GEM and NDUFS8

Number of citations of the paper that reports this interaction (PMID 18624398)
4

Data Source:
BioGRID (two hybrid)

		GEM	NDUFS8
Gene Name		GTP binding protein overexpressed in skeletal muscle	NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasmic Side Of Plasma Membrane Midbody Spindle Midzone Mitotic Spindle	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Respiratory Chain Complex I
	Molecular Function	Magnesium Ion Binding GTPase Activity Protein Binding Calmodulin Binding GTP Binding GDP Binding	NADH Dehydrogenase Activity NADH Dehydrogenase (ubiquinone) Activity Metal Ion Binding 4 Iron, 4 Sulfur Cluster Binding
	Biological Process	Immune Response Mitotic Nuclear Division Signal Transduction Cell Surface Receptor Signaling Pathway Small GTPase Mediated Signal Transduction Chromosome Organization Metaphase Plate Congression	Mitochondrial Electron Transport, NADH To Ubiquinone Response To Oxidative Stress Respiratory Electron Transport Chain Mitochondrial Respiratory Chain Complex I Assembly Cellular Metabolic Process Small Molecule Metabolic Process
Pathways			Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. Respiratory electron transport The citric acid (TCA) cycle and respiratory electron transport
Drugs			NADH
Diseases
GWAS
Protein-Protein Interactions		40 interactors: A2M AHCYL1 APOH BLZF1 BMP1 CCDC102B CCDC67 CLDN15 CLEC4G COG8 CTSL GMIP GOLGA2 IKZF3 INO80E KCTD9 KLC3 KRT31 KRT40 KRTAP10-3 KRTAP10-7 LZTS2 NDUFAF3 NDUFS8 NOTCH2NL PDLIM7 PNMA1 RNF7 RUNDC3A SDHB SSX2IP TCF4 TFIP11 TRAF1 TRIM23 TRIM27 TRIM54 VTN YBEY YWHAB	1 interactors: GEM
Entrez ID		2669	4728
HPRD ID		11553	03683
Ensembl ID		ENSG00000164949	ENSG00000110717
Uniprot IDs		P55040	O00217
PDB IDs		2CJW 2G3Y 2HT6
Enriched GO Terms of Interacting Partners?		Cellular Component Assembly Mitochondrial Respiratory Chain Complex I Assembly Mitochondrial Respiratory Chain Complex I Biogenesis Blood Coagulation, Intrinsic Pathway Extracellular Matrix Disassembly Protein Complex Assembly Mitochondrial Respiratory Chain Complex Assembly Regulation Of Complement Activation Intracellular Transport Regulation Of Protein Binding Spliceosomal Complex Disassembly Establishment Of Localization In Cell Small GTPase Mediated Signal Transduction Extracellular Matrix Organization Extracellular Structure Organization	Metaphase Plate Congression Establishment Of Chromosome Localization
Tagcloud ?		annotation centralized clinvar coherent compilation consortium curates curation das elect empowering exome expandable freestanding gbrowse guid https informs interrogation lsdb mseqdr mtdna phenotyping prioritize secure shareholders suite tracks void	adar ard1 cct3 cd48 csrp2 d9sva dedifferentiation develops distinction gbap grades hccs il7r lama3 md moderately neighborhood nin nodule occasionally plgl ppib predictability psmd4 rdbp sequentially tle1 wd wds
Tagcloud (Difference) ?		annotation centralized clinvar coherent compilation consortium curates curation das elect empowering exome expandable freestanding gbrowse guid https informs interrogation lsdb mseqdr mtdna phenotyping prioritize secure shareholders suite tracks void	adar ard1 cct3 cd48 csrp2 d9sva dedifferentiation develops distinction gbap grades hccs il7r lama3 md moderately neighborhood nin nodule occasionally plgl ppib predictability psmd4 rdbp sequentially tle1 wd wds
Tagcloud (Intersection) ?