PDLIM7 and AP5B1

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		PDLIM7	AP5B1
Gene Name		PDZ and LIM domain 7 (enigma)	adaptor-related protein complex 5, beta 1 subunit
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Stress Fiber Ruffle Nucleus Cytoplasm Focal Adhesion Actin Cytoskeleton	Lysosomal Membrane AP-type Membrane Coat Adaptor Complex
	Molecular Function	Protein Binding Zinc Ion Binding	Protein Binding
	Biological Process	Ossification Receptor-mediated Endocytosis Multicellular Organismal Development Actin Cytoskeleton Organization Cell Differentiation Positive Regulation Of Osteoblast Differentiation	Protein Transport Endosomal Transport
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		34 interactors: AP5B1 BSG C20orf195 CCDC185 DGCR6 ENKD1 GEM GFAP HNRNPD IQGAP1 MDM2 PAK7 PCBP1 PHF1 PRKCA PRKCB PRKCZ PRKD2 PSMF1 RET SH2B2 SH3BP2 SMURF1 SPP1 TP53 TPM2 TRAF2 TRAF3 TSG101 UBE2I UBQLN4 WWP2 ZMYND11 ZNF165	5 interactors: CALCOCO2 CAMK2B KCNRG NIF3L1 PDLIM7
Entrez ID		9260	91056
HPRD ID		10436	13223
Ensembl ID		ENSG00000196923
Uniprot IDs		Q9NR12	Q2VPB7
PDB IDs		2Q3G
Enriched GO Terms of Interacting Partners?		Regulation Of Signaling Regulation Of Signal Transduction Positive Regulation Of Cellular Protein Metabolic Process Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Intracellular Signal Transduction Positive Regulation Of Protein Metabolic Process Positive Regulation Of Signal Transduction Cell Death Death Response To Organic Substance Immune System Process Regulation Of Protein Metabolic Process Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cellular Response To Organic Substance Histone H3-T6 Phosphorylation Apoptotic Process Regulation Of Cellular Protein Metabolic Process Programmed Cell Death Regulation Of Nitrogen Compound Metabolic Process Viral Process Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Protein Ubiquitination Regulation Of Metabolic Process Negative Regulation Of Signal Transduction Positive Regulation Of Cell Adhesion Cellular Response To Growth Factor Stimulus Regulation Of Apoptotic Process Protein Modification By Small Protein Conjugation Vascular Endothelial Growth Factor Receptor Signaling Pathway Response To Growth Factor Protein Catabolic Process Cell Surface Receptor Signaling Pathway Negative Regulation Of Signaling Positive Regulation Of Protein Modification Process Negative Regulation Of Apoptotic Process Positive Regulation Of NF-kappaB Transcription Factor Activity Regulation Of Cell Death Blood Coagulation Cellular Protein Modification Process Negative Regulation Of Programmed Cell Death Hemostasis Regulation Of Cellular Process Regulation Of Establishment Of Protein Localization Cellular Response To Stimulus Regulation Of Transcription, DNA-templated Negative Regulation Of Insulin Receptor Signaling Pathway Mitotic Cell Cycle Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process	Inhibitory G-protein Coupled Receptor Phosphorylation Negative Regulation Of Delayed Rectifier Potassium Channel Activity Activation Of Meiosis Involved In Egg Activation 7,8-dihydroneopterin 3'-triphosphate Biosynthetic Process Response To Interferon-gamma Dihydrobiopterin Metabolic Process Activation Of Meiosis Regulation Of Synaptic Transmission, Cholinergic Regulation Of Delayed Rectifier Potassium Channel Activity Regulation Of Skeletal Muscle Adaptation Negative Regulation Of Potassium Ion Transmembrane Transporter Activity Regulation Of Synapse Structural Plasticity Negative Regulation Of Potassium Ion Transmembrane Transport Positive Regulation Of Dendritic Spine Morphogenesis Positive Regulation Of Synapse Maturation Desensitization Of G-protein Coupled Receptor Protein Signaling Pathway Positive Regulation Of Meiotic Nuclear Division Egg Activation Regulation Of Synapse Maturation Negative Regulation Of Cation Channel Activity Negative Regulation Of Potassium Ion Transport Positive Regulation Of Dendritic Spine Development Regulation Of Potassium Ion Transmembrane Transporter Activity Regulation Of Cellular Response To Heat Regulation Of Ion Transport Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Dendritic Spine Morphogenesis
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