POLA2 and PARP1

  • Number of citations of the paper that reports this interaction (PMID 9518481)
  • 25
  • Data Source:
  • BioGRID (far western blotting)

POLA2

PARP1

Gene Name polymerase (DNA directed), alpha 2, accessory subunit poly (ADP-ribose) polymerase 1
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 31 interactors: AKTIP APP ASCC2 ATP5C1 CPE CRELD1 DCP2 DDX24 DHX34 EIF6 EZH2 FAM219A FGFR3 FRZB HDAC6 HELB HGH1 IGFBP3 KCNE3 KLF6 LRPAP1 NHP2L1 NR4A1 PARP1 POLA1 PRPF38A RBM23 SETDB1 STK40 ULK2 XPNPEP1 84 interactors: APLF APTX ATM BCL2 BUB3 CASP1 CASP3 CASP7 CASP8 CD86 CDKN1A CENPA CENPB CREBBP CTSB CTSG E2F1 ERCC6 ERG FOXO1 GTF2F1 GZMB GZMM H2AFY HDAC1 HDAC3 HIST1H1A HIST1H1C HIST1H2BA HIST1H4A HIST1H4C HIST2H2AA3 HMGA1 HOXB7 HSPA2 KAT2B LIG3 LZTR1 MED14 MED6 MYBL2 NCL NCOA6 NEDD8 NFATC1 NFKB1 NPM1 NRF1 PARP2 PARP3 PCNA PIAS4 POLA1 POLA2 POLB POU2F1 PRKDC RARA RBM14 RELA RNF146 RPS3A RXRA SENP1 SENP3 SIRT1 SP1 SREK1 SUMO1 SUMO2 SUPT16H SWAP70 TCF4 TP53 TRIM29 UBE2I UHRF1 WRN XRCC1 XRCC5 XRCC6 ZBTB16 ZBTB9 ZNF423
Entrez ID 23649 142
HPRD ID 10160 01435
Ensembl ID ENSG00000143799
Uniprot IDs Q14181 P09874
PDB IDs 2KEB 4E2I 1UK0 1UK1 1WOK 2COK 2CR9 2CS2 2DMJ 2JVN 2L30 2L31 2RCW 2RD6 2RIQ 3GJW 3GN7 3L3L 3L3M 3OD8 3ODA 3ODC 3ODE 4AV1 4DQY 4GV7 4HHY 4HHZ 4L6S
Enriched GO Terms of Interacting Partners?
Tagcloud ?
beadchip  ca125  carboplatin  cdkn1b  chek2  ck7  cyfra21  cytokinesis  deserve  exceptional  fancd2  illumina  krt7  lig3  mesothelioma  nt5c  obscure  pemetrexed  phosphorylase  platinum  pold1  prpf19  recq5  sensitize  smrp  sparcl1  transendothelial  ts  tymp 
ageing  ascribes  atm  attrition  brca1  complexity  ctip  ends  fusions  homologous  instability  insufficient  joining  ku70  lig3  lig4  mechanistically  nhej  overhang  rampant  relies  repeats  telomere  telomeres  telomeric  trf2  unanticipated  uncapped  underlining 
Tagcloud (Difference) ?
beadchip  ca125  carboplatin  cdkn1b  chek2  ck7  cyfra21  cytokinesis  deserve  exceptional  fancd2  illumina  krt7  mesothelioma  nt5c  obscure  pemetrexed  phosphorylase  platinum  pold1  prpf19  recq5  sensitize  smrp  sparcl1  transendothelial  ts  tymp 
ageing  ascribes  atm  attrition  brca1  complexity  ctip  ends  fusions  homologous  instability  insufficient  joining  ku70  lig4  mechanistically  nhej  overhang  rampant  relies  repeats  telomere  telomeres  telomeric  trf2  unanticipated  uncapped  underlining 
Tagcloud (Intersection) ?
lig3