PEX5 and PEX26

Number of citations of the paper that reports this interaction (PubMedID 30375424)
67

Data Source:
BioGRID (pull down)

		PEX5	PEX26
Description		peroxisomal biogenesis factor 5	peroxisomal biogenesis factor 26
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Peroxisome Peroxisomal Membrane Peroxisomal Matrix Golgi Apparatus Cytosol Membrane Protein-containing Complex	Peroxisome Peroxisomal Membrane Cytosol Membrane
	Molecular Function	Peroxisome Targeting Sequence Binding Peroxisome Matrix Targeting Signal-1 Binding Protein Binding Enzyme Binding Small GTPase Binding Peroxisome Membrane Targeting Sequence Binding Protein Carrier Chaperone	Protein Binding Protein-membrane Adaptor Activity Protein-containing Complex Binding ATPase Binding
	Biological Process	Very Long-chain Fatty Acid Metabolic Process Pexophagy Neuron Migration Protein Monoubiquitination Protein Targeting To Peroxisome Lipid Metabolic Process Fatty Acid Beta-oxidation Mitochondrion Organization Mitochondrial Membrane Organization Endoplasmic Reticulum Organization Peroxisome Organization Protein Transport Protein Import Into Peroxisome Matrix Protein Import Into Peroxisome Matrix, Docking Protein Import Into Peroxisome Matrix, Translocation Protein Import Into Peroxisome Matrix, Receptor Recycling Cerebral Cortex Cell Migration Cerebral Cortex Neuron Differentiation Negative Regulation Of Protein-containing Complex Assembly Cellular Response To Reactive Oxygen Species Positive Regulation Of Multicellular Organism Growth Protein Unfolding Protein Import Into Peroxisome Matrix, Substrate Release Protein Import Into Peroxisome Membrane Cell Development Neuromuscular Process Protein Tetramerization	Protein Transport Protein Import Into Peroxisome Matrix Protein Import Into Peroxisome Matrix, Receptor Recycling Protein To Membrane Docking Protein Unfolding Protein Import Into Peroxisome Membrane
Pathways		Pexophagy	Peroxisomal protein import Peroxisomal protein import Class I peroxisomal membrane protein import
Drugs
Diseases		Zellweger syndrome spectrum, including: Zellweger syndrome (ZS); Adrenoleukodystrophy, neonatal (NALD); Infantile Refsum disease (IRD)	Zellweger syndrome spectrum, including: Zellweger syndrome (ZS); Adrenoleukodystrophy, neonatal (NALD); Infantile Refsum disease (IRD)
GWAS		IgG glycosylation ( 23382691) Night sleep phenotypes ( 27126917) Refractive error ( 32231278)
Interacting Genes		77 interacting genes: ACD ACOT2 ACOT4 ACOT8 ACOX2 ACOX3 AGXT AMACR ANKRD50 ATM BAAT BRCA1 CAPRIN2 CCDC14 CROT DAO DDO DECR2 DHRS4 ECI2 EP400P1 EPHX2 GDPD5 GLMN GNPAT GSTK1 HACL1 HAO1 HAO2 HMGCL HNRNPH1 HOXA7 HSPA1A IDE IDH1 LDHB LONP2 MKRN3 MLYCD MPV17 NOS2 NUDT19 NUDT3 NUDT7 NUFIP2 PAOX PDZK1 PEX1 PEX10 PEX12 PEX13 PEX14 PEX26 PEX6 PEX7 PIPOX POT1 PRDX5 PRR13 PSAP RPL14 S100A6 SCARB1 SCP2 SCRN2 SIRT3 SLC27A2 SNUPN SSTR5 TIMMDC1 TINF2 TM6SF1 TOMM7 USP2 USP9X ZFAND3 ZNF772	6 interacting genes: PEX1 PEX14 PEX19 PEX5 PEX6 SUFU
Entrez ID		5830	55670
HPRD ID		02684	10559
Ensembl ID		ENSG00000139197	ENSG00000215193
Uniprot IDs		A0A0S2Z480 A0A0S2Z4F3 A0A0S2Z4H1 B4DR50 B4E0T2 P50542	A0A024R100 A0A0S2Z5M7 Q7Z412
PDB IDs		1FCH 2C0L 2C0M 2J9Q 2W84 3R9A 4BXU 4KXK 4KYO 7Z0K 9GAG
Enriched GO Terms of Interacting Partners?		Peroxisome Peroxisomal Matrix Carboxylic Acid Catabolic Process Establishment Of Protein Localization To Peroxisome Protein Import Into Peroxisome Matrix Fatty Acid Oxidation Carboxylic Acid Metabolic Process Fatty Acid Catabolic Process Organic Acid Metabolic Process Lipid Oxidation Peroxisome Organization Fatty Acid Metabolic Process Monocarboxylic Acid Metabolic Process Peroxisomal Membrane Transport Peroxisomal Membrane Lipid Modification Protein Import Into Peroxisome Matrix, Receptor Recycling Intracellular Protein Transmembrane Transport Fatty Acid Beta-oxidation Using Acyl-CoA Oxidase Small Molecule Metabolic Process Lipid Metabolic Process Protein Unfolding Lipid Catabolic Process Protein Transmembrane Transport Catabolic Process Fatty Acid Beta-oxidation Receptor Recycling Protein Targeting To Peroxisome Cytosol Establishment Of Protein Localization To Organelle Receptor Metabolic Process Sulfur Compound Metabolic Process Acyl-CoA Metabolic Process Bile Acid Biosynthetic Process Carboxylic Acid Biosynthetic Process Protein Import Into Peroxisome Matrix, Substrate Release Bile Acid Metabolic Process Fatty Acid Alpha-oxidation Oxidoreductase Activity Protein Localization To Organelle Purine-containing Compound Metabolic Process Small Molecule Biosynthetic Process Peroxisomal Importomer Complex Malonyl-CoA Catabolic Process Protein Transmembrane Transporter Activity Nucleoside Phosphate Metabolic Process Nucleobase-containing Small Molecule Metabolic Process Protein Import Into Peroxisome Matrix, Translocation Telomere Assembly Organophosphate Metabolic Process	Establishment Of Protein Localization To Peroxisome Peroxisomal Membrane Transport Peroxisome Organization Protein Targeting To Peroxisome Protein Import Into Peroxisome Matrix, Receptor Recycling Protein Unfolding Protein Import Into Peroxisome Matrix Peroxisomal Membrane Receptor Recycling Protein Import Into Peroxisome Matrix, Translocation Intracellular Protein Transmembrane Transport Peroxisome Receptor Metabolic Process Protein Transmembrane Transport Establishment Of Protein Localization To Organelle Peroxisome Membrane Targeting Sequence Binding Intracellular Protein Transport Intracellular Transport Protein Targeting Protein Import Into Peroxisome Matrix, Docking Protein Localization To Organelle Protein Import Into Peroxisome Matrix, Substrate Release Protein Import Into Peroxisome Membrane Cellular Localization Establishment Of Localization In Cell Ubiquitin-modified Protein Reader Activity Protein Carrier Chaperone Protein Transporter Activity Protein Transport Transmembrane Transport Response To Reactive Oxygen Species Establishment Of Protein Localization Organelle Organization Protein-containing Complex Skin Development Intracellular Protein Localization Protein Monoubiquitination Response To Oxidative Stress Response To Polyamine Macromolecule Peroxisome Transport Along Microtubule Negative Regulation Of Lipid Binding Peroxisome Membrane Class-1 Targeting Sequence Binding Regulation Of Cellular Response To Drug Positive Regulation Of Cellular Response To Drug Protein Tetramerization Multicellular Organismal Locomotion Microtubule-based Peroxisome Localization Peroxisome Matrix Targeting Signal-1 Binding Smoothened Signaling Pathway Involved In Spinal Cord Motor Neuron Cell Fate Specification Positive Regulation Of Response To Drug
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