PDLIM7 and C20orf195

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		PDLIM7	C20orf195
Gene Name		PDZ and LIM domain 7 (enigma)	chromosome 20 open reading frame 195
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Stress Fiber Ruffle Nucleus Cytoplasm Focal Adhesion Actin Cytoskeleton	Extracellular Vesicular Exosome
	Molecular Function	Protein Binding Zinc Ion Binding
	Biological Process	Ossification Receptor-mediated Endocytosis Multicellular Organismal Development Actin Cytoskeleton Organization Cell Differentiation Positive Regulation Of Osteoblast Differentiation
Pathways
Drugs
Diseases
GWAS			Prostate cancer ( 23535732)
Protein-Protein Interactions		34 interactors: AP5B1 BSG C20orf195 CCDC185 DGCR6 ENKD1 GEM GFAP HNRNPD IQGAP1 MDM2 PAK7 PCBP1 PHF1 PRKCA PRKCB PRKCZ PRKD2 PSMF1 RET SH2B2 SH3BP2 SMURF1 SPP1 TP53 TPM2 TRAF2 TRAF3 TSG101 UBE2I UBQLN4 WWP2 ZMYND11 ZNF165	20 interactors: CALCOCO2 CCDC102B CCDC85B CDA FAM9B GOLGA2 GPBP1 HMBOX1 KRT40 LZTS2 MAGEA12 MDFI MGAT5B MTUS2 PDLIM7 RBPMS REL SSSCA1 SSX2IP TRIM27
Entrez ID		9260	79025
HPRD ID		10436	14682
Ensembl ID		ENSG00000196923	ENSG00000125531
Uniprot IDs		Q9NR12	Q9BVV2
PDB IDs		2Q3G
Enriched GO Terms of Interacting Partners?		Regulation Of Signaling Regulation Of Signal Transduction Positive Regulation Of Cellular Protein Metabolic Process Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Intracellular Signal Transduction Positive Regulation Of Protein Metabolic Process Positive Regulation Of Signal Transduction Cell Death Death Response To Organic Substance Immune System Process Regulation Of Protein Metabolic Process Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cellular Response To Organic Substance Histone H3-T6 Phosphorylation Apoptotic Process Regulation Of Cellular Protein Metabolic Process Programmed Cell Death Regulation Of Nitrogen Compound Metabolic Process Viral Process Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Protein Ubiquitination Regulation Of Metabolic Process Negative Regulation Of Signal Transduction Positive Regulation Of Cell Adhesion Cellular Response To Growth Factor Stimulus Regulation Of Apoptotic Process Protein Modification By Small Protein Conjugation Vascular Endothelial Growth Factor Receptor Signaling Pathway Response To Growth Factor Protein Catabolic Process Cell Surface Receptor Signaling Pathway Negative Regulation Of Signaling Positive Regulation Of Protein Modification Process Negative Regulation Of Apoptotic Process Positive Regulation Of NF-kappaB Transcription Factor Activity Regulation Of Cell Death Blood Coagulation Cellular Protein Modification Process Negative Regulation Of Programmed Cell Death Hemostasis Regulation Of Cellular Process Regulation Of Establishment Of Protein Localization Cellular Response To Stimulus Regulation Of Transcription, DNA-templated Negative Regulation Of Insulin Receptor Signaling Pathway Mitotic Cell Cycle Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process	Regulation Of Protein Localization To Nucleus Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Gene Expression Negative Regulation Of Protein Localization To Nucleus Negative Regulation Of Interleukin-2 Secretion Negative Regulation Of Biosynthetic Process Regulation Of Protein Localization Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Binding Transcription, DNA-templated RNA Biosynthetic Process Cytosine Metabolic Process Cytokine Production Negative Regulation Of Calcium Ion Import Intraciliary Transport Involved In Cilium Morphogenesis Regulation Of Cellular Localization
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