PEX5 and ECI2

Number of citations of the paper that reports this interaction (PMID 22002062)
8

Data Source:
BioGRID (unspecified method, affinity chromatography technology)

		PEX5	ECI2
Gene Name		peroxisomal biogenesis factor 5	enoyl-CoA delta isomerase 2
Image
Gene Ontology Annotations	Cellular Component	Intracellular Cytoplasm Peroxisome Peroxisomal Membrane Peroxisomal Matrix Golgi Apparatus Cytosol Membrane Protein Complex	Nucleoplasm Mitochondrion Peroxisomal Matrix Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Peroxisome Targeting Sequence Binding Peroxisome Matrix Targeting Signal-1 Binding Protein Binding Protein C-terminus Binding Enzyme Binding Small GTPase Binding Protein N-terminus Binding	Fatty-acyl-CoA Binding Dodecenoyl-CoA Delta-isomerase Activity Receptor Binding
	Biological Process	Protein Targeting To Peroxisome Protein Import Into Peroxisome Matrix Protein Import Into Peroxisome Matrix, Docking Protein Import Into Peroxisome Matrix, Translocation Protein Import Into Peroxisome Membrane Protein Tetramerization Negative Regulation Of Protein Homotetramerization	Metabolic Process Fatty Acid Catabolic Process
Pathways
Drugs
Diseases
GWAS		IgG glycosylation ( 23382691)	Obesity-related traits ( 23251661)
Protein-Protein Interactions		68 interactors: ACD ACOT2 ACOT4 ACOT8 ACOX2 ACOX3 AGXT AMACR ATM BAAT BRCA1 CAPRIN2 CCDC14 CROT DAO DDO DECR2 DHRS4 ECH1 ECI2 EP400NL EPHX2 FIS1 GDPD5 GNPAT GSTK1 HACL1 HAO1 HAO2 HMGCL HOXA7 HSPA1A IDE IDH1 LDHB LONP2 MKRN3 MLYCD MPV17 NOS2 NUDT19 NUDT3 NUDT7 PAOX PDZK1 PECR PEX10 PEX12 PEX13 PEX14 PEX7 PIPOX POT1 PRDX5 PRR13 RPL14 S100A6 SCARB1 SCP2 SIRT3 SLC27A2 SNUPN SSTR5 TINF2 TM6SF1 TOMM7 USP9X ZNF772	3 interactors: APP KDM1A PEX5
Entrez ID		5830	10455
HPRD ID		02684	16269
Ensembl ID		ENSG00000139197	ENSG00000198721
Uniprot IDs		B4DR50 B4E0T2 P50542	O75521
PDB IDs		1FCH 2C0L 2C0M 2J9Q 2W84 3R9A	2CQU 2F6Q
Enriched GO Terms of Interacting Partners?		Carboxylic Acid Catabolic Process Monocarboxylic Acid Metabolic Process Fatty Acid Metabolic Process Carboxylic Acid Metabolic Process Organic Acid Metabolic Process Small Molecule Metabolic Process Fatty Acid Oxidation Catabolic Process Lipid Oxidation Fatty Acid Catabolic Process Lipid Metabolic Process Cellular Lipid Metabolic Process Lipid Modification Cellular Lipid Catabolic Process Lipid Catabolic Process Peroxisome Organization Oxidation-reduction Process Fatty Acid Beta-oxidation Fatty Acid Beta-oxidation Using Acyl-CoA Oxidase Protein Import Into Peroxisome Matrix Cellular Metabolic Process Acyl-CoA Metabolic Process Protein Targeting To Peroxisome Establishment Of Protein Localization To Peroxisome Bile Acid Biosynthetic Process Intracellular Protein Transmembrane Transport Cofactor Metabolic Process Protein Transmembrane Transport Lipid Biosynthetic Process Bile Acid Metabolic Process Fatty Acid Alpha-oxidation Sulfur Compound Metabolic Process Glyoxylate Metabolic Process Protein Import Protein Localization To Organelle Establishment Of Protein Localization To Organelle Steroid Biosynthetic Process Protein Targeting Telomere Assembly Metabolic Process Negative Regulation Of Telomere Maintenance Via Telomerase Steroid Metabolic Process Cellular Amino Acid Catabolic Process Long-chain Fatty Acid Metabolic Process Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of Chromosome Organization Cellular Process Dicarboxylic Acid Catabolic Process Coenzyme A Catabolic Process	Forebrain Development Brain Development Head Development Regulation Of Multicellular Organism Growth Central Nervous System Development Neuromuscular Process Regulation Of Protein Binding Regulation Of Primitive Erythrocyte Differentiation Negative Regulation Of Protein Homotetramerization Synaptic Growth At Neuromuscular Junction Protein Import Into Peroxisome Matrix, Translocation Collateral Sprouting In Absence Of Injury Regulation Of Binding Regulation Of Developmental Growth Protein Import Into Peroxisome Matrix, Docking Cell Development Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Negative Regulation Of Protein Homooligomerization Axon Choice Point Recognition Protein Import Into Peroxisome Membrane Negative Regulation Of Histone H3-K4 Methylation Histone H3-K9 Demethylation Protein To Membrane Docking Histone H3-K4 Demethylation Nervous System Development Blood Coagulation Hemostasis Peroxisomal Membrane Transport Neuron Remodeling Negative Regulation Of Protein Oligomerization Positive Regulation Of Megakaryocyte Differentiation Positive Regulation Of Hormone Biosynthetic Process Negative Regulation Of Histone H3-K9 Methylation Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Protein Import Into Peroxisome Matrix Regulation Of Body Fluid Levels Negative Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Wound Healing Regulation Of Growth Granulocyte Differentiation Organ Development Cellular Copper Ion Homeostasis Regulation Of Megakaryocyte Differentiation Negative Regulation Of Histone Methylation Response To Wounding Positive Regulation Of Erythrocyte Differentiation Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator
Tagcloud ?		behave behaves cargo cooperatively couple cytosol deubiquitination differently disuse energetics folded identically import importers importomer lumen organelles peroxisomal peroxisome peroxisomes pexophagy shuttle stochastic traffic translationally translocated translocation ubiquitin uncoupled
Tagcloud (Difference) ?		behave behaves cargo cooperatively couple cytosol deubiquitination differently disuse energetics folded identically import importers importomer lumen organelles peroxisomal peroxisome peroxisomes pexophagy shuttle stochastic traffic translationally translocated translocation ubiquitin uncoupled
Tagcloud (Intersection) ?