PDLIM7 and BSG

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		PDLIM7	BSG
Gene Name		PDZ and LIM domain 7 (enigma)	basigin (Ok blood group)
Image
Gene Ontology Annotations	Cellular Component	Stress Fiber Ruffle Nucleus Cytoplasm Focal Adhesion Actin Cytoskeleton	Golgi Membrane Acrosomal Membrane Mitochondrion Plasma Membrane Integral Component Of Plasma Membrane Focal Adhesion Membrane Sarcolemma Melanosome Membrane Raft Extracellular Vesicular Exosome
	Molecular Function	Protein Binding Zinc Ion Binding	Protein Binding Mannose Binding
	Biological Process	Ossification Receptor-mediated Endocytosis Multicellular Organismal Development Actin Cytoskeleton Organization Cell Differentiation Positive Regulation Of Osteoblast Differentiation	Pyruvate Metabolic Process Cell Surface Receptor Signaling Pathway Embryo Implantation Blood Coagulation Extracellular Matrix Disassembly Extracellular Matrix Organization Odontogenesis Of Dentin-containing Tooth Response To Peptide Hormone Cellular Metabolic Process Small Molecule Metabolic Process Response To Mercury Ion Decidualization Leukocyte Migration Response To CAMP Protein Targeting To Plasma Membrane
Pathways			Pyruvate metabolism Pyruvate metabolism and Citric Acid (TCA) cycle Integrin cell surface interactions The citric acid (TCA) cycle and respiratory electron transport Degradation of the extracellular matrix Basigin interactions Cell surface interactions at the vascular wall
Drugs
Diseases
GWAS
Protein-Protein Interactions		34 interactors: AP5B1 BSG C20orf195 CCDC185 DGCR6 ENKD1 GEM GFAP HNRNPD IQGAP1 MDM2 PAK7 PCBP1 PHF1 PRKCA PRKCB PRKCZ PRKD2 PSMF1 RET SH2B2 SH3BP2 SMURF1 SPP1 TP53 TPM2 TRAF2 TRAF3 TSG101 UBE2I UBQLN4 WWP2 ZMYND11 ZNF165	10 interactors: CAV1 HGS MMP1 PDLIM7 PPIA PPIL2 PPP2R1B SLC16A1 SLC16A3 SLC2A4
Entrez ID		9260	682
HPRD ID		10436	00176
Ensembl ID		ENSG00000196923	ENSG00000172270
Uniprot IDs		Q9NR12	P35613 Q54A51
PDB IDs		2Q3G	3B5H 3I84 3I85 3QQN 3QR2
Enriched GO Terms of Interacting Partners?		Regulation Of Signaling Regulation Of Signal Transduction Positive Regulation Of Cellular Protein Metabolic Process Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Intracellular Signal Transduction Positive Regulation Of Protein Metabolic Process Positive Regulation Of Signal Transduction Cell Death Death Response To Organic Substance Immune System Process Regulation Of Protein Metabolic Process Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cellular Response To Organic Substance Histone H3-T6 Phosphorylation Apoptotic Process Regulation Of Cellular Protein Metabolic Process Programmed Cell Death Regulation Of Nitrogen Compound Metabolic Process Viral Process Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Protein Ubiquitination Regulation Of Metabolic Process Negative Regulation Of Signal Transduction Positive Regulation Of Cell Adhesion Cellular Response To Growth Factor Stimulus Regulation Of Apoptotic Process Protein Modification By Small Protein Conjugation Vascular Endothelial Growth Factor Receptor Signaling Pathway Response To Growth Factor Protein Catabolic Process Cell Surface Receptor Signaling Pathway Negative Regulation Of Signaling Positive Regulation Of Protein Modification Process Negative Regulation Of Apoptotic Process Positive Regulation Of NF-kappaB Transcription Factor Activity Regulation Of Cell Death Blood Coagulation Cellular Protein Modification Process Negative Regulation Of Programmed Cell Death Hemostasis Regulation Of Cellular Process Regulation Of Establishment Of Protein Localization Cellular Response To Stimulus Regulation Of Transcription, DNA-templated Negative Regulation Of Insulin Receptor Signaling Pathway Mitotic Cell Cycle Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process	Leukocyte Migration Blood Coagulation Hemostasis Regulation Of Body Fluid Levels Wound Healing Response To Wounding Cell Migration Cell Motility Lactate Transmembrane Transport Plasma Membrane Lactate Transport Lactate Transport Locomotion Movement Of Cell Or Subcellular Component Negative Regulation Of JAK-STAT Cascade Immune System Process Response To Stress Membrane Organization Protein Localization To Membrane Amylopectin Biosynthetic Process Regulation Of Membrane Repolarization During Action Potential Negative Regulation Of Peptidyl-tyrosine Autophosphorylation Uncoating Of Virus Mevalonate Transport Behavioral Response To Nutrient Protein Peptidyl-prolyl Isomerization Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Regulation Of Cellular Localization Regulation Of JAK-STAT Cascade Nitric Oxide Homeostasis Cellular Response To Oxygen Levels Transport Pyruvate Metabolic Process Monocarboxylic Acid Transport Receptor Internalization Involved In Canonical Wnt Signaling Pathway Regulation Of Cardiac Muscle Cell Action Potential Involved In Regulation Of Contraction Regulation Of Inward Rectifier Potassium Channel Activity Viral Release From Host Cell Viral Process Negative Regulation Of Tyrosine Phosphorylation Of Stat5 Protein Negative Regulation Of Pinocytosis Protein Localization To Plasma Membrane Regulation Of Secretion Caveolin-mediated Endocytosis Protein Localization To Basolateral Plasma Membrane Mammary Gland Involution Protein Localization To Plasma Membrane Raft Positive Regulation Of Metalloenzyme Activity Caveola Assembly Positive Regulation Of Transport Positive Regulation Of Apoptotic Signaling Pathway
Tagcloud ?			15q24 19q13 20q13 21q21 acquire aggressiveness akt2 angptl4 anoikis cadm2 clustered commonality ctc ctcs dissemination distinctiveness dormancy highlighting intravasation ltbp4 mcrs numbl occult originate plausible signature signatures tff3 tgfbeta
Tagcloud (Difference) ?			15q24 19q13 20q13 21q21 acquire aggressiveness akt2 angptl4 anoikis cadm2 clustered commonality ctc ctcs dissemination distinctiveness dormancy highlighting intravasation ltbp4 mcrs numbl occult originate plausible signature signatures tff3 tgfbeta
Tagcloud (Intersection) ?