process
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Heart Morphogenesis
Ventricular Cardiac Muscle Tissue Morphogenesis
Glandular Epithelial Cell Differentiation
Cellular Response To Hormone Stimulus
Negative Regulation Of Transcription, DNA-templated
Ventricular Cardiac Muscle Tissue Development
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Cardiac Muscle Tissue Morphogenesis
Cardiac Septum Morphogenesis
Positive Regulation Of Cellular Metabolic Process
Regulation Of Transcription From RNA Polymerase II Promoter
Ossification
Regulation Of RNA Metabolic Process
Muscle Tissue Morphogenesis
Muscle Organ Morphogenesis
Cardiac Ventricle Morphogenesis
Positive Regulation Of Osteoblast Differentiation
Striated Muscle Tissue Development
Negative Regulation Of Cell Differentiation
Muscle Cell Differentiation
Negative Regulation Of Gene Expression
Muscle Tissue Development
Negative Regulation Of Biosynthetic Process
Positive Regulation Of Translational Initiation By Iron
Cardiac Septum Development
Regulation Of Gene Expression
Anatomical Structure Development
Regulation Of Nitrogen Compound Metabolic Process
Vasculogenesis
Positive Regulation Of Ossification
Tagcloud
?
a172
cdk2
crt0066101
dismal
e2f1
gbm
gbm2
gli25
glioblastoma
glioma
gliomagenesis
gm133
hallmarks
hypophosphorylation
mer
multiforme
mut
p15
pkb
pkc
prb
profoundly
retinoblastoma
senescence
silencing
t98g
u251
u87mg
Tagcloud (Difference)
?
a172
cdk2
crt0066101
dismal
e2f1
gbm
gbm2
gli25
glioblastoma
glioma
gliomagenesis
gm133
hallmarks
hypophosphorylation
mer
multiforme
mut
p15
pkb
pkc
prb
profoundly
retinoblastoma
senescence
silencing
t98g
u251
u87mg
Tagcloud (Intersection)
?