PEX5 and DECR2

Number of citations of the paper that reports this interaction (PMID 22002062)
8

Data Source:
BioGRID (unspecified method, affinity chromatography technology)

		PEX5	DECR2
Gene Name		peroxisomal biogenesis factor 5	2,4-dienoyl CoA reductase 2, peroxisomal
Image
Gene Ontology Annotations	Cellular Component	Intracellular Cytoplasm Peroxisome Peroxisomal Membrane Peroxisomal Matrix Golgi Apparatus Cytosol Membrane Protein Complex	Peroxisomal Membrane
	Molecular Function	Peroxisome Targeting Sequence Binding Peroxisome Matrix Targeting Signal-1 Binding Protein Binding Protein C-terminus Binding Enzyme Binding Small GTPase Binding Protein N-terminus Binding	Receptor Binding 2,4-dienoyl-CoA Reductase (NADPH) Activity Trans-2-enoyl-CoA Reductase (NADPH) Activity
	Biological Process	Protein Targeting To Peroxisome Protein Import Into Peroxisome Matrix Protein Import Into Peroxisome Matrix, Docking Protein Import Into Peroxisome Matrix, Translocation Protein Import Into Peroxisome Membrane Protein Tetramerization Negative Regulation Of Protein Homotetramerization	Unsaturated Fatty Acid Biosynthetic Process Oxidation-reduction Process
Pathways
Drugs
Diseases
GWAS		IgG glycosylation ( 23382691)
Protein-Protein Interactions		68 interactors: ACD ACOT2 ACOT4 ACOT8 ACOX2 ACOX3 AGXT AMACR ATM BAAT BRCA1 CAPRIN2 CCDC14 CROT DAO DDO DECR2 DHRS4 ECH1 ECI2 EP400NL EPHX2 FIS1 GDPD5 GNPAT GSTK1 HACL1 HAO1 HAO2 HMGCL HOXA7 HSPA1A IDE IDH1 LDHB LONP2 MKRN3 MLYCD MPV17 NOS2 NUDT19 NUDT3 NUDT7 PAOX PDZK1 PECR PEX10 PEX12 PEX13 PEX14 PEX7 PIPOX POT1 PRDX5 PRR13 RPL14 S100A6 SCARB1 SCP2 SIRT3 SLC27A2 SNUPN SSTR5 TINF2 TM6SF1 TOMM7 USP9X ZNF772	5 interactors: APP EP300 NEDD4L PEX5 UBC
Entrez ID		5830	26063
HPRD ID		02684	16789
Ensembl ID		ENSG00000139197	ENSG00000242612
Uniprot IDs		B4DR50 B4E0T2 P50542	Q9NUI1
PDB IDs		1FCH 2C0L 2C0M 2J9Q 2W84 3R9A	4FC6 4FC7
Enriched GO Terms of Interacting Partners?		Carboxylic Acid Catabolic Process Monocarboxylic Acid Metabolic Process Fatty Acid Metabolic Process Carboxylic Acid Metabolic Process Organic Acid Metabolic Process Small Molecule Metabolic Process Fatty Acid Oxidation Catabolic Process Lipid Oxidation Fatty Acid Catabolic Process Lipid Metabolic Process Cellular Lipid Metabolic Process Lipid Modification Cellular Lipid Catabolic Process Lipid Catabolic Process Peroxisome Organization Oxidation-reduction Process Fatty Acid Beta-oxidation Fatty Acid Beta-oxidation Using Acyl-CoA Oxidase Protein Import Into Peroxisome Matrix Cellular Metabolic Process Acyl-CoA Metabolic Process Protein Targeting To Peroxisome Establishment Of Protein Localization To Peroxisome Bile Acid Biosynthetic Process Intracellular Protein Transmembrane Transport Cofactor Metabolic Process Protein Transmembrane Transport Lipid Biosynthetic Process Bile Acid Metabolic Process Fatty Acid Alpha-oxidation Sulfur Compound Metabolic Process Glyoxylate Metabolic Process Protein Import Protein Localization To Organelle Establishment Of Protein Localization To Organelle Steroid Biosynthetic Process Protein Targeting Telomere Assembly Metabolic Process Negative Regulation Of Telomere Maintenance Via Telomerase Steroid Metabolic Process Cellular Amino Acid Catabolic Process Long-chain Fatty Acid Metabolic Process Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of Chromosome Organization Cellular Process Dicarboxylic Acid Catabolic Process Coenzyme A Catabolic Process	Notch Signaling Pathway Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Response To Abiotic Stimulus Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Positive Regulation Of Type I Interferon Production Regulation Of ERBB Signaling Pathway Viral Process Regulation Of Multicellular Organism Growth Cellular Response To Hypoxia Regulation Of Transcription From RNA Polymerase II Promoter Cellular Response To Decreased Oxygen Levels Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Type I Interferon Production Negative Regulation Of Cellular Response To Growth Factor Stimulus Histone H2B Acetylation Cellular Response To Oxygen Levels Signal Transduction By P53 Class Mediator G2/M Transition Of Mitotic Cell Cycle Neuromuscular Process Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Protein Metabolic Process Transforming Growth Factor Beta Receptor Signaling Pathway Innate Immune Response Regulation Of Protein Binding Negative Regulation Of Protein Homotetramerization Synaptic Growth At Neuromuscular Junction Positive Regulation Of Caveolin-mediated Endocytosis Transcription Initiation From RNA Polymerase II Promoter Protein Polyubiquitination Circadian Rhythm Regulation Of Cell Cycle Regulation Of Cellular Response To Growth Factor Stimulus Cellular Response To Transforming Growth Factor Beta Stimulus N-terminal Peptidyl-lysine Acetylation Protein Import Into Peroxisome Matrix, Translocation Collateral Sprouting In Absence Of Injury Viral Life Cycle Response To Transforming Growth Factor Beta Apoptotic Process Intracellular Receptor Signaling Pathway Programmed Cell Death Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Unfolded Protein Response
Tagcloud ?		behave behaves cargo cooperatively couple cytosol deubiquitination differently disuse energetics folded identically import importers importomer lumen organelles peroxisomal peroxisome peroxisomes pexophagy shuttle stochastic traffic translationally translocated translocation ubiquitin uncoupled
Tagcloud (Difference) ?		behave behaves cargo cooperatively couple cytosol deubiquitination differently disuse energetics folded identically import importers importomer lumen organelles peroxisomal peroxisome peroxisomes pexophagy shuttle stochastic traffic translationally translocated translocation ubiquitin uncoupled
Tagcloud (Intersection) ?