GEM and APOH

Number of citations of the paper that reports this interaction (PMID 18624398)
4

Data Source:
BioGRID (two hybrid)

		GEM	APOH
Gene Name		GTP binding protein overexpressed in skeletal muscle	apolipoprotein H (beta-2-glycoprotein I)
Image
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasmic Side Of Plasma Membrane Midbody Spindle Midzone Mitotic Spindle	Extracellular Space Cell Surface Extracellular Matrix Very-low-density Lipoprotein Particle High-density Lipoprotein Particle Chylomicron Extracellular Vesicular Exosome
	Molecular Function	Magnesium Ion Binding GTPase Activity Protein Binding Calmodulin Binding GTP Binding GDP Binding	Glycoprotein Binding Protein Binding Phospholipid Binding Heparin Binding Lipid Binding Identical Protein Binding Lipoprotein Lipase Activator Activity
	Biological Process	Immune Response Mitotic Nuclear Division Signal Transduction Cell Surface Receptor Signaling Pathway Small GTPase Mediated Signal Transduction Chromosome Organization Metaphase Plate Congression	Negative Regulation Of Endothelial Cell Proliferation Triglyceride Metabolic Process Blood Coagulation, Intrinsic Pathway Negative Regulation Of Endothelial Cell Migration Negative Regulation Of Angiogenesis Positive Regulation Of Blood Coagulation Negative Regulation Of Blood Coagulation Plasminogen Activation Negative Regulation Of Myeloid Cell Apoptotic Process Triglyceride Transport Negative Regulation Of Smooth Muscle Cell Apoptotic Process Positive Regulation Of Lipoprotein Lipase Activity Regulation Of Fibrinolysis Negative Regulation Of Fibrinolysis
Pathways
Drugs
Diseases
GWAS			β2-Glycoprotein I (β2-GPI) plasma levels ( 23279374)
Protein-Protein Interactions		40 interactors: A2M AHCYL1 APOH BLZF1 BMP1 CCDC102B CCDC67 CLDN15 CLEC4G COG8 CTSL GMIP GOLGA2 IKZF3 INO80E KCTD9 KLC3 KRT31 KRT40 KRTAP10-3 KRTAP10-7 LZTS2 NDUFAF3 NDUFS8 NOTCH2NL PDLIM7 PNMA1 RNF7 RUNDC3A SDHB SSX2IP TCF4 TFIP11 TRAF1 TRIM23 TRIM27 TRIM54 VTN YBEY YWHAB	14 interactors: AKT1 ANXA2 CDC42 CLEC4G F10 F12 GEM GRB2 LPA LRP2 LRP8 PLG RBBP6 TP53
Entrez ID		2669	350
HPRD ID		11553	00728
Ensembl ID		ENSG00000164949	ENSG00000091583
Uniprot IDs		P55040	P02749
PDB IDs		2CJW 2G3Y 2HT6	1C1Z 1G4F 1G4G 1QUB 2KRI 3OP8 4JHS
Enriched GO Terms of Interacting Partners?		Cellular Component Assembly Mitochondrial Respiratory Chain Complex I Assembly Mitochondrial Respiratory Chain Complex I Biogenesis Blood Coagulation, Intrinsic Pathway Extracellular Matrix Disassembly Protein Complex Assembly Mitochondrial Respiratory Chain Complex Assembly Regulation Of Complement Activation Intracellular Transport Regulation Of Protein Binding Spliceosomal Complex Disassembly Establishment Of Localization In Cell Small GTPase Mediated Signal Transduction Extracellular Matrix Organization Extracellular Structure Organization	Regulation Of Body Fluid Levels Blood Coagulation Hemostasis Wound Healing Response To Wounding Fibrinolysis Positive Regulation Of Fibrinolysis Negative Regulation Of Blood Coagulation Negative Regulation Of Coagulation Response To Radiation Negative Regulation Of Wound Healing Labyrinthine Layer Development Organ Development Embryonic Organ Development Vesicle-mediated Transport Immune System Process In Utero Embryonic Development T Cell Costimulation Positive Regulation Of Reactive Oxygen Species Metabolic Process Regulation Of Blood Coagulation Endocytosis Positive Regulation Of Protein Metabolic Process Regulation Of Fibrinolysis Positive Regulation Of Protein Phosphorylation Response To Light Stimulus Multicellular Organism Growth Embryonic Placenta Development Immune Response Receptor-mediated Endocytosis Regulation Of Phosphorylation Blood Coagulation, Intrinsic Pathway Regulation Of Wound Healing Regulation Of Cell-cell Adhesion Chordate Embryonic Development Embryo Development Ending In Birth Or Egg Hatching Regulation Of Cellular Amino Acid Metabolic Process Positive Regulation Of Organelle Organization System Development Regulation Of Protein Metabolic Process Positive Regulation Of Phosphorylation Regulation Of Phosphorus Metabolic Process Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Regulation Of Reactive Oxygen Species Metabolic Process Positive Regulation Of Protein Modification Process Labyrinthine Layer Blood Vessel Development Regulation Of Organelle Organization Proteolysis Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Growth
Tagcloud ?		annotation centralized clinvar coherent compilation consortium curates curation das elect empowering exome expandable freestanding gbrowse guid https informs interrogation lsdb mseqdr mtdna phenotyping prioritize secure shareholders suite tracks void	avoiding cdc42 crosstalk dialog diffusible genomics germ highlighting inaccessible integrative interactomics interlaced juxtacrine membranome microsurgery mining ngfr omics pla secretome secretomes seminiferous sertoli spermatogenesis surrounded testicular tf transcriptomics tubules
Tagcloud (Difference) ?		annotation centralized clinvar coherent compilation consortium curates curation das elect empowering exome expandable freestanding gbrowse guid https informs interrogation lsdb mseqdr mtdna phenotyping prioritize secure shareholders suite tracks void	avoiding cdc42 crosstalk dialog diffusible genomics germ highlighting inaccessible integrative interactomics interlaced juxtacrine membranome microsurgery mining ngfr omics pla secretome secretomes seminiferous sertoli spermatogenesis surrounded testicular tf transcriptomics tubules
Tagcloud (Intersection) ?